{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T08:44:17Z","timestamp":1790671457007,"version":"4.1.0"},"reference-count":17,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2013,7,10]],"date-time":"2013-07-10T00:00:00Z","timestamp":1373414400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Ophthalmologica"],"published-print":{"date-parts":[[2014,8]]},"abstract":"<jats:title>Abstract.<\/jats:title><jats:p><jats:bold>Purpose:\u2002<\/jats:bold> To investigate factors associated with bilateral glaucoma blindness, particularly factors available at the time of diagnosis.<\/jats:p><jats:p><jats:bold>Methods:\u2002<\/jats:bold> Retrospective chart review of all patients with primary open\u2010angle glaucoma (POAG) or pseudoexfoliative glaucoma (PEXG) followed at the Department of Ophthalmology or Low Vision Center of Sk\u00e5ne University Hospital, Malm\u00f6, Sweden, who died between January 2006 and June 2010. Disease stage at diagnosis was defined by a simplified version of Mills\u2019 glaucoma staging system using perimetric mean deviation (MD) to define six stages of severity. Blindness was defined according to WHO criteria. We used logistic regression analysis to examine the association between risk factors and glaucoma blindness.<\/jats:p><jats:p><jats:bold>Results:\u2002<\/jats:bold> Four hundred and 23 patients were included; 60% POAG and 40% PEXG. Sixty\u2010four patients (15%) became blind from glaucoma. Blind patients had significantly longer mean duration with diagnosed disease than patients who did not go blind (14.8\u2003years\u2003\u00b1\u20035.8 versus 10.6\u2003years\u2003\u00b1\u20036.5, p\u2003&lt;\u20030.001). The risk of blindness increased with higher intraocular pressure (IOP) (OR 1.08, 95% CI 1.03\u20131.13) and with each stage of more advanced field loss at time of diagnosis (OR 1.80 95% CI 1.34\u20132.41). Older age at death was also associated with an increased risk of blindness (OR 1.09 95% CI 1.03\u20131.14), while age at diagnosis was unimportant. PEXG was not an independent risk factor for blindness.<\/jats:p><jats:p><jats:bold>Conclusions:\u2002<\/jats:bold> Higher IOP and worse visual field status at baseline were important risk factors, as was older age at death.<\/jats:p>","DOI":"10.1111\/aos.12203","type":"journal-article","created":{"date-parts":[[2013,7,10]],"date-time":"2013-07-10T10:29:01Z","timestamp":1373452141000},"page":"421-425","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":122,"title":["Factors associated with lifetime risk of open\u2010angle glaucoma blindness"],"prefix":"10.1111","volume":"92","author":[{"given":"Dorothea","family":"Peters","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Boel","family":"Bengtsson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anders","family":"Heijl","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,7,10]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.eye.6702284"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.ijg.0000151683.04410.f3"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(02)01974-7"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/IJG.0b013e318033500f"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1442-9071.2011.02559.x"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(82)34675-8"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.1980.01020040412002"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2415-11-31"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.2147\/OPTH.S3139"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9394(01)00912-6"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.121.1.48"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2005.07.044"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9394(02)01403-4"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(99)90516-X"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/ICU.0b013e328324e6c4"},{"key":"e_1_2_6_17_1","unstructured":"Social Security Ruling SSR 07\u201001 p; Titles II and XVI: Evaluating Visual Field Loss Using Automated Static Threshold Perimetry. 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