{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T21:20:35Z","timestamp":1785878435132,"version":"3.56.0"},"reference-count":38,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2016,4,30]],"date-time":"2016-04-30T00:00:00Z","timestamp":1461974400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Ophthalmologica"],"published-print":{"date-parts":[[2016,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>To assess forward light scatter (stray light) before and after intrastromal corneal ring segment (<jats:styled-content style=\"fixed-case\">ICRS<\/jats:styled-content>) implantation at different stages of keratoconus and to examine correlation between postoperative stray light and visual acuity (<jats:styled-content style=\"fixed-case\">VA<\/jats:styled-content>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In 27 eyes of 27 subjects with keratoconus, stray light was determined using the compensation comparison technique before and 6\u00a0months after <jats:styled-content style=\"fixed-case\">ICRS<\/jats:styled-content> implantation. Monocular corrected distance <jats:styled-content style=\"fixed-case\">VA<\/jats:styled-content> (<jats:styled-content style=\"fixed-case\">CDVA<\/jats:styled-content>) was measured using a high\u2010contrast log<jats:styled-content style=\"fixed-case\">MAR<\/jats:styled-content> letter chart. Corneal higher\u2010order aberrations (<jats:styled-content style=\"fixed-case\">HOA<\/jats:styled-content>s), contrast sensitivity (<jats:styled-content style=\"fixed-case\">CS<\/jats:styled-content>) and minimum corneal thickness (<jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content>) were also measured.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Mean <jats:styled-content style=\"fixed-case\">CDVA<\/jats:styled-content> was 0.42\u00a0\u00b1\u00a00.28 preoperatively and 0.24\u00a0\u00b1\u00a00.15 log<jats:styled-content style=\"fixed-case\">MAR<\/jats:styled-content> postoperatively (p\u00a0&lt;\u00a00.01). Mean corneal coma\u2010like aberration decreased postoperatively (<jats:styled-content style=\"fixed-case\">RMS<\/jats:styled-content> 0.55\u00a0\u00b1\u00a01.18\u00a0<jats:italic>\u03bc<\/jats:italic>m, p\u00a0&lt;\u00a00.01). Minimum <jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content> increased 25.31\u00a0\u00b1\u00a018.59\u00a0<jats:italic>\u03bc<\/jats:italic>m (p\u00a0&lt;\u00a00.01). Mean preoperative and postoperative stray light were 1.36\u00a0\u00b1\u00a00.31 and 1.48\u00a0\u00b1\u00a00.32 log units, respectively (p\u00a0&lt;\u00a00.01). Mean changes produced in stray light (worsening) were 0.03\u00a0\u00b1\u00a00.21 (p\u00a0&gt;\u00a00.05) for stage I, 0.13\u00a0\u00b1\u00a00.14 (p\u00a0=\u00a00.013) for stage <jats:styled-content style=\"fixed-case\">II<\/jats:styled-content> and 0.18\u00a0\u00b1\u00a00.21 (p\u00a0=\u00a00.023) for stage <jats:styled-content style=\"fixed-case\">III<\/jats:styled-content>. Significant positive correlation (<jats:italic>r<\/jats:italic>\u00a0=\u00a00.47, p\u00a0=\u00a00.01) was detected between postoperative stray light and postoperative <jats:styled-content style=\"fixed-case\">CDVA<\/jats:styled-content> such that as stray light increased, <jats:styled-content style=\"fixed-case\">CDVA<\/jats:styled-content> worsened (higher log<jats:styled-content style=\"fixed-case\">MAR<\/jats:styled-content> values). Postoperative stray light was neither associated with <jats:styled-content style=\"fixed-case\">HOA<\/jats:styled-content>s, <jats:styled-content style=\"fixed-case\">CS<\/jats:styled-content> nor minimum <jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Stray light values in these patients with keratoconus were higher than normal preoperatively. In eyes with stage <jats:styled-content style=\"fixed-case\">II<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">III<\/jats:styled-content> keratoconus, stray light increased 6\u00a0months after <jats:styled-content style=\"fixed-case\">ICRS<\/jats:styled-content> placement. Higher postoperative stray light was correlated with a worse visual acuity outcome.