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All 40 eyes received standard phacoemulsification and intraocular lens implantation. The mean retinal arterial and venular oxygen saturation (SO<jats:sub>2<\/jats:sub>) levels were measured using the Oxymap system prior to, immediately after and 3\u00a0months after cataract surgery. The arterial\u2013venular difference (AVD) was calculated as the difference between the arterial and venular saturations. Linear regression analysis was performed to identify the relationship between the lens density grades and changes in the measured retina vessel SO<jats:sub>2<\/jats:sub>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The mean age of the subjects was 64.1\u00a0\u00b1\u00a07.8\u00a0years, and 14 (35%) were male. The mean SO<jats:sub>2<\/jats:sub> level increased in the retinal arterioles from 90.5\u00a0\u00b1\u00a07.8% to 95.0\u00a0\u00b1\u00a06.7% immediately postoperatively and to 98.3\u00a0\u00b1\u00a05.3% at 3\u00a0months after surgery (p\u00a0&lt;\u00a00.001). The mean venular saturation levels were 43.4\u00a0\u00b1\u00a09.7%, 58.0\u00a0\u00b1\u00a08.5% and 61.9\u00a0\u00b1\u00a06.5% at baseline, immediately after and at 3\u00a0months postoperatively, respectively, with a statistically significant increase after surgery (p\u00a0&lt;\u00a00.001). The mean AVD significantly decreased from 47.1\u00a0\u00b1\u00a08.9% before surgery to 37.1\u00a0\u00b1\u00a07.3% immediately after and 36.4\u00a0\u00b1\u00a06.4% 3\u00a0months after surgery (p\u00a0&lt;\u00a00.02). A linear regression model indicated that denser lens opacity was significantly associated with a larger amplitude of the venular SO<jats:sub>2<\/jats:sub> level and the AVD after cataract surgery: change of venous SO<jats:sub>2<\/jats:sub>\u00a0=\u00a05.934\u20130.191\u00a0\u00d7\u00a0Age\u00a0+\u00a013.534\u00a0\u00d7\u00a0Lens Grade (age: p\u00a0=\u00a00.586; lens grade: p\u00a0&lt;\u00a00.001); change in AVD\u00a0=\u00a0\u22127.438\u20130.037\u00a0\u00d7\u00a0Age\u00a0+\u00a07.744\u00a0\u00d7\u00a0Lens Grade (age: p\u00a0=\u00a00.917; lens grade: p\u00a0=\u00a00.031).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Retinal arterial and venular oxygen saturation levels are significantly increased after cataract surgery, and increase rates vary with the preoperative grading of lens density.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aos.13332","type":"journal-article","created":{"date-parts":[[2016,11,19]],"date-time":"2016-11-19T07:32:58Z","timestamp":1479540778000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Preoperative and postoperative measurements of retinal vessel oxygen saturation in patients with different grades of cataracts"],"prefix":"10.1111","volume":"95","author":[{"given":"Hui","family":"Chen","sequence":"first","affiliation":[{"name":"State Key Laboratory of Ophthalmology Zhongshan Ophthalmic Center Sun Yat\u2010sen University Guangzhou Guangdong China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haotian","family":"Lin","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Ophthalmology Zhongshan Ophthalmic Center Sun Yat\u2010sen University Guangzhou Guangdong 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