{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T10:22:33Z","timestamp":1787739753480,"version":"build-2784847793"},"reference-count":43,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2017,6,21]],"date-time":"2017-06-21T00:00:00Z","timestamp":1498003200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Ophthalmologica"],"published-print":{"date-parts":[[2017,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:label\/><jats:p>Bilateral diffuse uveal melanocytic proliferation (<jats:styled-content style=\"fixed-case\">BDUMP<\/jats:styled-content>) is a rare paraneoplastic intraocular disease that causes progressive visual loss in patients driven by an IgG factor associated with an underlying malignancy. Characteristic ocular findings include exudative retinal detachment, rapid cataract formation and uveal melanocytic tumours. The awareness and documentation of <jats:styled-content style=\"fixed-case\">BDUMP<\/jats:styled-content> has increased during the past decade, and the increasing amount of data collected demonstrates the effect of treatment with plasmapheresis and the value of diagnostic tools in <jats:styled-content style=\"fixed-case\">BDUMP<\/jats:styled-content> such as genetic and immunologic investigations. The literature of <jats:styled-content style=\"fixed-case\">BDUMP<\/jats:styled-content> has not been reviewed since 2003, and there is a growing need for an updated review on diagnosis and management of <jats:styled-content style=\"fixed-case\">BDUMP<\/jats:styled-content>. We review the literature and report a case of <jats:styled-content style=\"fixed-case\">BDUMP<\/jats:styled-content> with a white ciliary body tumour, iris rubeosis, increased iris pigmentation and cataract.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aos.13481","type":"journal-article","created":{"date-parts":[[2017,6,21]],"date-time":"2017-06-21T09:38:40Z","timestamp":1498037920000},"page":"439-445","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":69,"title":["Bilateral diffuse uveal melanocytic proliferation: Case report and literature review"],"prefix":"10.1111","volume":"95","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9849-0057","authenticated-orcid":false,"given":"Kristian","family":"Klemp","sequence":"first","affiliation":[{"name":"Department of Ophthalmology Rigshospitalet University of Copenhagen Copenhagen 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