{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T02:12:57Z","timestamp":1773281577335,"version":"3.50.1"},"reference-count":19,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2014,1,30]],"date-time":"2014-01-30T00:00:00Z","timestamp":1391040000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["30872820"],"award-info":[{"award-number":["30872820"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Ophthalmologica"],"published-print":{"date-parts":[[2014,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>To assess tuberculous uveitis in <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>hinese patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The hospital\u2010based observational case series study included patients who attended a third\u2010referral hospital and presented with chronic and recurrent uveitis without primarily detected aetiology. The patients underwent the tuberculin skin test (<jats:styled-content style=\"fixed-case\">TST<\/jats:styled-content>) and\/or interferon gamma release test (<jats:styled-content style=\"fixed-case\">IGRA<\/jats:styled-content>). Patients with positive test results received standard antituberculous therapy. Patients who responded to the therapy and did not show recurrence of uveitis in the follow\u2010up period were diagnosed as tuberculous uveitis and formed the study group. The remaining patients were diagnosed as non\u2010tuberculous uveitis and formed the control group. The clinical characteristics were compared between both groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The study group with tuberculous uveitis included 46 patients and the non\u2010tuberculous group 38 patients. Multifocal choroiditis [<jats:italic>n<\/jats:italic>\u00a0=\u00a09 (20%) versus <jats:italic>n<\/jats:italic>\u00a0=\u00a01(3%); p<jats:italic>\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.04] and retinal vasculitis [<jats:italic>n<\/jats:italic>\u00a0=\u00a025(54%) versus 8\u00a0=\u00a0(21.1%); p<jats:italic>\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.002] were significantly more common in the study group. Of 25 patients with retinal vasculitis in the study group, 11 patients (44%) additionally showed choroiditis lesions, compared with only one (13%) of eight patients in the control group (p<jats:italic>\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.01). In multivariate regression analysis, multifocal choroiditis [odds ratio (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>): 32.1], choroidal granuloma (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>: 21.4) and retinal vasculitis (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>: 11.2) were independent predictors of tubercular uveitis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>About 50% of a group of 84 patients with primarily unexplained chronic posterior uveitis had tuberculosis and showed multifocal choroiditis, choroidal granuloma and retinal vasculitis. These features had a high predictive value for the diagnosis of tuberculous uveitis. Tuberculosis is an important part in the differential diagnosis of unexplained uveitis.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aos.12351","type":"journal-article","created":{"date-parts":[[2014,1,30]],"date-time":"2014-01-30T12:51:39Z","timestamp":1391086299000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Tuberculous uveitis in <scp>C<\/scp>hina"],"prefix":"10.1111","volume":"92","author":[{"given":"Yu","family":"Mao","sequence":"first","affiliation":[{"name":"Beijing Institute of Ophthalmology Beijing Ophthalmology and Visual Science Key Lab Beijing Tongren Eye Center Beijing Tongren Hospital Capital Medical University Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiao Yan","family":"Peng","sequence":"additional","affiliation":[{"name":"Beijing Institute of Ophthalmology Beijing Ophthalmology and Visual Science Key Lab Beijing Tongren Eye Center Beijing Tongren Hospital Capital Medical University Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qi Sheng","family":"You","sequence":"additional","affiliation":[{"name":"Beijing Institute of Ophthalmology Beijing Ophthalmology and Visual Science Key Lab Beijing Tongren Eye Center Beijing Tongren Hospital Capital Medical University Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hong","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology Beijing Ophthalmology and Visual Science Key Lab Beijing Tongren Eye Center Beijing Tongren Hospital Capital Medical University Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meng","family":"Zhao","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology Beijing Ophthalmology and Visual Science Key Lab Beijing Tongren Eye Center Beijing Tongren Hospital Capital Medical University Beijing 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