{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T23:05:38Z","timestamp":1791241538359,"version":"4.1.0"},"reference-count":33,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2016,8,18]],"date-time":"2016-08-18T00:00:00Z","timestamp":1471478400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Ophthalmologica"],"published-print":{"date-parts":[[2017,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>To report the feasibility and long\u2010term safety of lensectomy and iris\u2010claw intraocular lens (<jats:styled-content style=\"fixed-case\">IOL<\/jats:styled-content>) implantation to treat children with severe ectopia lentis in a paediatric tertiary hospital.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Prospective cohort study of 21 eyes from 12 patients with severe ectopia lentis and visual acuity &lt;20\/63. All eyes underwent 23\u2010gauge pars plana vitrectomy, lensectomy, iridectomy and Artisan <jats:styled-content style=\"fixed-case\">IOL<\/jats:styled-content> implantation in the anterior chamber with iris\u2010claw enclavation via pars plana. Mean age at surgery was 8.0\u00a0\u00b1\u00a05.3\u00a0yo (range 3\u201317\u00a0years). A full ophthalmologic examination including best\u2010corrected visual acuity (<jats:styled-content style=\"fixed-case\">BCVA<\/jats:styled-content>), biomicroscopy, intraocular pressure (<jats:styled-content style=\"fixed-case\">IOP<\/jats:styled-content>) measurement, fundus evaluation and central endothelial cell count (<jats:styled-content style=\"fixed-case\">cECC<\/jats:styled-content>) was performed pretreatment, at 3\u00a0months' postsurgery, and every 6\u00a0months thereafter. Ultrasound biomicroscopy (<jats:styled-content style=\"fixed-case\">UBM<\/jats:styled-content>) was performed 12\u00a0months after surgery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Mean follow\u2010up was 39.3\u00a0\u00b1\u00a013.0\u00a0months. Best\u2010corrected visual acuity (BCVA) (mean\u00a0\u00b1\u00a0<jats:styled-content style=\"fixed-case\">SD<\/jats:styled-content>) improved from 0.91\u00a0\u00b1\u00a00.29 logMar preoperatively to 0.18\u00a0\u00b1\u00a00.23 logMar at final follow\u2010up (p\u00a0&lt;\u00a00.0001). Mean distance from the endothelium to the anterior <jats:styled-content style=\"fixed-case\">IOL<\/jats:styled-content> surface after surgery was 3.11\u00a0\u00b1\u00a00.61\u00a0mm. Postsurgically, <jats:styled-content style=\"fixed-case\">cECC<\/jats:styled-content> loss was 5.04%\u00a0\u00b1\u00a09.58% with an annual <jats:styled-content style=\"fixed-case\">cECC<\/jats:styled-content> loss rate of 3.16%\u00a0\u00b1\u00a04.46%. One patient developed <jats:styled-content style=\"fixed-case\">IOL<\/jats:styled-content> dislocation and retinal detachment after severe ocular contusion requiring vitrectomy, <jats:styled-content style=\"fixed-case\">IOL<\/jats:styled-content> refixation and gas tamponade. Another patient developed cystoid macular oedema, managed with intravitreal dexamethasone.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This technique is both feasible and effective to manage severe ectopia lentis in children. Lifetime ophthalmic follow\u2010up including <jats:styled-content style=\"fixed-case\">cECC<\/jats:styled-content> measurement, <jats:styled-content style=\"fixed-case\">IOL<\/jats:styled-content> position monitoring and fundus examination is mandatory in these patients.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aos.13192","type":"journal-article","created":{"date-parts":[[2016,8,18]],"date-time":"2016-08-18T11:06:43Z","timestamp":1471518403000},"page":"170-174","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":31,"title":["Anterior iris\u2010claw intraocular lens implantation for the management of nontraumatic ectopia lentis: long\u2010term outcomes in a paediatric cohort"],"prefix":"10.1111","volume":"95","author":[{"given":"Jaume","family":"Catal\u00e0\u2010Mora","sequence":"first","affiliation":[{"name":"Hospital Sant Joan de D\u00e9u Esplugues de Llobregat Barcelona Spain"},{"name":"Ophthalmological Institute del Pilar Barcelona Spain"},{"name":"Surgery Department Universitat Aut\u00f2noma Barcelona Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Cuadras","sequence":"additional","affiliation":[{"name":"Advisory Service and Statistical Methodology Research Fundaci\u00f3 Sant Joan de D\u00e9u Esplugues de Llobregat Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jes\u00fas","family":"D\u00edaz\u2010Cascajosa","sequence":"additional","affiliation":[{"name":"Hospital Sant Joan de D\u00e9u Esplugues de