{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T23:01:46Z","timestamp":1791932506108,"version":"4.3.4"},"reference-count":38,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2017,9,18]],"date-time":"2017-09-18T00:00:00Z","timestamp":1505692800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Ophthalmologica"],"published-print":{"date-parts":[[2018,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>To evaluate long\u2010term outcomes on efficacy and safety of severe uveitic glaucoma treated with a Baerveldt glaucoma implant (<jats:styled-content style=\"fixed-case\">BGI<\/jats:styled-content>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A retrospective study of 47 eyes of 47 patients with uveitic glaucoma treated by a <jats:styled-content style=\"fixed-case\">BGI<\/jats:styled-content> between September 2002 and September 2015. Main outcome measures were intraocular pressure (<jats:styled-content style=\"fixed-case\">IOP<\/jats:styled-content>), number of glaucoma medications, course of the uveitis, visual acuity (<jats:styled-content style=\"fixed-case\">VA<\/jats:styled-content>) and complications.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Mean <jats:styled-content style=\"fixed-case\">IOP<\/jats:styled-content> dropped from 30.6\u00a0\u00b1\u00a08.1\u00a0mmHg with 3.6\u00a0\u00b1\u00a01.1 glaucoma medications at baseline to 10.6\u00a0\u00b1\u00a04.3\u00a0mmHg with 1.0\u00a0\u00b1\u00a01.3 glaucoma medications after a mean follow\u2010up of 63.6\u00a0\u00b1\u00a043.1\u00a0months. In the majority of cases, <jats:styled-content style=\"fixed-case\">IOP<\/jats:styled-content> remained stable during follow\u2010up. However, especially in several patients with viral uveitis, episodes with <jats:styled-content style=\"fixed-case\">IOP<\/jats:styled-content> peaks were observed during a flare\u2010up despite a functioning implant. These peaks remained below preoperative levels. During follow\u2010up, 16 patients (34%) experienced a clinically significant <jats:styled-content style=\"fixed-case\">VA<\/jats:styled-content> loss, mainly because of late\u2010stage glaucoma or hypotony maculopathy. Early postoperative complications were transient choroidal effusion (<jats:italic>n\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>5), shallow\/flat anterior chamber (<jats:italic>n\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>4), hyphaema (<jats:italic>n\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>2) and suprachoroidal haemorrhage (<jats:italic>n\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>1). The most important late postoperative complication was hypotony maculopathy (<jats:italic>n\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>5), three of these in juvenile idiopathic arthritis (<jats:styled-content style=\"fixed-case\">JIA<\/jats:styled-content>) patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The <jats:styled-content style=\"fixed-case\">BGI<\/jats:styled-content> is an effective and safe treatment for patients with refractive secondary glaucoma due to uveitis. In a majority of patients, <jats:styled-content style=\"fixed-case\">VA<\/jats:styled-content> remains stable and a low and stable <jats:styled-content style=\"fixed-case\">IOP<\/jats:styled-content> is maintained over time with an acceptable number of complications. In particular, patients with viral uveitis and glaucoma should be closely monitored for <jats:styled-content style=\"fixed-case\">IOP<\/jats:styled-content> peaks that may occur during episodes of a flare\u2010up of uveitis, whereas at the other end of the spectrum, patients with <jats:styled-content style=\"fixed-case\">JIA<\/jats:styled-content> seem much more prone to hypotony maculopathy.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aos.13489","type":"journal-article","created":{"date-parts":[[2017,9,18]],"date-time":"2017-09-18T15:01:03Z","timestamp":1505746863000},"page":"24-30","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":31,"title":["Outcomes of severe uveitic glaucoma treated with Baerveldt implant: can blindness be prevented?"],"prefix":"10.1111","volume":"96","author":[{"given":"Annelie N.","family":"Tan","sequence":"first","affiliation":[{"name":"Maastricht University Medical Centre University Eye Clinic Maastricht The Netherlands"},{"name":"Department of Ophthalmology Leiden University Medical Centre Leiden The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michiel F.","family":"Cornelissen","sequence":"additional","affiliation":[{"name":"Maastricht University Medical Centre University Eye Clinic Maastricht The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carroll A. 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