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This systematic review and meta\u2010analysis is focused on presenting the evidence concerning progression of <jats:styled-content style=\"fixed-case\">AMD<\/jats:styled-content> in patients undergoing cataract surgery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We performed a systematic literature search in the <jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>ub<jats:styled-content style=\"fixed-case\">M<\/jats:styled-content>ed, <jats:styled-content style=\"fixed-case\">M<\/jats:styled-content>edline, <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>ochrane <jats:styled-content style=\"fixed-case\">L<\/jats:styled-content>ibrary and <jats:styled-content style=\"fixed-case\">CINAHL<\/jats:styled-content> databases. Two randomized trials and two case\u2013control trials were identified. Quality of the studies was assessed using the Cochrane risk of bias tool, data were extracted, and meta\u2010analyses were performed. Quality of the available evidence was evaluated using the <jats:styled-content style=\"fixed-case\">GRADE<\/jats:styled-content> system.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>We found that visual acuity at 6\u201312\u00a0months follow\u2010up was significantly better (6.5\u20137.5 letters) in eyes that had undergone cataract surgery than in unoperated eyes, but the included number of subjects was small, and hence, the quality of evidence was downgraded to moderate. We did not find an increased risk of progression to exudative <jats:styled-content style=\"fixed-case\">AMD<\/jats:styled-content> 6\u201312\u00a0months after cataract surgery [<jats:styled-content style=\"fixed-case\">RR<\/jats:styled-content> 3.21 (0.14\u201375.68)], but the included number of subjects was small, and thus, the quality of the evidence was moderate.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Cataract surgery increases visual acuity without an increased risk of progression to exudative <jats:styled-content style=\"fixed-case\">AMD<\/jats:styled-content>, but further research with longer follow\u2010up is encouraged.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aos.12665","type":"journal-article","created":{"date-parts":[[2015,1,20]],"date-time":"2015-01-20T07:17:55Z","timestamp":1421738275000},"page":"593-600","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":43,"title":["Cataract surgery and age\u2010related macular degeneration. 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