{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T05:23:09Z","timestamp":1791177789591,"version":"4.1.0"},"reference-count":26,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2014,1,25]],"date-time":"2014-01-25T00:00:00Z","timestamp":1390608000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"ARFO (association for teaching and research in ophthalmology), Grenoble, France"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Ophthalmologica"],"published-print":{"date-parts":[[2014,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>In non\u2010arteritic anterior ischaemic optic neuropathy (<jats:styled-content style=\"fixed-case\">NAAION<\/jats:styled-content>) patients, circulatory insufficiency within the optic nerve has previously been hypothesized to be related to nocturnal systemic hypotension. The main objective of this prospective cohort study was to investigate the nyctohemeral variations in ocular perfusion pressure (<jats:styled-content style=\"fixed-case\">OPP<\/jats:styled-content>) in <jats:styled-content style=\"fixed-case\">NAAION<\/jats:styled-content> patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In 20 patients with <jats:styled-content style=\"fixed-case\">NAAION<\/jats:styled-content>, the intraocular pressure (<jats:styled-content style=\"fixed-case\">IOP<\/jats:styled-content>) was measured using the <jats:styled-content style=\"fixed-case\">T<\/jats:styled-content>ono\u2010Pen <jats:styled-content style=\"fixed-case\">XL<\/jats:styled-content><jats:sup>\u2122<\/jats:sup> electronic tonometer every hour for 24\u00a0hr. Blood pressure (<jats:styled-content style=\"fixed-case\">BP<\/jats:styled-content>) was evaluated over 24\u00a0hr. Mean <jats:styled-content style=\"fixed-case\">OPP<\/jats:styled-content> was calculated with the following formula: <jats:styled-content style=\"fixed-case\">OPP<\/jats:styled-content> <jats:sub>sitting position<\/jats:sub>\u00a0=\u00a0(0.74\u00a0\u00d7\u00a0mean <jats:styled-content style=\"fixed-case\">BP<\/jats:styled-content>) \u2212 <jats:styled-content style=\"fixed-case\">IOP<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">OPP<\/jats:styled-content> <jats:sub>lying position<\/jats:sub>\u00a0=\u00a0(0.84\u00a0\u00d7\u00a0mean <jats:styled-content style=\"fixed-case\">BP<\/jats:styled-content>) \u2212 <jats:styled-content style=\"fixed-case\">IOP<\/jats:styled-content>. A nonlinear least squares dual\u2010harmonic regression analysis approach was used to model the 24\u2010hr rhythms of <jats:styled-content style=\"fixed-case\">OPP<\/jats:styled-content> data.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>On average, a 24\u2010hr amplitude of 4.7\u00a0\u00b1\u00a02.6\u00a0mmHg was found for <jats:styled-content style=\"fixed-case\">OPP<\/jats:styled-content>. The patients were classified as either having a diurnal <jats:styled-content style=\"fixed-case\">OPP<\/jats:styled-content> rhythm (i.e. with a diurnal acrophase, 10% of the cases), a nocturnal <jats:styled-content style=\"fixed-case\">OPP<\/jats:styled-content> rhythm (45%) or absence of <jats:styled-content style=\"fixed-case\">OPP<\/jats:styled-content> rhythm (45%). Four patients had a nocturnal reduction in <jats:styled-content style=\"fixed-case\">OPP<\/jats:styled-content> (mean, \u221211%).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The physiological nocturnal rhythm of <jats:styled-content style=\"fixed-case\">OPP<\/jats:styled-content> was maintained in 45% of the <jats:styled-content style=\"fixed-case\">NAAION<\/jats:styled-content> patients. The nocturnal reduction in <jats:styled-content style=\"fixed-case\">OPP<\/jats:styled-content> seen in 20% of the patients was within the range of <jats:styled-content style=\"fixed-case\">OPP<\/jats:styled-content> where optic nerve blood flow autoregulation is still fully operative. A high prevalence of obstructive sleep apnoea syndrome in our population (71%) may explain the low frequency of systemic nocturnal hypotension.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aos.12352","type":"journal-article","created":{"date-parts":[[2014,1,25]],"date-time":"2014-01-25T07:45:20Z","timestamp":1390635920000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Twenty\u2010four\u2010hour rhythm of ocular perfusion pressure in non\u2010arteritic anterior ischaemic optic neuropathy"],"prefix":"10.1111","volume":"92","author":[{"given":"Tiffany","family":"Lacharme","sequence":"first","affiliation":[{"name":"UJF\u2010Grenoble 1 Grenoble France"},{"name":"Department of Ophthalmology CHU Grenoble Grenoble France"},{"name":"INSERM U 1042 Lab Hypoxia and Physiopathology Joseph Fourier University Grenoble France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmed","family":"Almanjoumi","sequence":"additional","affiliation":[{"name":"UJF\u2010Grenoble 1 Grenoble France"},{"name":"Department of