{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T03:52:13Z","timestamp":1793332333531,"version":"4.5.0"},"reference-count":9,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2016,4,1]],"date-time":"2016-04-01T00:00:00Z","timestamp":1459468800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Ophthalmologica"],"published-print":{"date-parts":[[2016,11]]},"abstract":"Abstract<\/jats:title>Purpose<\/jats:title>To compare the outcome of primary trabeculotomy with that of combined trabeculectomy\u2013trabeculotomy (CTT<\/jats:styled-content>) with mitomycin C (MMC<\/jats:styled-content>) in children with congenital glaucoma.<\/jats:p><\/jats:sec>Methods<\/jats:title>This is a prospective comparative study, carried out on a cohort of 28 eyes (28 infants) with congenital glaucoma. Infants with proved congenital glaucoma [based on intra\u2010ocular pressure (IOP<\/jats:styled-content>), cup\/disc (C\/D ratio), corneal diameter and axial length measurements] were randomly allocated to either group A (trabeculotomy) or group B (CTT<\/jats:styled-content> with MMC<\/jats:styled-content>). Postoperatively, all patients were followed regularly for 3\u00a0years; for IOP<\/jats:styled-content> and C\/D evaluation. Criteria for successful outcome included resolution of corneal oedema, reversal of disc cupping, and IOP<\/jats:styled-content> 18\u00a0mmHg or less.<\/jats:p><\/jats:sec>Results<\/jats:title>Success rate in each group was 85.7% (p\u00a0=\u00a01.00). All preoperative parameters, including horizontal corneal diameter, axial length, IOP<\/jats:styled-content> and C\/D ratio, were not statistically significantly different between the two groups. Also, postoperative C\/D ratio, IOP<\/jats:styled-content>, IOP<\/jats:styled-content> difference and percentage difference (compared to preoperative values), at different follow\u2010up visits, were not statistically significantly different between both surgical techniques. Comparing preoperative to postoperative IOP<\/jats:styled-content> and C\/D ratio in each group was statistically significant.<\/jats:p><\/jats:sec>Conclusion<\/jats:title>Both primary trabeculotomy and CTT<\/jats:styled-content> with MMC<\/jats:styled-content> had similar outcomes, which could mean that trabeculotomy could be resorted to first.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aos.13018","type":"journal-article","created":{"date-parts":[[2016,4,2]],"date-time":"2016-04-02T18:53:59Z","timestamp":1459623239000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":28,"title":["Primary trabeculotomy compared to combined trabeculectomy\u2013trabeculotomy in congenital glaucoma: 3\u2010year study"],"prefix":"10.1111","volume":"94","author":[{"given":"Dalia H.","family":"Khalil","sequence":"first","affiliation":[{"name":"Department of Ophthalmology Kasr Al\u2010Ainy Hospital Cairo University Cairo Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamad A. S. E.","family":"Abdelhakim","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology Kasr Al\u2010Ainy Hospital Cairo University Cairo Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,4]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.2004.047761"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.73.8.608"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.78.10.745"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/aos.12634"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(03)00671-7"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9394(83)90260-X"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.eye.6702850"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/aos.12834"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/aos.12566"}],"container-title":["Acta Ophthalmologica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Faos.13018","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/aos.13018","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,16]],"date-time":"2023-09-16T20:34:47Z","timestamp":1694896487000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/aos.13018"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,4]]},"references-count":9,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2016,11]]}},"alternative-id":["10.1111\/aos.13018"],"URL":"https:\/\/doi.org\/10.1111\/aos.13018","archive":["Portico"],"relation":{},"ISSN":["1755-375X","1755-3768"],"issn-type":[{"value":"1755-375X","type":"print"},{"value":"1755-3768","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,4]]},"assertion":[{"value":"2015-10-03","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2016-01-22","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2016-04-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}