{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,9,22]],"date-time":"2023-09-22T21:28:33Z","timestamp":1695418113809},"reference-count":34,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2016,8,6]],"date-time":"2016-08-06T00:00:00Z","timestamp":1470441600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Ophthalmologica"],"published-print":{"date-parts":[[2016,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>To compare objective refraction using small\u2010zone eccentric laser ray tracing (LRT) wavefront aberrometry to standard autorefraction in keratoconus (<jats:styled-content style=\"fixed-case\">KC<\/jats:styled-content>), and whether the visual acuities achieved with these refractions differ from corresponding values in healthy eyes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Twenty\u2010nine eyes of 29 patients with <jats:styled-content style=\"fixed-case\">KC<\/jats:styled-content> and 29 eyes of 29 healthy controls were included in this prospective unmasked case\u2013control study. The uncorrected (<jats:styled-content style=\"fixed-case\">UCVA<\/jats:styled-content>) and spectacle\u2010corrected (<jats:styled-content style=\"fixed-case\">SCVA<\/jats:styled-content>) Early Treatment Diabetic Retinopathy Study (<jats:styled-content style=\"fixed-case\">ETDRS<\/jats:styled-content>) visual acuities based on refractions derived from <jats:styled-content style=\"fixed-case\">LRT<\/jats:styled-content> in central and four eccentric zones were compared to those achieved with standard autorefraction. The spherical equivalent (<jats:italic>M<\/jats:italic>) and two astigmatic power vectors (C0 and C45) were calculated for all refractions. Pentacam <jats:styled-content style=\"fixed-case\">HR<\/jats:styled-content><jats:sup>\u00ae<\/jats:sup> was used to generate keratometry readings of the corresponding zones.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In <jats:styled-content style=\"fixed-case\">KC<\/jats:styled-content>, the refraction from the upper nasal zone rendered a higher <jats:styled-content style=\"fixed-case\">SCVA<\/jats:styled-content> than the standard autorefraction more often than in the controls (p\u00a0&lt;\u00a00.001). There were no significant variation in <jats:italic>M<\/jats:italic> between the different <jats:styled-content style=\"fixed-case\">LRT<\/jats:styled-content> measurement points in the control group, but central data provided the best <jats:styled-content style=\"fixed-case\">SCVA<\/jats:styled-content>. The <jats:styled-content style=\"fixed-case\">UCVA<\/jats:styled-content>:s and <jats:styled-content style=\"fixed-case\">SCVA<\/jats:styled-content>:s were worse in <jats:styled-content style=\"fixed-case\">KC<\/jats:styled-content>, and the <jats:styled-content style=\"fixed-case\">KC<\/jats:styled-content> eyes showed inferior myopia and superior hyperopia. Multiple refractions rendered similar <jats:styled-content style=\"fixed-case\">SCVA<\/jats:styled-content>:s in <jats:styled-content style=\"fixed-case\">KC<\/jats:styled-content>. Pentacam <jats:styled-content style=\"fixed-case\">HR<\/jats:styled-content><jats:sup>\u00ae<\/jats:sup> showed higher keratometry readings infero\u2010temporally, but also lower readings supero\u2010nasally, compared to controls.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>In <jats:styled-content style=\"fixed-case\">KC<\/jats:styled-content>, eccentric <jats:styled-content style=\"fixed-case\">LRT<\/jats:styled-content> measurements gave better <jats:styled-content style=\"fixed-case\">SCVA<\/jats:styled-content> than standard autorefraction more often than in healthy eyes. Eccentric <jats:styled-content style=\"fixed-case\">LRT<\/jats:styled-content> may become a valuable tool in the demanding task of subjective refraction in <jats:styled-content style=\"fixed-case\">KC<\/jats:styled-content>.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aos.13183","type":"journal-article","created":{"date-parts":[[2016,8,6]],"date-time":"2016-08-06T12:11:23Z","timestamp":1470485483000},"page":"679-684","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Eccentric small\u2010zone ray tracing wavefront aberrometry for refraction in keratoconus"],"prefix":"10.1111","volume":"94","author":[{"given":"Anneli","family":"Fredriksson","sequence":"first","affiliation":[{"name":"Department of Clinical Sciences\/Ophthalmology Ume\u00e5 University Hospital Ume\u00e5 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