{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T13:46:58Z","timestamp":1787060818065,"version":"build-2736575974"},"reference-count":40,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2014,5,22]],"date-time":"2014-05-22T00:00:00Z","timestamp":1400716800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/3.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Ophthalmologica"],"published-print":{"date-parts":[[2015,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>\n                      To study ocular characteristics in 87 patients with verified Marfan syndrome (\n                      <jats:styled-content style=\"fixed-case\">MFS<\/jats:styled-content>\n                      ) based on the Ghent criteria from 1996 (Ghent\u20101).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      The position of the lens was noted by observing the eye in different gaze directions in maximal mydriasis during slit lamp examination. Ectopia lentis (\n                      <jats:styled-content style=\"fixed-case\">EL<\/jats:styled-content>\n                      ) was classified as subluxated (dislocation slightly backwards) or luxated (vertical or horizontal displacement). Corneal curvature, axial length (\n                      <jats:styled-content style=\"fixed-case\">AL<\/jats:styled-content>\n                      ), corneal diameter, central corneal thickness, anterior chamber depth, lens thickness, condition of the iris, intraocular pressure, spherical equivalent and visual acuity were also investigated.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      <jats:styled-content style=\"fixed-case\">EL<\/jats:styled-content>\n                      was found in 108 eyes (62.1%). Of the 68 phakic eyes with\n                      <jats:styled-content style=\"fixed-case\">EL<\/jats:styled-content>\n                      , 43 (63.2%) had subluxation. Mean\n                      <jats:styled-content style=\"fixed-case\">AL<\/jats:styled-content>\n                      was 24.80\u00a0\u00b1\u00a02.57\u00a0mm, and the\n                      <jats:styled-content style=\"fixed-case\">AL<\/jats:styled-content>\n                      was above 23.5\u00a0mm in 65.3%. Mean keratometry (K) in phakic eyes was 41.79\u00a0\u00b1\u00a01.70 diopters (D), and the K value was &lt;41.5D in 46.8%. Iris hypoplasia was found in 3.4%. Myopia above 3D occurred in 38.4% of the phakic eyes. Mean binocular log\n                      <jats:styled-content style=\"fixed-case\">MAR<\/jats:styled-content>\n                      was 0.10\u00a0\u00b1\u00a00.32. Only five patients (5.7%) had a log\n                      <jats:styled-content style=\"fixed-case\">MAR<\/jats:styled-content>\n                      more than 0.5. These 5 patients had\n                      <jats:styled-content style=\"fixed-case\">EL<\/jats:styled-content>\n                      , and 4 of them were amblyopic.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      In this strictly defined\n                      <jats:styled-content style=\"fixed-case\">MFS<\/jats:styled-content>\n                      group fulfilling the Ghent\u20101 criteria, the prevalence of\n                      <jats:styled-content style=\"fixed-case\">EL<\/jats:styled-content>\n                      was 62.1%. In many cases, the dislocation of the lens was subtle. On average, the corneas were flattened and the globe length was increased. Only a few patients were visually impaired. Children with\n                      <jats:styled-content style=\"fixed-case\">MFS<\/jats:styled-content>\n                      should have a thorough follow up to avoid amblyopia.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/aos.12448","type":"journal-article","created":{"date-parts":[[2014,5,22]],"date-time":"2014-05-22T23:41:10Z","timestamp":1400802070000},"page":"46-53","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":57,"title":["Ocular findings in 87 adults with Ghent\u20101 verified Marfan syndrome"],"prefix":"10.1111","volume":"93","author":[{"given":"Liv","family":"Drolsum","sequence":"first","affiliation":[{"name":"Department of Ophthalmology Oslo University Hospital Oslo Norway"},{"name":"University of Oslo Oslo Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Svend","family":"Rand\u2010Hendriksen","sequence":"additional","affiliation":[{"name":"University 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