{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T14:24:16Z","timestamp":1787495056090,"version":"build-2736575974"},"reference-count":19,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2015,12,9]],"date-time":"2015-12-09T00:00:00Z","timestamp":1449619200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81300746"],"award-info":[{"award-number":["81300746"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Ophthalmologica"],"published-print":{"date-parts":[[2016,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>\n                      To evaluate the efficacy and complications of black diaphragm intra\u2010ocular (\n                      <jats:styled-content style=\"fixed-case\">BDI<\/jats:styled-content>\n                      ) lens implantation in patients with congenital aniridia.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Twenty patients underwent\n                      <jats:styled-content style=\"fixed-case\">BDI<\/jats:styled-content>\n                      lens implantation for the treatment of congenital aniridia from January 1999 to December 2012. Fifteen patients (23 eyes) were enrolled in our study, and the mean follow\u2010up period was 26\u00a0months. Patient demographics, clinical evaluations [visual acuity (\n                      <jats:styled-content style=\"fixed-case\">VA<\/jats:styled-content>\n                      ), best\u2010corrected visual acuity (\n                      <jats:styled-content style=\"fixed-case\">BCVA<\/jats:styled-content>\n                      ), intra\u2010ocular pressure measurement (\n                      <jats:styled-content style=\"fixed-case\">IOP<\/jats:styled-content>\n                      ), corneal endothelial cell density (\n                      <jats:styled-content style=\"fixed-case\">ECD<\/jats:styled-content>\n                      ) and ultrasound biomicroscopy (\n                      <jats:styled-content style=\"fixed-case\">UBM<\/jats:styled-content>\n                      )], complications and treatments were analysed for each patient.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Sixteen eyes (70.1%) had a\n                      <jats:styled-content style=\"fixed-case\">BCVA<\/jats:styled-content>\n                      better than 20\/200 after\n                      <jats:styled-content style=\"fixed-case\">BDI<\/jats:styled-content>\n                      lens implantation, and photophobia obviously decreased in all patients. Six eyes (26.09%) developed secondary glaucoma after\n                      <jats:styled-content style=\"fixed-case\">BDI<\/jats:styled-content>\n                      lens implantation, and one eye underwent glaucoma surgery. Corneal decompensation occurred in two eyes (8.70%), one of which was complicated by glaucoma. Two eyes (8.70%) developed visual axis opacity (\n                      <jats:styled-content style=\"fixed-case\">VAO<\/jats:styled-content>\n                      ) after surgery. One patient (4.35%) had limbal stem cell failure, and another patient (4.35%) had an eccentric\n                      <jats:styled-content style=\"fixed-case\">BDI<\/jats:styled-content>\n                      lens. Intra\u2010ocular pressure measurement elevation and\n                      <jats:styled-content style=\"fixed-case\">ECD<\/jats:styled-content>\n                      reduction were found after\n                      <jats:styled-content style=\"fixed-case\">BDI<\/jats:styled-content>\n                      lens implantation.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      Black diaphragm intra\u2010ocular lens implantation can effectively improve\n                      <jats:styled-content style=\"fixed-case\">VA<\/jats:styled-content>\n                      , decrease photophobia and resolve cosmetic issues in most congenital aniridia eyes. Glaucoma, corneal decompensation and\n                      <jats:styled-content style=\"fixed-case\">VAO<\/jats:styled-content>\n                      were the major long\u2010term complications of\n                      <jats:styled-content style=\"fixed-case\">BDI<\/jats:styled-content>\n                      lens implantation in patients with congenital aniridia. All patients should be managed attentively because of high risk of complications and followed long term to achieve favourable outcomes.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/aos.12923","type":"journal-article","created":{"date-parts":[[2015,12,9]],"date-time":"2015-12-09T12:59:18Z","timestamp":1449665958000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["The efficacy and complications of black diaphragm intra\u2010ocular lens implantation in patients with congenital aniridia"],"prefix":"10.1111","volume":"94","author":[{"given":"Xiaodi","family":"Qiu","sequence":"first","affiliation":[{"name":"Department of Ophthalmology Eye and ENT Hospital of Fudan University Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yinghong","family":"Ji","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology Eye and ENT Hospital of Fudan University Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tianyu","family":"Zheng","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology Eye and ENT Hospital of Fudan University Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi","family":"Lu","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology Eye and ENT Hospital of Fudan University Shanghai 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