{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T08:12:19Z","timestamp":1776759139401,"version":"3.51.2"},"reference-count":20,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2012,11,20]],"date-time":"2012-11-20T00:00:00Z","timestamp":1353369600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Ophthalmologica"],"published-print":{"date-parts":[[2014,3]]},"abstract":"<jats:title>Abstract.<\/jats:title><jats:p><jats:bold>Purpose:\u2002<\/jats:bold> To determine the incidence rate as well as causative diagnoses and surgical indications of enucleation in Iceland during the years 1992\u20132004.<\/jats:p><jats:p><jats:bold>Methods:\u2002<\/jats:bold> A retrospective population\u2010based incidence study involving the entire population of Iceland. Medical records of all patients who underwent enucleation in Iceland from January 1992 through December 2004 were reviewed. The annually updated Icelandic census was used as a denominator data.<\/jats:p><jats:p><jats:bold>Results:\u2002<\/jats:bold> Fifty\u2010six eyes were enucleated during 1992\u20132004. No eviscerations were done, and the three exenterations performed were not included in the study. The mean annual age\u2010adjusted incidence rate of enucleation in Iceland was 1.48 enucleations per 100\u2003000 population in comparison with 2.66 enucleations per 100\u2003000 for the time period 1964\u20131991. With advancing age, a significant increasing linear trend existed (p\u2003&lt;\u20030.001). The median age at enucleation was 51\u2003years (SD 22; mean 55\u2003years; 16\u201391\u2003years). The three most common surgical indications for enucleation were blind painful eye, suspected ocular malignancy and acute trauma. The most common causative diagnosis for enucleation was traumatic lesion (39%). The annual incidence was 2.00 enucleations per 100\u2003000 for men and 0.95 for women. There were significantly more men in the traumatic lesion group (p\u2003&lt;\u20030.001), but no gender predominance was found in the other groups of causative diagnoses (p\u2003=\u20030.8).<\/jats:p><jats:p><jats:bold>Conclusion:\u2002<\/jats:bold> The overall mean annual incidence of enucleation in Iceland is continually decreasing, although the incidence of severe ocular trauma and ocular malignancy is fairly stable.<\/jats:p>","DOI":"10.1111\/aos.12004","type":"journal-article","created":{"date-parts":[[2012,11,20]],"date-time":"2012-11-20T12:21:11Z","timestamp":1353414071000},"page":"121-125","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Enucleation in Iceland 1992\u20132004: study in a defined population"],"prefix":"10.1111","volume":"92","author":[{"given":"Asbjorg","family":"Geirsdottir","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bjarni A.","family":"Agnarsson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gudleif","family":"Helgadottir","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haraldur","family":"Sigurdsson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,11,20]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1177\/112067210701700424","article-title":"Causes of enucleation in Northern India (1995\u20132005)","volume":"17","author":"Bal A","year":"2007","journal-title":"Eur J Ophthalmol"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10792-007-9105-2"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/00002341-200009000-00004"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9394(14)71525-9"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.78.4.260"},{"key":"e_1_2_6_7_1","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1177\/112067219700700304","article-title":"Causes of enucleation: a clinicopathological study","volume":"7","author":"G\u00fcnalp I","year":"1997","journal-title":"Eur J Ophthalmol"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0420.1999.770317.x"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1023\/A:1023684502638"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0420.2004.00330.x"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1309\/MLRMQWAFV6A115UA"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0420.1997.tb00766.x"},{"key":"e_1_2_6_13_1","doi-asserted-by":"crossref","unstructured":"OECD(2010).OECD Factbook 2010: Economic environmental and social statistics.OECD iLibrary. 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