{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,23]],"date-time":"2026-04-23T08:04:34Z","timestamp":1776931474940,"version":"3.51.2"},"reference-count":19,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2015,2,23]],"date-time":"2015-02-23T00:00:00Z","timestamp":1424649600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31271022"],"award-info":[{"award-number":["31271022"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Ophthalmologica"],"published-print":{"date-parts":[[2016,6]]},"abstract":"Abstract<\/jats:title>Purpose<\/jats:title>To compare subtenon triamcinolone versus systemic dexamethasone for perisurgical management of primary rhegmatogenous retinal detachment presenting with a choroidal detachment (RRD<\/jats:styled-content>\/CD<\/jats:styled-content>).<\/jats:p><\/jats:sec>Methods<\/jats:title>Thirty consecutive primary RRD<\/jats:styled-content>\/CD<\/jats:styled-content> patients were prospectively studied. Sixteen RRD<\/jats:styled-content>\/CD<\/jats:styled-content> patients were injected with a 40\u00a0mg subtenon triamcinolone acetonide (TA<\/jats:styled-content>) 5\u00a0days before a scheduled vitrectomy (TA<\/jats:styled-content> group) while the other 14 RRD<\/jats:styled-content>\/CD<\/jats:styled-content> patients were intravenously infused daily with 10\u00a0mg dexamethasone (Dex) for 5\u00a0days before a scheduled vitrectomy (Dex group). All patients were followed up for 6\u00a0months. Changes of choroid detachment on B ultrasonography and preoperative intraocular pressure (IOP<\/jats:styled-content>), systemic and ocular steroid level, blood sugar, and postoperative macular oedema were compared between the two groups.<\/jats:p><\/jats:sec>Results<\/jats:title>During 5\u00a0days of presurgical treatment, the IOP<\/jats:styled-content> recovery from the baseline was 3.29\u00a0\u00b1\u00a04.56\u00a0mmHg for the TA<\/jats:styled-content> group versus 1.16\u00a0\u00b1\u00a01.60\u00a0mmHg for the Dex group (p\u00a0=\u00a00.021). The height of CD<\/jats:styled-content> decreased significantly more for the TA<\/jats:styled-content> group (3.55\u00a0\u00b1\u00a01.33 versus 1.84\u00a0\u00b1\u00a01.5\u00a0mm, p\u00a0=\u00a00.0029). The physiological cortisol level in the plasma was significantly suppressed for the Dex group (8.35\u00a0\u00b1\u00a010.35 versus 51.9\u00a0\u00b1\u00a035.9\u00a0ng\/ml, p\u00a0=\u00a00.01). Postoperative 1\u2010month macula was less oedematous for TA<\/jats:styled-content> group (401\u00a0\u00b1\u00a0196 versus 256\u00a0\u00b1\u00a066\u00a0\u03bc<\/jats:italic>m, p\u00a0=\u00a00.0498).<\/jats:p><\/jats:sec>Conclusion<\/jats:title>Subtenon TA<\/jats:styled-content> seems to be a better option for perisurgical management of RRD<\/jats:styled-content>\/CD<\/jats:styled-content> patients than systemic steroid application. Subtenon TA<\/jats:styled-content> is more convenient for patients and imposes much less stress to patients\u2019 hormones homeostasis. This is especially important for those who are suffering metabolic disorders and need vitrectomy surgery for repairing RRD<\/jats:styled-content>\/CD<\/jats:styled-content>.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aos.12694","type":"journal-article","created":{"date-parts":[[2015,2,24]],"date-time":"2015-02-24T01:31:34Z","timestamp":1424741494000},"page":"391-396","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Perioperative pharmacological management of choroidal detachment associated with rhegmatogenous retinal detachment"],"prefix":"10.1111","volume":"94","author":[{"given":"Lijun","family":"Shen","sequence":"first","affiliation":[{"name":"Eye Hospital and School of Ophthalmology and Optometry Wenzhou Medical University Wenzhou Zhejiang China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jianbo","family":"Mao","sequence":"additional","affiliation":[{"name":"Eye Hospital and School of 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