{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T10:38:54Z","timestamp":1785839934741,"version":"3.56.0"},"reference-count":24,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2013,7,23]],"date-time":"2013-07-23T00:00:00Z","timestamp":1374537600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Ophthalmologica"],"published-print":{"date-parts":[[2014,6]]},"abstract":"<jats:title>Abstract.<\/jats:title><jats:p><jats:bold>Purpose:\u2002<\/jats:bold> To determine the effect of pseudoexfoliation (PEX) on the development of Alzheimer\u2019s disease (AD) in a population in which PEX is a common finding. The relationship between open\u2010angle glaucoma (OAG) and AD was also studied.<\/jats:p><jats:p><jats:bold>Methods:\u2002<\/jats:bold> Predictors of incident AD, including mixed and unspecified dementia, were analysed in a cohort of 679 residents 65\u201374\u2003years of age, examined in a population survey in the municipality of Tierp, Sweden, 1984\u20131986. To expand the cohort, participants in other studies in Tierp were enrolled. In this way, the cohort embraced 1123 people, representing more than 15\u2003700 person\u2010years at risk. Medical records were reviewed to identify subjects diagnosed with dementia. Those with a follow\u2010up time shorter than 2\u2003years were excluded from the study.<\/jats:p><jats:p><jats:bold>Results:\u2002<\/jats:bold> By the conclusion of the study, in December 2011, 174 new cases of AD, including mixed and unspecified dementia, had been detected, 41 of whom were affected by PEX at baseline. Higher age and female gender were the only predictors identified. No association between PEX and AD was found (hazard ratio 0.98; 95% confidence interval 0.69\u20131.40). Newly diagnosed OAG at baseline did not increase the risk (hazard ratio 1.09; 95% confidence interval 0.69\u20131.74).<\/jats:p><jats:p><jats:bold>Conclusion:\u2002<\/jats:bold> Pseudoexfoliation is not a predictor of AD. No association was found between OAG and AD.<\/jats:p>","DOI":"10.1111\/aos.12184","type":"journal-article","created":{"date-parts":[[2013,7,24]],"date-time":"2013-07-24T13:30:52Z","timestamp":1374672652000},"page":"355-358","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":34,"title":["Pseudoexfoliation and Alzheimer\u2019s disease: a population\u2010based 30\u2010year follow\u2010up study"],"prefix":"10.1111","volume":"92","author":[{"given":"Curt","family":"Ekstr\u00f6m","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lena","family":"Kilander","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,7,23]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1159\/000047976"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1755-3768.1993.tb04989.x"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0420.1996.tb00052.x"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1755-3768.2010.01943.x"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.86.2.238"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-323-03707-5.50024-3"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/9780470258019"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0420.2001.790327.x"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/IJG.0b013e31802b3527"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/IJG.0b013e3181ca76c4"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0420.2001.790314.x"},{"issue":"11","key":"e_1_2_6_13_1","first-page":"S4","article-title":"Prevalence of dementia and major subtypes in Europe: a collaborative study of population\u2010based cohorts. 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