{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T00:44:23Z","timestamp":1787013863564,"version":"build-2736575974"},"reference-count":21,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2017,6,29]],"date-time":"2017-06-29T00:00:00Z","timestamp":1498694400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Ophthalmologica"],"published-print":{"date-parts":[[2018,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>Craniopharyngioma often causes visual loss due to the close relation to the anterior visual pathways. This study investigates the incidence and predictors of visual outcomes in patients with craniopharyngioma.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Data from sixty\u2010six patients who underwent surgery for craniopharyngioma from 2009 to 2013 in Denmark were reviewed. Primary outcomes were visual acuity (\n                      <jats:styled-content style=\"fixed-case\">VA<\/jats:styled-content>\n                      ) and visual field (\n                      <jats:styled-content style=\"fixed-case\">VF<\/jats:styled-content>\n                      ) defects from pre\u2010and postoperative visits. Secondary outcomes were optic nerve atrophy (\n                      <jats:styled-content style=\"fixed-case\">OA<\/jats:styled-content>\n                      ) and papilledema.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Fifty\u2010eight patients were included. The\n                      <jats:styled-content style=\"fixed-case\">VA<\/jats:styled-content>\n                      of the patients 1\u2010year after surgery improved by \u22120.16 log(\n                      <jats:styled-content style=\"fixed-case\">MAR<\/jats:styled-content>\n                      ) (95%\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      : \u22120.30 to \u22120.02; p\u00a0=\u00a00.0266). Visual field (VF) defects worsened in 17 eyes (30%), remained stable in 21 eyes (37%) and improved in 19 eyes (33%). The presence of papilledema and the absence of\n                      <jats:styled-content style=\"fixed-case\">OA<\/jats:styled-content>\n                      were significantly correlated with an improvement in\n                      <jats:styled-content style=\"fixed-case\">VA<\/jats:styled-content>\n                      postoperatively (p\u00a0=\u00a00.011 and p\u00a0=\u00a00.011, respectively). Patients undergoing surgery within a week or less after their first ophthalmological examination had a significant improvement in\n                      <jats:styled-content style=\"fixed-case\">VA<\/jats:styled-content>\n                      (\u22120.36; 95%\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      : \u22120.62 to \u22120.09; p\u00a0=\u00a00.0099). Patients undergoing surgery using a subfrontal approach also showed improvement in\n                      <jats:styled-content style=\"fixed-case\">VA<\/jats:styled-content>\n                      (p\u00a0=\u00a00.048). Tumour recurrence had a significantly worse\n                      <jats:styled-content style=\"fixed-case\">VA<\/jats:styled-content>\n                      outcome (p\u00a0=\u00a00.0074).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      Patients show a slight improvement in\n                      <jats:styled-content style=\"fixed-case\">VA<\/jats:styled-content>\n                      1\u2010year after operation for craniopharyngioma. The presence of papilledema and early surgical intervention is associated with a significant improvement in\n                      <jats:styled-content style=\"fixed-case\">VA<\/jats:styled-content>\n                      . Early involvement of a dedicated ophthalmologist is recommended to secure an early detection of a visual decline and potential tumour recurrence.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/aos.13483","type":"journal-article","created":{"date-parts":[[2017,6,29]],"date-time":"2017-06-29T08:36:41Z","timestamp":1498725401000},"page":"39-45","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["Predictors of visual outcome in patients operated for craniopharyngioma \u2013 a Danish national study"],"prefix":"10.1111","volume":"96","author":[{"given":"Mads Forslund","family":"Jacobsen","sequence":"first","affiliation":[{"name":"Department of Ophthalmology Rigshospitalet Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4249-581X","authenticated-orcid":false,"given":"Ann Sofia 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