{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T11:10:17Z","timestamp":1778843417523,"version":"3.51.4"},"reference-count":16,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2017,11,1]],"date-time":"2017-11-01T00:00:00Z","timestamp":1509494400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001700","name":"Ministry of Education, Culture, Sports, Science and Technology","doi-asserted-by":"publisher","award":["26462689"],"award-info":[{"award-number":["26462689"]}],"id":[{"id":"10.13039\/501100001700","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Ophthalmologica"],"published-print":{"date-parts":[[2018,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>To investigate whether there are differences in retinal oxygen saturation in upper and lower visual field hemispheres in primary open\u2010angle glaucoma (<jats:styled-content style=\"fixed-case\">POAG<\/jats:styled-content>) and in normal\u2010tension glaucoma (<jats:styled-content style=\"fixed-case\">NTG<\/jats:styled-content>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This study enrolled <jats:styled-content style=\"fixed-case\">POAG<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">NTG<\/jats:styled-content> patients exhibiting differences between the upper and lower total deviation (<jats:styled-content style=\"fixed-case\">TD<\/jats:styled-content>) that were either more than 10 or &lt;5\u00a0<jats:styled-content style=\"fixed-case\">dB<\/jats:styled-content>. Retinal oxygen saturation measurements in these patients with glaucoma were performed by a non\u2010invasive spectrophotometric retinal oximeter. The Student's <jats:italic>t<\/jats:italic>\u2010test was used for statistical analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Evaluations of the worse and better hemifields in the patients with <jats:styled-content style=\"fixed-case\">POAG<\/jats:styled-content> who exhibited differences in the upper and lower hemifield <jats:styled-content style=\"fixed-case\">TD<\/jats:styled-content> that was &lt;5\u00a0<jats:styled-content style=\"fixed-case\">dB<\/jats:styled-content> (<jats:italic>n<\/jats:italic>\u00a0=\u00a025) showed that there were no statistically significant differences for the retinal venous saturation of oxygen (SaO<jats:sub>2<\/jats:sub>). However, there was a higher mean SaO<jats:sub>2<\/jats:sub> in the worse (57.0\u00a0\u00b1\u00a07.5%) versus the better (54.3\u00a0\u00b1\u00a07.0%) hemifield in the patients with <jats:styled-content style=\"fixed-case\">NTG<\/jats:styled-content> (<jats:italic>n<\/jats:italic>\u00a0=\u00a022; p<jats:italic>\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.007). Evaluations of the patients with more than a 10\u2010<jats:styled-content style=\"fixed-case\">dB<\/jats:styled-content> difference in the upper and lower hemifield <jats:styled-content style=\"fixed-case\">TD<\/jats:styled-content> showed statistically significant differences for the retinal venous SaO<jats:sub>2<\/jats:sub> in the venous vessels between the <jats:styled-content style=\"fixed-case\">POAG<\/jats:styled-content> (<jats:italic>n<\/jats:italic>\u00a0=\u00a019) and the <jats:styled-content style=\"fixed-case\">NTG<\/jats:styled-content> (<jats:italic>n<\/jats:italic>\u00a0=\u00a026) patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Although there was no significant difference in retinal SaO<jats:sub>2<\/jats:sub> in the venules between the better and worse hemifield when the difference between the better and worse hemifield in the patients with <jats:styled-content style=\"fixed-case\">POAG<\/jats:styled-content> was &lt;5\u00a0<jats:styled-content style=\"fixed-case\">dB<\/jats:styled-content>, there was a higher SaO<jats:sub>2<\/jats:sub> in the venous vessels in the worse hemifield in the patients with <jats:styled-content style=\"fixed-case\">NTG<\/jats:styled-content>.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aos.13575","type":"journal-article","created":{"date-parts":[[2017,11,1]],"date-time":"2017-11-01T12:06:38Z","timestamp":1509537998000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Oxygen venular saturation correlates with a functional loss in primary open\u2010angle glaucoma and normal\u2010tension glaucoma patients"],"prefix":"10.1111","volume":"96","author":[{"given":"Takeru","family":"Shimazaki","sequence":"first","affiliation":[{"name":"Department of Ophthalmology Kagawa University Faculty of Medicine Kagawa 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