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We reviewed the literature to better understand the safety and efficacy of the adjunctive role of anti\u2010<jats:styled-content style=\"fixed-case\">VEGF<\/jats:styled-content> treatments for pterygium excision. Without surgery, anti\u2010<jats:styled-content style=\"fixed-case\">VEGF<\/jats:styled-content> alone may favourably alter symptoms and vascularity, but does not cause pterygium regression. Some evidence supports the use of anti\u2010<jats:styled-content style=\"fixed-case\">VEGF<\/jats:styled-content> as an adjuvant therapy to surgery, especially when using a higher dose and a more frequent dosing regimen. Overall, anti\u2010<jats:styled-content style=\"fixed-case\">VEGF<\/jats:styled-content> is generally safe and well tolerated in patients with pterygium. Currently, the evidence does not conclusively support the use of anti\u2010<jats:styled-content style=\"fixed-case\">VEGF<\/jats:styled-content> in pterygium surgery. However, further research may guide unanswered questions regarding the interaction between <jats:styled-content style=\"fixed-case\">VEGF<\/jats:styled-content> and other factors responsible for pterygium growth. In addition, the optimal route and dosage of anti\u2010<jats:styled-content style=\"fixed-case\">VEGF<\/jats:styled-content> administration is not yet known.<\/jats:p>","DOI":"10.1111\/aos.13178","type":"journal-article","created":{"date-parts":[[2017,1,19]],"date-time":"2017-01-19T18:57:45Z","timestamp":1484852265000},"page":"20-27","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["Use of anti\u2010vascular endothelial growth factor in the management of pterygium"],"prefix":"10.1111","volume":"95","author":[{"given":"Renata Kiri","family":"Mak","sequence":"first","affiliation":[{"name":"Hospital Authority Hong Kong Hong Kong"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tommy Chung Yan","family":"Chan","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology LKS Faculty of Medicine The University of Hong Kong Pokfulam Hong Kong"},{"name":"Hong Kong Eye Hospital Kowloon Hong 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