{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T21:58:42Z","timestamp":1773179922143,"version":"3.50.1"},"reference-count":38,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2015,6,14]],"date-time":"2015-06-14T00:00:00Z","timestamp":1434240000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"CNUH Biomedical Research Institute","award":["CRI 13906-22"],"award-info":[{"award-number":["CRI 13906-22"]}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Ophthalmologica"],"published-print":{"date-parts":[[2016,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>To compare the effects of ketorolac 0.45% and diclofenac 0.1% on macular thickness and volume after uncomplicated cataract surgery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A total of 76 eyes of 76 patients who underwent uncomplicated cataract surgery were included. Patients were treated with either diclofenac 0.1% (38 eyes) or ketorolac 0.45% (38 eyes) after surgery. The macular thickness and volume were obtained with optical coherence tomography (<jats:styled-content style=\"fixed-case\">OCT<\/jats:styled-content>). Central subfield thickness (<jats:styled-content style=\"fixed-case\">CST<\/jats:styled-content>,<jats:styled-content style=\"fixed-case\"> OCT<\/jats:styled-content> 1\u00a0mm zone), total foveal thickness (<jats:styled-content style=\"fixed-case\">TFT<\/jats:styled-content>,<jats:styled-content style=\"fixed-case\"> OCT<\/jats:styled-content> 3\u00a0mm zone), total macular thickness (<jats:styled-content style=\"fixed-case\">TMT<\/jats:styled-content>,<jats:styled-content style=\"fixed-case\"> OCT<\/jats:styled-content> 6\u00a0mm zone), average macular thickness (AMT) and total macular volume (<jats:styled-content style=\"fixed-case\">TMV<\/jats:styled-content>) were compared between the two study groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>No significant differences between groups were found in macular thickness or volume 1\u00a0month after cataract surgery. Two months after surgery, the ketorolac group had significantly lower <jats:styled-content style=\"fixed-case\">CST<\/jats:styled-content>,<jats:styled-content style=\"fixed-case\"> TFT<\/jats:styled-content>,<jats:styled-content style=\"fixed-case\"> TMT<\/jats:styled-content> and AMT than the diclofenac group (p\u00a0&lt;\u00a00.05 for all). Additionally, 1 and 2\u00a0months after surgery, changes from preoperative values in <jats:styled-content style=\"fixed-case\">CST<\/jats:styled-content> (both p\u00a0=\u00a00.04), AMT (p\u00a0=\u00a00.02 and p\u00a0&lt;\u00a00.01, respectively) and <jats:styled-content style=\"fixed-case\">TMV<\/jats:styled-content> (both p\u00a0=\u00a00.04) were significantly less in the ketorolac group than in the diclofenac group.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Following uncomplicated cataract surgery, topical ketorolac 0.45% was more effective than diclofenac 0.1% in preventing increases in macular thickness and volume.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aos.12780","type":"journal-article","created":{"date-parts":[[2015,6,15]],"date-time":"2015-06-15T01:20:32Z","timestamp":1434331232000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Comparison of ketorolac 0.45% versus diclofenac 0.1% for macular thickness and volume after uncomplicated cataract surgery"],"prefix":"10.1111","volume":"94","author":[{"given":"Tae Hee","family":"Lee","sequence":"first","affiliation":[{"name":"Department of Ophthalmology Chonnam National University Medical School and Hospital Gwangju South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Won","family":"Choi","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology Chonnam National University Medical School and Hospital Gwangju South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yong Sok","family":"Ji","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology Chonnam National University Medical School and Hospital Gwangju South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kyung Chul","family":"Yoon","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology Chonnam National University Medical School and Hospital Gwangju South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,6,14]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.2147\/OPTH.S15146"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.eye.6702460"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02265118"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12325-011-0080-7"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.3109\/02713680903288937"},{"key":"e_1_2_5_7_1","first-page":"265","article-title":"Macular image