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We assessed the 2\u2010years clinical outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Logarithm of the minimal angle of resolution (Log<jats:styled-content style=\"fixed-case\">MAR<\/jats:styled-content>)\u2010corrected distance visual acuity (CDVA) was \u22120.23\u00a0\u00b1\u00a00.07 in the <jats:styled-content style=\"fixed-case\">SMILE<\/jats:styled-content> group and \u22120.24\u00a0\u00b1\u00a00.07 in the wavefront\u2010guided <jats:styled-content style=\"fixed-case\">LASIK<\/jats:styled-content> group 2\u00a0years postoperatively (p<jats:italic>\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.82). Logarithm of the minimal angle of resolution\u2010uncorrected distance visual acuity (UDVA) was \u22120.18\u00a0\u00b1\u00a00.09 and \u22120.15\u00a0\u00b1\u00a00.11 (p<jats:italic>\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.30, respectively). In the <jats:styled-content style=\"fixed-case\">SMILE<\/jats:styled-content> and wavefront\u2010guided <jats:styled-content style=\"fixed-case\">LASIK<\/jats:styled-content> groups 2\u00a0years postoperatively, 100% and 73% of eyes, respectively, were within 0.5\u00a0D of the prompted <jats:styled-content style=\"fixed-case\">MRSE<\/jats:styled-content> correction (p<jats:italic>\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.005). Changes in the <jats:styled-content style=\"fixed-case\">MRSE<\/jats:styled-content> of \u22120.10\u00a0\u00b1\u00a00.30\u00a0D and \u22120.23\u00a0\u00b1\u00a00.51\u00a0D occurred from 3\u00a0months to 2\u00a0years (p<jats:italic>\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.40, respectively). We found a significant correlation between myopic regression and the changes in the keratometric readings from 3\u00a0months to 2\u00a0years after wavefront\u2010guided <jats:styled-content style=\"fixed-case\">LASIK<\/jats:styled-content> (<jats:italic>r<\/jats:italic>\u00a0=\u00a0\u22120.48, p<jats:italic>\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.002), but not after <jats:styled-content style=\"fixed-case\">SMILE<\/jats:styled-content> (<jats:italic>r<\/jats:italic>\u00a0=\u00a0\u22120.004, p<jats:italic>\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.90).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Small\u2010incision lenticule extraction offers better refractive outcomes than wavefront\u2010guided <jats:styled-content style=\"fixed-case\">LASIK<\/jats:styled-content> during a 2\u2010years follow\u2010up for the correction of myopia and myopic astigmatism.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aos.13470","type":"journal-article","created":{"date-parts":[[2017,6,20]],"date-time":"2017-06-20T07:30:58Z","timestamp":1497943858000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":40,"title":["Two\u2010years results of small\u2010incision lenticule extraction and wavefront\u2010guided laser <i>in\u00a0situ<\/i> keratomileusis for Myopia"],"prefix":"10.1111","volume":"96","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0767-4214","authenticated-orcid":false,"given":"Hidenaga","family":"Kobashi","sequence":"first","affiliation":[{"name":"Department of Ophthalmology University of Kitasato School of Medicine Kanagawa Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazutaka","family":"Kamiya","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology University of Kitasato School of Medicine Kanagawa 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