{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T13:14:24Z","timestamp":1791810864455,"version":"4.3.4"},"reference-count":17,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2016,5,23]],"date-time":"2016-05-23T00:00:00Z","timestamp":1463961600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100004336","name":"Novartis","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004336","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Ophthalmologica"],"published-print":{"date-parts":[[2016,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>To identify predictors of intraocular pressure (<jats:styled-content style=\"fixed-case\">IOP<\/jats:styled-content>) reduction following selective laser trabeculoplasty (<jats:styled-content style=\"fixed-case\">SLT<\/jats:styled-content>) in patients with high\u2010 and low\u2010pressure primary open\u2010angle glaucoma, who are already taking maximally tolerated <jats:styled-content style=\"fixed-case\">IOP<\/jats:styled-content>\u2010lowering medication and need further <jats:styled-content style=\"fixed-case\">IOP<\/jats:styled-content> reduction.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In this prospective interventional case series, 157 eyes of 157 open\u2010angle glaucoma patients who were assigned for <jats:styled-content style=\"fixed-case\">SLT<\/jats:styled-content> for further <jats:styled-content style=\"fixed-case\">IOP<\/jats:styled-content> reduction were included. Each patient had diurnal <jats:styled-content style=\"fixed-case\">IOP<\/jats:styled-content> measurements taken before and on average 6\u00a0months following <jats:styled-content style=\"fixed-case\">SLT<\/jats:styled-content>. The mean of six <jats:styled-content style=\"fixed-case\">IOP<\/jats:styled-content> measurements was compared. The following parameters were analysed for their association with <jats:styled-content style=\"fixed-case\">SLT<\/jats:styled-content> success: age, gender, spherical equivalent, high\u2010pressure or normal\u2010pressure open\u2010angle glaucoma, number and type of pressure\u2010lowering medications, lens status, pre\u2010<jats:styled-content style=\"fixed-case\">SLT IOP<\/jats:styled-content>,<jats:styled-content style=\"fixed-case\"> IOP<\/jats:styled-content> at the time of diagnosis, duration of glaucoma, visual field stage and central corneal thickness.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The only parameter that was predictive for absolute and relative mean diurnal <jats:styled-content style=\"fixed-case\">IOP<\/jats:styled-content> reduction after <jats:styled-content style=\"fixed-case\">SLT<\/jats:styled-content> was the preoperative mean diurnal <jats:styled-content style=\"fixed-case\">IOP<\/jats:styled-content>. One hundred per cent of the patients with a mean diurnal preoperative <jats:styled-content style=\"fixed-case\">IOP<\/jats:styled-content> of more than 18\u00a0mmHg had an <jats:styled-content style=\"fixed-case\">IOP<\/jats:styled-content> reduction after <jats:styled-content style=\"fixed-case\">SLT<\/jats:styled-content>. With mean diurnal preoperative values of 14\u201318\u00a0mmHg, 83.1% of the patients, and with values below 14\u00a0mmHg only 64% of the patients, showed an <jats:styled-content style=\"fixed-case\">IOP<\/jats:styled-content> reduction. This difference was statistically significant (&gt;18 compared to 14\u201318: p\u00a0=\u00a00.002; &gt;18 compared to &lt;14: p\u00a0=\u00a00.001; 14\u201318 compared to &lt;14: p\u00a0=\u00a00.030).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The pressure\u2010lowering effect of <jats:styled-content style=\"fixed-case\">SLT<\/jats:styled-content> can best be predicted by the individual <jats:styled-content style=\"fixed-case\">IOP<\/jats:styled-content> level before treatment. Patients with mean diurnal <jats:styled-content style=\"fixed-case\">IOP<\/jats:styled-content> levels below 14\u00a0mmHg might not benefit from the procedure at all.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aos.13094","type":"journal-article","created":{"date-parts":[[2016,5,24]],"date-time":"2016-05-24T10:24:15Z","timestamp":1464085455000},"page":"692-696","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":52,"title":["Preoperative intraocular pressure as a predictor of selective laser trabeculoplasty efficacy"],"prefix":"10.1111","volume":"94","author":[{"given":"Karin R.","family":"Pillunat","sequence":"first","affiliation":[{"name":"Department of Ophthalmology Medical Faculty Carl Gustav Carus Technische Universit\u00e4t Dresden Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eberhard","family":"Spoerl","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology Medical Faculty Carl Gustav Carus Technische Universit\u00e4t Dresden Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Greta","family":"Elfes","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology Medical Faculty Carl Gustav Carus Technische Universit\u00e4t Dresden Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lutz E.","family":"Pillunat","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology Medical Faculty Carl Gustav Carus Technische Universit\u00e4t Dresden Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,5,23]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00417-013-2522-1"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/642869"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2011.04.036"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00347-012-2593-0"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.2004.062414"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000000236"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/IJG.0000000000000089"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2007.03.016"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/IJG.0b013e31815f52cb"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/IJG.0b013e3181e3d2c1"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/00061198-200604000-00009"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1089\/jop.2007.0027"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/ICO.0b013e318243f684"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1038\/eye.2009.1"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/00055735-199404000-00010"},{"key":"e_1_2_5_17_1","doi-asserted-by":"crossref","first-page":"182","DOI":"10.3928\/15428877-20070501-01","article-title":"Selective laser trabeculoplasty in phakic and pseudophakic eyes","volume":"38","author":"Werner M","year":"2007","journal-title":"Ophthalmic Surg Lasers Imaging"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/ceo.12452"}],"container-title":["Acta Ophthalmologica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Faos.13094","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/aos.13094","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,16]],"date-time":"2023-09-16T20:34:03Z","timestamp":1694896443000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/aos.13094"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,5,23]]},"references-count":17,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2016,11]]}},"alternative-id":["10.1111\/aos.13094"],"URL":"https:\/\/doi.org\/10.1111\/aos.13094","archive":["Portico"],"relation":{},"ISSN":["1755-375X","1755-3768"],"issn-type":[{"value":"1755-375X","type":"print"},{"value":"1755-3768","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,5,23]]},"assertion":[{"value":"2015-12-23","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2016-03-17","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2016-05-23","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}