{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,16]],"date-time":"2023-10-16T20:56:21Z","timestamp":1697489781373},"reference-count":38,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2016,12,14]],"date-time":"2016-12-14T00:00:00Z","timestamp":1481673600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100004348","name":"Stockholms L\u00e4ns Landsting","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004348","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010305","name":"Bernadotte Foundation For Children\u2019s Eyecare","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100010305","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Ophthalmologica"],"published-print":{"date-parts":[[2017,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>To evaluate ophthalmological abnormalities in children with acute encephalitis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Thirty\u2010six children included in a hospital\u2010based prospectively and consecutively collected cohort of children with acute encephalitis were investigated for ophthalmological abnormalities. The investigation included clinical ophthalmological examination, fundus photography, neuro\u2010ophthalmological examinations as well as visual and stereo acuity. Results on laboratory examinations, clinical findings, neuroimaging and electroencephalography registrations were recorded for all children.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The median age was 4.0\u00a0years (Interquartile Range 1.9\u20139.8). The aetiology was identified in 74% of cases. Three of 36 patients were found to have abnormal ophthalmological findings related to the encephalitis. Transient sixth nerve palsy was seen in a 15\u2010year\u2010old child and transient visual impairment was seen in a 3.5\u2010year\u2010old child. Bilateral miosis and ptosis, i.e. autonomic nerve system symptoms, were seen in an 11\u2010month\u2010old child, with herpes simplex 1 and <jats:italic>N<\/jats:italic>\u2010methyl\u2010<jats:sc>d<\/jats:sc>\u2010aspartate receptor antibody encephalitis. All three children recovered and improved their ophthalmological function with time.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Only 3 of 36 children were found to have ophthalmological abnormalities due to encephalitis and they all improved with time. Thus, ophthalmological consultation does not seem to fit in a screening programme for childhood encephalitis but should be considered in selected cases.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aos.13305","type":"journal-article","created":{"date-parts":[[2016,12,15]],"date-time":"2016-12-15T09:59:04Z","timestamp":1481795944000},"page":"66-73","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Ophthalmological findings in children with encephalitis"],"prefix":"10.1111","volume":"95","author":[{"given":"Kerstin","family":"Hellgren","sequence":"first","affiliation":[{"name":"Department of Neuropediatrics Astrid Lindgren Children's Hospital Karolinska University Hospital Stockholm Sweden"},{"name":"Department of Clinical Neuroscience Karolinska Institutet Stockholm 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