{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T19:11:33Z","timestamp":1762542693016},"reference-count":12,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2017,5,29]],"date-time":"2017-05-29T00:00:00Z","timestamp":1496016000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Ophthalmologica"],"published-print":{"date-parts":[[2018,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>To evaluate the clinical validity of the Rabin cone contrast test (<jats:styled-content style=\"fixed-case\">RCCT<\/jats:styled-content>; Innova Systems, Inc.) in patients with normal phakic\/pseudophakic eyes and severe dichromatic colour vision deficiency (<jats:styled-content style=\"fixed-case\">CVD<\/jats:styled-content>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We evaluated age\u2010related changes in the <jats:styled-content style=\"fixed-case\">RCCT<\/jats:styled-content> scores in 166 phakic eyes and 34 pseudophakic eyes and the <jats:styled-content style=\"fixed-case\">RCCT<\/jats:styled-content> sensitivity and specificity in 28 men with severe dichromatic <jats:styled-content style=\"fixed-case\">CVD<\/jats:styled-content> (10 with protanopia, 18 with deutanopia) and nine age\u2010matched controls. All participants had 20\/20 or better Snellen best\u2010corrected visual acuity (BCVA). The <jats:styled-content style=\"fixed-case\">RCCT<\/jats:styled-content> was used to measure the L, M and S\u2010<jats:styled-content style=\"fixed-case\">CCT<\/jats:styled-content> scores (range, 0\u2013100).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In normal phakic eyes, the mean L, M and S\u2010<jats:styled-content style=\"fixed-case\">CCT<\/jats:styled-content> scores decreased gradually with ageing, with normal levels in patients in the second to seventh decades of life and some below normal in the eighth and ninth decades of life. In normal pseudophakic eyes, the mean L, M and S\u2010<jats:styled-content style=\"fixed-case\">CCT<\/jats:styled-content> scores were normal in patients in the seventh to ninth decades of life. In eyes with severe <jats:styled-content style=\"fixed-case\">CVD<\/jats:styled-content>, the mean L, M and S\u2010<jats:styled-content style=\"fixed-case\">CCT<\/jats:styled-content> scores were, respectively, 31.5\u00a0\u00b1\u00a018.3, 86.0\u00a0\u00b1\u00a012.6 and\u00a098.0\u00a0\u00b1\u00a06.3 in patients with protanopia; 92.8\u00a0\u00b1\u00a010.5, 50.8\u00a0\u00b1\u00a019.6 and 97.8\u00a0\u00b1\u00a05.2 in patients with deutanopia; and 99.4\u00a0\u00b1\u00a01.7, 98.3\u00a0\u00b1\u00a05.0 and 99.4\u00a0\u00b1\u00a01.7 in controls. The <jats:styled-content style=\"fixed-case\">RCCT<\/jats:styled-content> sensitivity and specificity were 100% for diagnosing the <jats:styled-content style=\"fixed-case\">CVD<\/jats:styled-content> type.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The <jats:styled-content style=\"fixed-case\">RCCT<\/jats:styled-content> can be used in non\u2010visually impaired patients up to the seventh decade of life and after cataract surgery in elderly patients. The <jats:styled-content style=\"fixed-case\">RCCT<\/jats:styled-content> is available for <jats:styled-content style=\"fixed-case\">CVD<\/jats:styled-content> screening and typing and the score has a wide distribution range even in patients with severe <jats:styled-content style=\"fixed-case\">CVD<\/jats:styled-content>.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aos.13495","type":"journal-article","created":{"date-parts":[[2017,5,29]],"date-time":"2017-05-29T11:18:41Z","timestamp":1496056721000},"update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Evaluation of clinical validity of the Rabin cone contrast test in normal phakic or pseudophakic eyes and severely dichromatic eyes"],"prefix":"10.1111","volume":"96","author":[{"given":"Masato","family":"Fujikawa","sequence":"first","affiliation":[{"name":"Department of Ophthalmology Shiga University of Medical Science Shiga Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sanae","family":"Muraki","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology Shiga University of Medical Science Shiga Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuichi","family":"Niwa","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology Shiga University of Medical Science Shiga Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masahito","family":"Ohji","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology Shiga University of Medical Science Shiga Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,5,29]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.12-9471"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006324-199101000-00007"},{"key":"e_1_2_5_4_1","first-page":"776","article-title":"Transmission of the ocular media","volume":"1","author":"Boettner EA","year":"1962","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0886-3350(13)80313-6"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0042-6989(97)00382-9"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.14-14079"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-5155(03)00011-X"},{"key":"e_1_2_5_9_1","first-page":"2771","article-title":"Cone\u2010specific measures of human color vision","volume":"37","author":"Rabin J","year":"1996","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0952523804213128"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.10-6283"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.survophthal.2015.11.004"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1364\/JOSAA.14.000953"}],"container-title":["Acta Ophthalmologica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Faos.13495","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/aos.13495","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,23]],"date-time":"2023-09-23T16:51:46Z","timestamp":1695487906000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/aos.13495"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,5,29]]},"references-count":12,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2018,3]]}},"alternative-id":["10.1111\/aos.13495"],"URL":"https:\/\/doi.org\/10.1111\/aos.13495","archive":["Portico"],"relation":{},"ISSN":["1755-375X","1755-3768"],"issn-type":[{"value":"1755-375X","type":"print"},{"value":"1755-3768","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,5,29]]},"assertion":[{"value":"2016-04-30","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-05-02","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-05-29","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}