Ophthalmology CHU Grenoble Grenoble France"},{"name":"Department of Ophthalmology King Abdulaziz University Jeddah Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Florent","family":"Aptel","sequence":"additional","affiliation":[{"name":"UJF\u2010Grenoble 1 Grenoble France"},{"name":"Department of Ophthalmology CHU Grenoble Grenoble France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hafide","family":"Khayi","sequence":"additional","affiliation":[{"name":"UJF\u2010Grenoble 1 Grenoble France"},{"name":"Department of Ophthalmology CHU Grenoble Grenoble France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean\u2010Louis","family":"Pepin","sequence":"additional","affiliation":[{"name":"UJF\u2010Grenoble 1 Grenoble France"},{"name":"INSERM U 1042 Lab Hypoxia and Physiopathology Joseph Fourier University Grenoble France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean\u2010Philippe","family":"Baguet","sequence":"additional","affiliation":[{"name":"UJF\u2010Grenoble 1 Grenoble France"},{"name":"Department of Cardiology CHU Grenoble Grenoble France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean Paul","family":"Romanet","sequence":"additional","affiliation":[{"name":"UJF\u2010Grenoble 1 Grenoble France"},{"name":"Department of Ophthalmology CHU Grenoble Grenoble France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christophe","family":"Chiquet","sequence":"additional","affiliation":[{"name":"UJF\u2010Grenoble 1 Grenoble France"},{"name":"Department of Ophthalmology CHU Grenoble Grenoble France"},{"name":"INSERM U 1042 Lab Hypoxia and Physiopathology Joseph Fourier University Grenoble France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,1,25]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.hjh.0000160207.58781.4e"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9394(14)73143-5"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2010.01.018"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1076\/ceyr.16.10.1024.9024"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/0895-7061(95)00123-7"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0702835104"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1350-9462(01)00005-2"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.preteyeres.2008.11.002"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9394(14)72557-7"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9394(14)70067-4"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1159\/000027399"},{"key":"e_1_2_5_13_1","first-page":"793","article-title":"Twenty\u2010four\u2010month update","volume":"118","author":"Ischemic Optic Neuropathy Decompression Trial","year":"2000","journal-title":"Arch Ophthalmol"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.74.2.99"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.1996.01100130562012"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1089\/108076803322279354"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.03-0757"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaophthalmol.2013.5297"},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2005.03.070"},{"key":"e_1_2_5_20_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.2005.087452"},{"key":"e_1_2_5_21_1","doi-asserted-by":"publisher","DOI":"10.1001\/archophthalmol.2010.220"},{"key":"e_1_2_5_22_1","doi-asserted-by":"publisher","DOI":"10.1006\/exer.1996.0263"},{"key":"e_1_2_5_23_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.09-3668"},{"key":"e_1_2_5_24_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00946937"},{"key":"e_1_2_5_25_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.jhh.1000808"},{"key":"e_1_2_5_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2011.04.030"},{"key":"e_1_2_5_27_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa043104"}],"container-title":["Acta Ophthalmologica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Faos.12352","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Faos.12352","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/aos.12352","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,23]],"date-time":"2023-09-23T13:40:01Z","timestamp":1695476401000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/aos.12352"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,1,25]]},"references-count":26,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2014,8]]}},"alternative-id":["10.1111\/aos.12352"],"URL":"https:\/\/doi.org\/10.1111\/aos.12352","archive":["Portico"],"relation":{},"ISSN":["1755-375X","1755-3768"],"issn-type":[{"value":"1755-375X","type":"print"},{"value":"1755-3768","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,1,25]]},"assertion":[{"value":"2013-07-23","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2013-12-10","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2014-01-25","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}