{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T20:08:07Z","timestamp":1783022887835,"version":"3.54.6"},"reference-count":30,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2014,3,26]],"date-time":"2014-03-26T00:00:00Z","timestamp":1395792000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Ophthalmologica"],"published-print":{"date-parts":[[2014,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>To evaluate plasma 25\u2010hydroxyvitamin <jats:styled-content style=\"fixed-case\">D<\/jats:styled-content> and serum total immunoglobulin E (<jats:styled-content style=\"fixed-case\">IgE<\/jats:styled-content>) levels in patients with seasonal allergic conjunctivitis (<jats:styled-content style=\"fixed-case\">SAC<\/jats:styled-content>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This observational case\u2013control study involved 49 patients with <jats:styled-content style=\"fixed-case\">SAC<\/jats:styled-content> without any other ocular and systemic diseases, and 44 consecutive, age\u2010 and sex\u2010matched healthy subjects. Plasma 25\u2010hydroxyvitamin <jats:styled-content style=\"fixed-case\">D<\/jats:styled-content> and serum total <jats:styled-content style=\"fixed-case\">IgE<\/jats:styled-content> levels of all subjects were quantified with electrochemiluminescence technique. Results were compared between the groups, and p values of &lt;0.05 were considered as statistically significant.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>No significant differences were found between the groups with respect to age (p\u00a0=\u00a00.41) and sex (p\u00a0=\u00a00.98). Plasma vitamin <jats:styled-content style=\"fixed-case\">D<\/jats:styled-content> levels of the subjects with <jats:styled-content style=\"fixed-case\">SAC<\/jats:styled-content> (median 8.03\u00a0ng\/ml, range 3.00\u201317.97\u00a0ng\/ml) were significantly lower than the control group (median 10.52\u00a0ng\/ml, range 3.30\u201325.92\u00a0ng\/ml) (p\u00a0=\u00a00.007). Serum total <jats:styled-content style=\"fixed-case\">IgE<\/jats:styled-content> levels of patients with <jats:styled-content style=\"fixed-case\">SAC<\/jats:styled-content> (median 48.65\u00a0IU\/ml, range 1.77\u2013812.00\u00a0IU\/ml) were significantly higher when compared to the control group (median 32.49\u00a0IU\/ml, range 0.14\u2013104.60\u00a0IU\/ml) (p\u00a0=\u00a00.003).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>We found lower plasma vitamin <jats:styled-content style=\"fixed-case\">D<\/jats:styled-content> levels and higher serum total <jats:styled-content style=\"fixed-case\">IgE<\/jats:styled-content> levels in patients with <jats:styled-content style=\"fixed-case\">SAC<\/jats:styled-content>.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aos.12398","type":"journal-article","created":{"date-parts":[[2014,3,26]],"date-time":"2014-03-26T05:11:37Z","timestamp":1395810697000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":26,"title":["Plasma vitamin <scp>D<\/scp> and serum total immunoglobulin <scp>E<\/scp> levels in patients with seasonal allergic conjunctivitis"],"prefix":"10.1111","volume":"92","author":[{"given":"Zeynep","family":"Dadaci","sequence":"first","affiliation":[{"name":"Department of Ophthalmology Mevlana (Rumi) University School of Medicine Meram Konya, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mehmet","family":"Borazan","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology Mevlana (Rumi) University School of Medicine Meram Konya, 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