{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T19:12:50Z","timestamp":1762542770485,"version":"3.37.3"},"reference-count":19,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2017,11,30]],"date-time":"2017-11-30T00:00:00Z","timestamp":1512000000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Ophthalmologica"],"published-print":{"date-parts":[[2018,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>To compare the self\u2010sealing features and dimensional stability between the femtosecond laser (<jats:styled-content style=\"fixed-case\">FL<\/jats:styled-content>) and manual knife corneal incision.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>For the clinical study, 29 consecutive eyes from 29 patients and 28 eyes from 28 patients who underwent cataract surgery with <jats:styled-content style=\"fixed-case\">FL<\/jats:styled-content> corneal incision and manual knife incision, respectively, were enrolled. Immediately after cataract surgery, the self\u2010sealing features of the corneal incisions were evaluated. Scanning electron microscopy (<jats:styled-content style=\"fixed-case\">SEM<\/jats:styled-content>) images were obtained. For the experimental study, clear corneal incisions with a knife or <jats:styled-content style=\"fixed-case\">FL<\/jats:styled-content> with different energy settings (3, 6 and 9\u00a0<jats:italic>\u03bc<\/jats:italic>J) were created in fresh porcine eyes, followed by a stress test. The incision width was measured before and after the stress test.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In the clinical study, the knife group had a higher self\u2010sealing score (0.60\u00a0\u00b1\u00a00.49 points) than the <jats:styled-content style=\"fixed-case\">FL<\/jats:styled-content> group (0.17\u00a0\u00b1\u00a00.38 points). In the experimental study, the deformation rate in the knife incision (5.04\u00a0\u00b1\u00a01.93) was significantly lower than that in the <jats:styled-content style=\"fixed-case\">FL<\/jats:styled-content> with any energy. The deformation rate in the 9\u00a0<jats:italic>\u03bc<\/jats:italic>J (12.98\u00a0\u00b1\u00a02.76) was significantly higher than in the 3\u00a0<jats:italic>\u03bc<\/jats:italic>J (8.54\u00a0\u00b1\u00a02.38) and 6\u00a0<jats:italic>\u03bc<\/jats:italic>J (8.82\u00a0\u00b1\u00a02.85) <jats:styled-content style=\"fixed-case\">FL<\/jats:styled-content> energies. Scanning electron microscopy (SEM) images revealed that the corneal stromal surface of the knife incision was smoother than that of the <jats:styled-content style=\"fixed-case\">FL<\/jats:styled-content>. Higher energy <jats:styled-content style=\"fixed-case\">FL<\/jats:styled-content> showed more irregular surfaces.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Higher <jats:styled-content style=\"fixed-case\">FL<\/jats:styled-content> energy tended to widen a clear corneal incision when\u00a0mechanical stress was applied. The histological differences at the inner\u00a0tunnel surface may cause differences in wound stability of the corneal incision.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aos.13634","type":"journal-article","created":{"date-parts":[[2017,11,30]],"date-time":"2017-11-30T07:32:38Z","timestamp":1512027158000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Clinical and ex\u00a0vivo laboratory comparison of the self\u2010sealing properties and dimensional stability between the femtosecond laser and manual clear corneal incisions"],"prefix":"10.1111","volume":"96","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5016-0155","authenticated-orcid":false,"given":"Takashi","family":"Kojima","sequence":"first","affiliation":[{"name":"Department of Ophthalmology Japanese Red Cross Gifu Hospital Gifu Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mari","family":"Takagi","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology Japanese Red Cross Gifu Hospital Gifu Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kei","family":"Ichikawa","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology Japanese Red Cross Gifu Hospital Gifu Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rie","family":"Horai","sequence":"additional","affiliation":[{"name":"Chukyo Medical, CO., INC. Nagoya Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yukihiro","family":"Sakai","sequence":"additional","affiliation":[{"name":"Chukyo Eye Clinic Nagoya Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshiki","family":"Tanaka","sequence":"additional","affiliation":[{"name":"Chukyo Medical, CO., INC. Nagoya Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akeno","family":"Tamaoki","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology Japan Community Healthcare Organization Chukyo Hospital Nagoya Japan"},{"name":"Shinshu University Interdisciplinary Graduate School of Science and Technology Nagano Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazuo","family":"Ichikawa","sequence":"additional","affiliation":[{"name":"Chukyo Eye Clinic Nagoya Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,11,30]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2012.11.045"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2014.10.001"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0071731"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/ICL.0000000000000119"},{"key":"e_1_2_5_6_1","doi-asserted-by":"crossref","first-page":"1442","DOI":"10.1016\/j.jcrs.2013.07.002","article-title":"On the way to zero phaco","volume":"39","author":"Dick HB","year":"2013","journal-title":"J Cataract Refract Surg"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1080\/02713680601077145"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.3928\/1081-597X-20071001-11"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.exer.2008.02.006"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2013.11.028"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/ICL.0000000000000262"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0420.2005.00419.x"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.3928\/1081597X-20131217-03"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2014.02.015"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.15-18248"},{"key":"e_1_2_5_16_1","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/S0886-3350(02)01483-9","article-title":"Bacterial endophthalmitis after small\u2010incision cataract surgery. effect of incision placement and intraocular lens type","volume":"29","author":"Nagaki Y","year":"2003","journal-title":"J Cataract Refract Surg"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.3928\/1081597X-20110607-01"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.4103\/0971-6203.42763"},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2004.10.057"},{"key":"e_1_2_5_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9290(00)00219-0"}],"container-title":["Acta Ophthalmologica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Faos.13634","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/aos.13634","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,18]],"date-time":"2023-09-18T12:33:24Z","timestamp":1695040404000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/aos.13634"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,11,30]]},"references-count":19,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2018,6]]}},"alternative-id":["10.1111\/aos.13634"],"URL":"https:\/\/doi.org\/10.1111\/aos.13634","archive":["Portico"],"relation":{},"ISSN":["1755-375X","1755-3768"],"issn-type":[{"type":"print","value":"1755-375X"},{"type":"electronic","value":"1755-3768"}],"subject":[],"published":{"date-parts":[[2017,11,30]]},"assertion":[{"value":"2017-07-05","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-10-12","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-11-30","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}