changes of optical coherence tomography after phacoemulsification","volume":"38","author":"Cheng B","year":"2002","journal-title":"Zhonghua Yan Ke Za Zhi"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.eye.6701864"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.3341\/jkos.2010.51.7.935"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2010.09.003"},{"key":"e_1_2_5_11_1","first-page":"557","article-title":"The incidence, pathogenesis and treatment of cystoid macular edema following cataract surgery","volume":"96","author":"Flach AJ","year":"1998","journal-title":"Trans Am Ophthalmol Soc"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/00004397-200201000-00003"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(90)32423-5"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1755-3768.2010.01896.x"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.3129\/i06-062"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.1985.01050080046017"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2014.04.035"},{"key":"e_1_2_5_18_1","first-page":"1827","article-title":"Improved ocular: systemic absorption ratio of timolol by viscous vehicle and phenylephrine","volume":"31","author":"Kyyronen K","year":"1990","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0886-3350(03)00582-0"},{"key":"e_1_2_5_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2009.12.010"},{"key":"e_1_2_5_21_1","first-page":"819","article-title":"The relation between expression of vascular endothelial growth factor and breakdown of the blood\u2010retinal barrier in diabetic rat retinas","volume":"74","author":"Murata T","year":"1996","journal-title":"Lab Invest"},{"key":"e_1_2_5_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1442-9071.2006.01169.x"},{"key":"e_1_2_5_23_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4615-5359-5_107"},{"key":"e_1_2_5_24_1","doi-asserted-by":"publisher","DOI":"10.1080\/02713680601160610"},{"key":"e_1_2_5_25_1","doi-asserted-by":"publisher","DOI":"10.1076\/soph.17.3.167.14794"},{"key":"e_1_2_5_26_1","first-page":"751","article-title":"Critical appraisal of ophthalmic ketorolac in treatment of pain and inflammation following cataract surgery","volume":"5","author":"Reddy R","year":"2011","journal-title":"Clin Ophthalmol"},{"key":"e_1_2_5_27_1","first-page":"544","article-title":"Macular changes secondary to vitreous traction","volume":"64","author":"Reese AB","year":"1967","journal-title":"Trans Am J Ophthalmol Soc"},{"key":"e_1_2_5_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0886-3350(03)00233-5"},{"key":"e_1_2_5_29_1","doi-asserted-by":"publisher","DOI":"10.1097\/00055735-200002000-00010"},{"key":"e_1_2_5_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(98)93018-4"},{"key":"e_1_2_5_31_1","first-page":"190","article-title":"Visual outcome in pseudophakic eyes with clinical cystoid macular edema","volume":"22","author":"Ruiz RS","year":"1991","journal-title":"Ophthalmic Surg"},{"key":"e_1_2_5_32_1","doi-asserted-by":"publisher","DOI":"10.1248\/bpb.23.1352"},{"key":"e_1_2_5_33_1","doi-asserted-by":"publisher","DOI":"10.1159\/000068563"},{"key":"e_1_2_5_34_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaophthalmol.2013.5692"},{"key":"e_1_2_5_35_1","doi-asserted-by":"publisher","DOI":"10.1517\/17425240903116006"},{"key":"e_1_2_5_36_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.2005.073817"},{"key":"e_1_2_5_37_1","doi-asserted-by":"publisher","DOI":"10.1185\/030079906X112471"},{"key":"e_1_2_5_38_1","doi-asserted-by":"publisher","DOI":"10.1089\/jop.2010.0135"},{"key":"e_1_2_5_39_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00414576"}],"container-title":["Acta Ophthalmologica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Faos.12780","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/aos.12780","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,24]],"date-time":"2023-09-24T09:38:45Z","timestamp":1695548325000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/aos.12780"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,6,14]]},"references-count":38,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2016,5]]}},"alternative-id":["10.1111\/aos.12780"],"URL":"https:\/\/doi.org\/10.1111\/aos.12780","archive":["Portico"],"relation":{},"ISSN":["1755-375X","1755-3768"],"issn-type":[{"value":"1755-375X","type":"print"},{"value":"1755-3768","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,6,14]]},"assertion":[{"value":"2015-02-15","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2015-05-11","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2015-06-14","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}