Llobregat Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marta","family":"Castany\u2010Aregall","sequence":"additional","affiliation":[{"name":"Hospital Vall d'Hebron Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joan","family":"Prat\u2010Bartomeu","sequence":"additional","affiliation":[{"name":"Hospital Sant Joan de D\u00e9u Esplugues de Llobregat Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9","family":"Garc\u00eda\u2010Arum\u00ed","sequence":"additional","affiliation":[{"name":"Surgery Department Universitat Aut\u00f2noma Barcelona Barcelona Spain"},{"name":"Hospital Vall d'Hebron Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,8,18]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.5301\/ejo.5000527"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2007.05.014"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2006.08.025"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0886-3350(98)80168-5"},{"key":"e_1_2_6_6_1","first-page":"375","article-title":"[Is the decrease in corneal endothelial cell density in relation to age linear?]","volume":"232","author":"Beuschel R","year":"2015","journal-title":"Klin Monbl Augenheilkd"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2008.08.033"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/IAE.0b013e31824d4f06"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/aos.12175"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjophthalmol-2011-300579"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2011.03.051"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/ICU.0b013e3282f29f01"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.survophthal.2007.06.010"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjophthalmol-2013-304144"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.2147\/OPTH.S56484"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12886-015-0146-4"},{"key":"e_1_2_6_17_1","first-page":"784","article-title":"[Endothelial cell loss after retropupillary iris\u2010claw intraocular lens implantation]","volume":"231","author":"Gonnermann J","year":"2014","journal-title":"Klin Monbl Augenheilkd"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2007.04.026"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2014.08.002"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2007.01.032"},{"key":"e_1_2_6_21_1","first-page":"333","article-title":"A comparative study of human corneal keratocyte and endothelial cell density during aging","volume":"16","author":"M\u00f8ller\u2010Pedersen T","year":"1997","journal-title":"Cornea"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2007.04.009"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaapos.2006.08.017"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.1990.01070040099039"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1097\/ICU.0b013e32835622f8"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.3928\/01913913-20130604-01"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.3109\/08820538.2013.825276"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.3928\/01913913-20130108-02"},{"key":"e_1_2_6_29_1","doi-asserted-by":"publisher","DOI":"10.3928\/01913913-20150714-02"},{"key":"e_1_2_6_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaapos.2007.06.015"},{"key":"e_1_2_6_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2010.07.040"},{"key":"e_1_2_6_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2013.07.014"},{"key":"e_1_2_6_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2012.02.018"},{"key":"e_1_2_6_34_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1442-9071.2011.02612.x"}],"container-title":["Acta Ophthalmologica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Faos.13192","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Faos.13192","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/aos.13192","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,24]],"date-time":"2023-09-24T07:40:00Z","timestamp":1695541200000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/aos.13192"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,8,18]]},"references-count":33,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2017,3]]}},"alternative-id":["10.1111\/aos.13192"],"URL":"https:\/\/doi.org\/10.1111\/aos.13192","archive":["Portico"],"relation":{},"ISSN":["1755-375X","1755-3768"],"issn-type":[{"value":"1755-375X","type":"print"},{"value":"1755-3768","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,8,18]]},"assertion":[{"value":"2016-04-10","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2016-06-13","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2016-08-18","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}