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aos.13056","type":"journal-article","created":{"date-parts":[[2016,5,1]],"date-time":"2016-05-01T10:48:05Z","timestamp":1462099685000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Forward light scatter and visual acuity before and after intrastromal corneal ring segment implantation at different stages of keratoconus"],"prefix":"10.1111","volume":"94","author":[{"given":"Mar\u00eda Cinta","family":"Puell","sequence":"first","affiliation":[{"name":"Applied Vision Research Group Faculty of Optics and Optometry Complutense University of Madrid Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jes\u00fas","family":"Carballo\u2010\u00c1lvarez","sequence":"additional","affiliation":[{"name":"Applied Vision Research Group Faculty of Optics and Optometry Complutense University of Madrid Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,4,30]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00417-011-1759-9"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2006.06.025"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.visres.2013.05.004"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.84.1.60"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2012.09.025"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clae.2014.06.001"},{"key":"e_1_2_5_8_1","first-page":"121","article-title":"Collagen fibril orientation in the human corneal stroma and its implication in keratoconus","volume":"38","author":"Daxer A","year":"1997","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.05-0690"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/aos.12253"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.3928\/1081597X-20100114-05"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clae.2011.07.001"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2007.04.067"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/aos.12811"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.04-1253"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10384-006-0336-y"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2007.09.002"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2013.08.017"},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1442-9071.2010.02197.x"},{"key":"e_1_2_5_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2009.05.016"},{"key":"e_1_2_5_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2009.07.030"},{"key":"e_1_2_5_22_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.09-5017"},{"key":"e_1_2_5_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0039-6257(97)00119-7"},{"key":"e_1_2_5_24_1","doi-asserted-by":"crossref","first-page":"310","DOI":"10.3928\/1081-597X-20010501-04","article-title":"Epithelial and stromal changes induced by intacs examined by three\u2010dimensional very high\u2010frequency digital ultrasound","volume":"17","author":"Reinstein DZ","year":"2001","journal-title":"J Refract Surg"},{"key":"e_1_2_5_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0886-3350(00)00575-7"},{"key":"e_1_2_5_26_1","doi-asserted-by":"publisher","DOI":"10.3109\/08820538.2012.730096"},{"key":"e_1_2_5_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2006.08.059"},{"key":"e_1_2_5_28_1","first-page":"1846","article-title":"Proteoglycan molecules in keratoconus corneas","volume":"32","author":"Sawaguchi S","year":"1991","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"e_1_2_5_29_1","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.116.1.62"},{"key":"e_1_2_5_30_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.10-5375"},{"key":"e_1_2_5_31_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1442-9071.2004.00805.x"},{"key":"e_1_2_5_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2009.05.036"},{"key":"e_1_2_5_33_1","doi-asserted-by":"publisher","DOI":"10.1097\/00003226-200303000-00014"},{"key":"e_1_2_5_34_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006324-199502000-00003"},{"key":"e_1_2_5_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2007.05.037"},{"key":"e_1_2_5_36_1","doi-asserted-by":"publisher","DOI":"10.1097\/ICO.0b013e31823f8ab7"},{"key":"e_1_2_5_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2012.08.020"},{"key":"e_1_2_5_38_1","doi-asserted-by":"publisher","DOI":"10.1117\/1.JBO.17.11.116010"},{"key":"e_1_2_5_39_1","doi-asserted-by":"publisher","DOI":"10.1097\/00003226-200011000-00009"}],"container-title":["Acta Ophthalmologica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Faos.13056","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Faos.13056","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/aos.13056","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,24]],"date-time":"2023-09-24T16:48:21Z","timestamp":1695574101000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/aos.13056"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,4,30]]},"references-count":38,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2016,12]]}},"alternative-id":["10.1111\/aos.13056"],"URL":"https:\/\/doi.org\/10.1111\/aos.13056","archive":["Portico"],"relation":{},"ISSN":["1755-375X","1755-3768"],"issn-type":[{"value":"1755-375X","type":"print"},{"value":"1755-3768","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,4,30]]},"assertion":[{"value":"2015-11-18","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2016-02-15","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2016-04-30","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}