{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T14:25:45Z","timestamp":1787495145442,"version":"build-2736575974"},"reference-count":25,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2017,9,19]],"date-time":"2017-09-19T00:00:00Z","timestamp":1505779200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Ophthalmologica"],"published-print":{"date-parts":[[2017,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>\n                      To report beta\u2010trace protein (\n                      <jats:italic>\u03b2<\/jats:italic>\n                      <jats:styled-content style=\"fixed-case\">TP<\/jats:styled-content>\n                      ) levels in the subretinal fluid (SRF) of four patients with a macular detachment associated with optic disc pit (\n                      <jats:styled-content style=\"fixed-case\">ODP<\/jats:styled-content>\n                      ).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Four patients with a serous retinal detachment involving the macula was operated by pars plana vitrectomy (\n                      <jats:styled-content style=\"fixed-case\">PPV<\/jats:styled-content>\n                      ) with C\n                      <jats:sub>2<\/jats:sub>\n                      F\n                      <jats:sub>6<\/jats:sub>\n                      gas tamponade and peeling of internal limiting membrane (\n                      <jats:styled-content style=\"fixed-case\">ILM<\/jats:styled-content>\n                      ). Patients with a follow\u2010up period exceeding one year postoperatively were included in the study. The\n                      <jats:styled-content style=\"fixed-case\">SRF<\/jats:styled-content>\n                      was drained using a fine cannula without laser photocoagulation, and the samples were analysed using particle\u2010enhancing nephelometry. The levels of\n                      <jats:italic>\u03b2<\/jats:italic>\n                      <jats:styled-content style=\"fixed-case\">TP<\/jats:styled-content>\n                      were compared to 20 routine cerebrospinal fluid (\n                      <jats:styled-content style=\"fixed-case\">CSF<\/jats:styled-content>\n                      ) samples.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      In four of the five samples from\n                      <jats:styled-content style=\"fixed-case\">SRF<\/jats:styled-content>\n                      had relatively low\n                      <jats:italic>\u03b2<\/jats:italic>\n                      <jats:styled-content style=\"fixed-case\">TP<\/jats:styled-content>\n                      levels, with a mean concentration of 6.6\u00a0mg\/l (range 2.0 to 23.1\u00a0mg\/l) compared to 16.0\u00a0mg\/l (range 6.3\u201026.8\u00a0mg\/l) in\n                      <jats:styled-content style=\"fixed-case\">CSF<\/jats:styled-content>\n                      . The only\n                      <jats:styled-content style=\"fixed-case\">SRF<\/jats:styled-content>\n                      sample within the range corresponding to normal\n                      <jats:styled-content style=\"fixed-case\">CSF<\/jats:styled-content>\n                      was the first sample from patient 4, and the analysis of the renewed aspirate during the second operation was 2.8\u00a0mg\/l. Postoperatively, the regression of\n                      <jats:styled-content style=\"fixed-case\">SRF<\/jats:styled-content>\n                      was slow, but regression of\n                      <jats:styled-content style=\"fixed-case\">SRF<\/jats:styled-content>\n                      in the foveal region took place in all cases; however, visual acuity (VA) was improved in only half of the patients.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      The results from the analysed\n                      <jats:styled-content style=\"fixed-case\">SRF<\/jats:styled-content>\n                      regarding\n                      <jats:italic>\u03b2<\/jats:italic>\n                      <jats:styled-content style=\"fixed-case\">TP<\/jats:styled-content>\n                      concentration in these patients indicate that the SRF in\n                      <jats:styled-content style=\"fixed-case\">ODP<\/jats:styled-content>\n                      is not identical to\n                      <jats:styled-content style=\"fixed-case\">CSF<\/jats:styled-content>\n                      , as the concentrations of\n                      <jats:italic>\u03b2<\/jats:italic>\n                      <jats:styled-content style=\"fixed-case\">TP<\/jats:styled-content>\n                      differ.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/aos.13527","type":"journal-article","created":{"date-parts":[[2017,9,19]],"date-time":"2017-09-19T09:02:36Z","timestamp":1505811756000},"page":"815-819","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Levels of beta\u2010trace protein in optic disc pit with macular 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