{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,21]],"date-time":"2026-01-21T16:47:58Z","timestamp":1769014078724,"version":"3.49.0"},"reference-count":26,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2015,2,26]],"date-time":"2015-02-26T00:00:00Z","timestamp":1424908800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100004587","name":"Instituto de Salud Carlos III","doi-asserted-by":"crossref","award":["PI08\/0602"],"award-info":[{"award-number":["PI08\/0602"]}],"id":[{"id":"10.13039\/501100004587","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Ophthalmologica"],"published-print":{"date-parts":[[2015,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>To evaluate possible changes in corneal hysteresis (<jats:styled-content style=\"fixed-case\">CH<\/jats:styled-content>) after topical treatment with a prostaglandin analogue in medication\u2010na\u00efve eyes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This was a prospective, observational cohort study. Sixty\u2010eight eyes of 68 patients were prospectively included who were newly diagnosed with primary open\u2010angle glaucoma or ocular hypertension in our institution. All patients were treatment\u2010na\u00efve. Patients were evaluated at baseline and after 6\u00a0months of treatment with latanoprost in the eye with the lower intraocular pressure (<jats:styled-content style=\"fixed-case\">IOP<\/jats:styled-content>) measured by Goldmann applanation tonometry (<jats:styled-content style=\"fixed-case\">GAT<\/jats:styled-content>). The ocular response analyzer was used to measure <jats:styled-content style=\"fixed-case\">CH<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>CH increased significantly (p<jats:italic>\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.0001) from 8.96\u00a0\u00b1\u00a02.3\u00a0mmHg to 9.79\u00a0\u00b1\u00a01.97\u00a0mmHg, and this increase was correlated significantly (p<jats:italic>\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.0001, <jats:italic>r<\/jats:italic>\u00a0=\u00a00.64, <jats:italic>r<\/jats:italic><jats:sup>2<\/jats:sup>\u00a0=\u00a00.41) with the basal <jats:styled-content style=\"fixed-case\">CH<\/jats:styled-content>. We identified a weak but significant (<jats:italic>r<\/jats:italic><jats:sup>2<\/jats:sup>\u00a0=\u00a00.06, p<jats:italic>\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.01) relationship between the basal <jats:styled-content style=\"fixed-case\">CH<\/jats:styled-content> and the drug\u2010induced reduction of the <jats:styled-content style=\"fixed-case\">GAT IOP<\/jats:styled-content>. Nevertheless, the increase in the drug\u2010induced <jats:styled-content style=\"fixed-case\">CH<\/jats:styled-content> was not correlated with the decrease in the <jats:styled-content style=\"fixed-case\">GAT IOP<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Treatment with latanoprost increases <jats:styled-content style=\"fixed-case\">CH<\/jats:styled-content>. The <jats:styled-content style=\"fixed-case\">CH<\/jats:styled-content> increase was not correlated with the drug\u2010induced decrease in the <jats:styled-content style=\"fixed-case\">GAT IOP<\/jats:styled-content>, which suggested a direct effect of latanoprost on the viscoelastic corneal properties.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aos.12689","type":"journal-article","created":{"date-parts":[[2015,2,27]],"date-time":"2015-02-27T01:22:18Z","timestamp":1425000138000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":49,"title":["Effect of topical prostaglandin analogues on corneal hysteresis"],"prefix":"10.1111","volume":"93","author":[{"given":"Gema","family":"Bol\u00edvar","sequence":"first","affiliation":[{"name":"Universitary Hospital \u201cPr\u00edncipe de Asturias\u201d Alcal\u00e1 de Henares Madrid Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cristina","family":"S\u00e1nchez\u2010Barahona","sequence":"additional","affiliation":[{"name":"Universitary Hospital \u201cPr\u00edncipe de Asturias\u201d Alcal\u00e1 de Henares Madrid Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miguel","family":"Teus","sequence":"additional","affiliation":[{"name":"Universitary Hospital \u201cPr\u00edncipe de Asturias\u201d Alcal\u00e1 de Henares Madrid Spain"},{"name":"University of Alcal\u00e1 Alcal\u00e1 de Henares Madrid Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miguel A.","family":"Castej\u00f3n","sequence":"additional","affiliation":[{"name":"Universitary Hospital \u201cPr\u00edncipe de Asturias\u201d Alcal\u00e1 de Henares Madrid Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Javier","family":"Paz\u2010Moreno\u2010Arrones","sequence":"additional","affiliation":[{"name":"Universitary Hospital \u201cPr\u00edncipe de Asturias\u201d Alcal\u00e1 de Henares Madrid Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Consuelo","family":"Guti\u00e9rrez\u2010Ortiz","sequence":"additional","affiliation":[{"name":"Universitary Hospital \u201cPr\u00edncipe de Asturias\u201d Alcal\u00e1 de Henares Madrid Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dimitrios G.","family":"Mikropoulos","sequence":"additional","affiliation":[{"name":"3rd University Department of Ophthalmology Aristotle University Thessaloniki Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,2,26]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9394(99)00349-9"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.2010.196899"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.10-5580"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/IJG.0b013e3181ca7c7a"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.3109\/02713683.2011.608239"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2005.12.007"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/IJG.0b013e3182071b92"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0039-6257(00)00110-7"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.119.8.1165"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.06-0014"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/ICO.0b013e31802e3ce4"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1001\/archophthalmol.2010.40"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-5155(02)00667-6"},{"key":"e_1_2_5_15_1","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1097\/IJG.0b013e3181aff419","article-title":"Modifications in corneal biomechanics and intraocular pressure after deep sclerectomy","volume":"19","author":"Iordanidou V","year":"2010","journal-title":"J Glaucoma"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9394(98)00438-3"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.06-0334"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.3109\/02713683.2013.801495"},{"key":"e_1_2_5_19_1","doi-asserted-by":"crossref","DOI":"10.1007\/978-0-387-76700-0","volume-title":"The glaucoma book. 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