{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T09:42:47Z","timestamp":1785577367608,"version":"3.56.0"},"reference-count":26,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2014,6,2]],"date-time":"2014-06-02T00:00:00Z","timestamp":1401667200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Ophthalmologica"],"published-print":{"date-parts":[[2014,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>To investigate the amount of endothelial cell loss (ECL) and refractive predictability by femtosecond laser\u2010assisted cataract surgery (<jats:styled-content style=\"fixed-case\">FLACS<\/jats:styled-content>) compared to conventional phacoemulsification cataract surgery (<jats:styled-content style=\"fixed-case\">CPS<\/jats:styled-content>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Forty\u2010seven patients had one eye operated by <jats:styled-content style=\"fixed-case\">FLACS<\/jats:styled-content> and the contralateral eye operated by <jats:styled-content style=\"fixed-case\">CPS<\/jats:styled-content> (stop and chop technique). Both eyes had intraocular aspheric lenses implanted. Uncorrected distance visual acuity (<jats:styled-content style=\"fixed-case\">UDVA<\/jats:styled-content>), corrected distance visual acuity (<jats:styled-content style=\"fixed-case\">CDVA<\/jats:styled-content>), central corneal endothelial cell count and hexagonality with a non\u2010contact specular microscope were assessed preoperatively, 1\u20133\u00a0days postoperatively and 3\u00a0months postoperatively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Three days postoperatively, mean <jats:styled-content style=\"fixed-case\">ECL<\/jats:styled-content> was 249\u00a0cells\/mm<jats:sup>2<\/jats:sup> (<jats:styled-content style=\"fixed-case\">SD<\/jats:styled-content>\u00a0\u00b1\u00a0744) (9.1%) by <jats:styled-content style=\"fixed-case\">FLACS<\/jats:styled-content> and 235\u00a0cells\/mm<jats:sup>2<\/jats:sup> (<jats:styled-content style=\"fixed-case\">SD<\/jats:styled-content>\u00a0\u00b1\u00a0681) (8.2%) by <jats:styled-content style=\"fixed-case\">CPS<\/jats:styled-content> (p\u00a0=\u00a00.87). Three months postoperatively, mean <jats:styled-content style=\"fixed-case\">ECL<\/jats:styled-content> was 274\u00a0cells\/mm<jats:sup>2<\/jats:sup> (<jats:styled-content style=\"fixed-case\">SD<\/jats:styled-content>\u00a0\u00b1\u00a0358) (11.4%) by <jats:styled-content style=\"fixed-case\">FLACS<\/jats:styled-content> compared with 333\u00a0cells\/mm<jats:sup>2<\/jats:sup> (<jats:styled-content style=\"fixed-case\">SD<\/jats:styled-content>\u00a0\u00b1\u00a0422) (13.9%) by <jats:styled-content style=\"fixed-case\">CPS<\/jats:styled-content>, (p\u00a0=\u00a00.30) 3\u00a0months postoperatively, hexagonality was decreased by 1.8% (<jats:styled-content style=\"fixed-case\">SD<\/jats:styled-content>\u00a0\u00b1\u00a030) by <jats:styled-content style=\"fixed-case\">FLACS<\/jats:styled-content> and by 1.4% (<jats:styled-content style=\"fixed-case\">SD<\/jats:styled-content>\u00a0\u00b1\u00a013) by <jats:styled-content style=\"fixed-case\">CPS<\/jats:styled-content>, (p\u00a0=\u00a00.84). The mean absolute difference from the attempted refraction was 0.37 dioptres (D) (<jats:styled-content style=\"fixed-case\">SD<\/jats:styled-content>\u00a0\u00b1\u00a00.33) by <jats:styled-content style=\"fixed-case\">FLACS<\/jats:styled-content> and 0.41 D (<jats:styled-content style=\"fixed-case\">SD<\/jats:styled-content>\u00a0\u00b1\u00a00.42) by <jats:styled-content style=\"fixed-case\">CPS<\/jats:styled-content> (p\u00a0=\u00a00.56). Mean <jats:styled-content style=\"fixed-case\">CDVA<\/jats:styled-content> was 0.89 (0.3; 1.25) by <jats:styled-content style=\"fixed-case\">FLACS<\/jats:styled-content> and 0.93 (0.4; 1.25) by <jats:styled-content style=\"fixed-case\">CPS<\/jats:styled-content> at 3\u00a0months postoperatively (p\u00a0=\u00a00.36). Within both groups, 70% gained a <jats:styled-content style=\"fixed-case\">CDVA<\/jats:styled-content> of 6\/6. Mean surgery time was 9.3\u00a0min (<jats:styled-content style=\"fixed-case\">SD<\/jats:styled-content>\u00a0\u00b1\u00a01.9) by <jats:styled-content style=\"fixed-case\">FLACS<\/jats:styled-content> and 8.0\u00a0min (<jats:styled-content style=\"fixed-case\">SD<\/jats:styled-content>\u00a0\u00b1\u00a01.9) by <jats:styled-content style=\"fixed-case\">CPS<\/jats:styled-content>, (p\u00a0=\u00a00.0018). Mean phaco energy was 3.78\u00a0U\/S (<jats:styled-content style=\"fixed-case\">SD<\/jats:styled-content>\u00a0\u00b1\u00a05.1) and 5.45\u00a0U\/S (<jats:styled-content style=\"fixed-case\">SD<\/jats:styled-content>\u00a0\u00b1\u00a04.6) (p\u00a0&lt;\u00a00.0001) by <jats:styled-content style=\"fixed-case\">FLACS<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">CPS<\/jats:styled-content>, respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>We found no significant difference in <jats:styled-content style=\"fixed-case\">ECL<\/jats:styled-content> and refractive predictability between <jats:styled-content style=\"fixed-case\">FLACS<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">CPS<\/jats:styled-content> 3\u00a0months 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