{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T22:32:01Z","timestamp":1783636321971,"version":"3.55.0"},"reference-count":34,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2015,10,28]],"date-time":"2015-10-28T00:00:00Z","timestamp":1445990400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Sivas Provincial Management of Public Health and Sivas Association of Public Hospitals Management"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Ophthalmologica"],"published-print":{"date-parts":[[2016,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>To investigate the prevalence of the exfoliation syndrome and its relationship with ocular and cardiovascular diseases in the Central Anatolia region of Turkey.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This cross\u2010sectional and population\u2010based study was conducted at the Sivas Province among the population aged 40\u00a0years and over. The diagnosis of <jats:styled-content style=\"fixed-case\">XFS<\/jats:styled-content> was made when exfoliative material was found on the anterior lens capsule or iris on slit\u2010lamp examination. The subjects were divided into an <jats:styled-content style=\"fixed-case\">XFS<\/jats:styled-content> group and a non\u2010<jats:styled-content style=\"fixed-case\">XFS<\/jats:styled-content> group according to the presence of exfoliative material, and the groups were compared for the presence of glaucoma, cataract, age\u2010related macular degeneration, phacodonesis, hypertension, diabetes mellitus, coronary artery disease, smoking and alcohol\u2010use frequency.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">XFS<\/jats:styled-content> was present in 63 subjects consisting of 42 males (8.0%) and 21 females (3.6%) for an overall rate of 5.7% (95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>: 0.054\u20130.060). Once we adjusted the values for age, we found a statistically significant relationship of increased age and male gender with the presence of <jats:styled-content style=\"fixed-case\">XFS<\/jats:styled-content> (p\u00a0=\u00a00.001, p\u00a0=\u00a00.027, respectively). The relationship between <jats:styled-content style=\"fixed-case\">XFS<\/jats:styled-content> and glaucoma, cataract and phacodonesis was found to be statistically significant (p\u00a0=\u00a00.001). No relationship was found between exfoliation syndrome and hypertension, diabetes mellitus and coronary artery disease.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The prevalence of exfoliation syndrome was 5.7% in this population\u2010based study. There was a statistically significant relationship between <jats:styled-content style=\"fixed-case\">XFS<\/jats:styled-content> and advancing age and male gender.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aos.12885","type":"journal-article","created":{"date-parts":[[2015,10,28]],"date-time":"2015-10-28T11:38:14Z","timestamp":1446032294000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["The prevalence of exfoliation syndrome in Turkey"],"prefix":"10.1111","volume":"94","author":[{"given":"Ra\u015fit","family":"K\u0131l\u0131\u00e7","sequence":"first","affiliation":[{"name":"Department of Ophthalmology Sivas Numune Hospital Sivas Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naim","family":"Karag\u00f6z","sequence":"additional","affiliation":[{"name":"Department of Medical Education Faculty of Medicine Cumhuriyet University Sivas 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