{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,22]],"date-time":"2026-06-22T22:50:58Z","timestamp":1782168658193,"version":"3.54.5"},"reference-count":41,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2015,4,27]],"date-time":"2015-04-27T00:00:00Z","timestamp":1430092800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Ophthalmologica"],"published-print":{"date-parts":[[2015,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>To evaluate the nocturnal blood pressure (<jats:styled-content style=\"fixed-case\">BP<\/jats:styled-content>) dipping\u2010pattern in patients with manifest primary open\u2010angle glaucoma (<jats:styled-content style=\"fixed-case\">POAG<\/jats:styled-content>) and to find possible associations with the severity of visual field damage.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A number of 314 patients suffering from <jats:styled-content style=\"fixed-case\">POAG<\/jats:styled-content> were consecutively enrolled in this cross\u2010sectional hospital\u2010based study. Each patient had diurnal intraocular pressure (<jats:styled-content style=\"fixed-case\">IOP<\/jats:styled-content>) measurements, 24\u2010hr <jats:styled-content style=\"fixed-case\">BP<\/jats:styled-content> monitoring and computerized perimetry with the Humphrey 30\u20102 <jats:sc>sita<\/jats:sc> Standard program. Inclusion criteria were a mean <jats:styled-content style=\"fixed-case\">IOP<\/jats:styled-content> of less than 15\u00a0mmHg with fluctuations of less than 5\u00a0mmHg and a visual acuity of at least 20\/40. One eye was randomly selected. Based on the night\u2013day <jats:styled-content style=\"fixed-case\">BP<\/jats:styled-content> ratio, a mean arterial nocturnal <jats:styled-content style=\"fixed-case\">BP<\/jats:styled-content> drop of less than 10% was considered as non\u2010dipping, between 10% and 20% as physiological dipping and of more than 20% as over\u2010dipping.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Glaucoma patients with daytime systemic normotension on the average had more visual field loss in the over\u2010dipper group (<jats:styled-content style=\"fixed-case\">MD<\/jats:styled-content>\u00a0=\u00a0\u2212\u00a016.6\u00a0<jats:styled-content style=\"fixed-case\">dB<\/jats:styled-content>,<jats:styled-content style=\"fixed-case\"> IQR<\/jats:styled-content>\u00a0=\u00a0\u221218.9 to \u22122.7\u00a0dB) than glaucoma patients with daytime systemic hypertension, who had less visual field defects in the over\u2010dipper group (<jats:styled-content style=\"fixed-case\">MD<\/jats:styled-content>\u00a0=\u00a0\u22123.9\u00a0<jats:styled-content style=\"fixed-case\">dB<\/jats:styled-content>,<jats:styled-content style=\"fixed-case\"> IQR<\/jats:styled-content>\u00a0=\u00a0\u22126.2 to \u22121.9\u00a0dB) (p\u00a0=\u00a00.004). This result was also found taking age, glaucoma duration, visual acuity, gender, systemic and topical medication as covariates into account.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>To judge the nocturnal <jats:styled-content style=\"fixed-case\">BP<\/jats:styled-content> situation of an individual patient, it is important to do this in relation to the daytime <jats:styled-content style=\"fixed-case\">BP<\/jats:styled-content> level. Twenty\u2010four\u2010hour <jats:styled-content style=\"fixed-case\">BP<\/jats:styled-content> evaluation might be important for all patients with <jats:styled-content style=\"fixed-case\">POAG<\/jats:styled-content>, as nocturnal <jats:styled-content style=\"fixed-case\">BP<\/jats:styled-content> could be a modifiable risk factor for glaucoma severity and progression.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aos.12740","type":"journal-article","created":{"date-parts":[[2015,4,27]],"date-time":"2015-04-27T08:32:42Z","timestamp":1430123562000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":33,"title":["Nocturnal blood pressure in primary open\u2010angle glaucoma"],"prefix":"10.1111","volume":"93","author":[{"given":"Karin R.","family":"Pillunat","sequence":"first","affiliation":[{"name":"Department of Ophthalmology University Hospital Carl Gustav Carus TU Dresden Dresden 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