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Kaplan\u2010Meier survival analyses were performed to evaluate disease progression in relation to diabetes duration, age and year of diabetes onset. HRQ<\/jats:styled-content>oL and its association with DR<\/jats:styled-content> were assessed by the Medical Outcomes Study Short Form 36 (SF<\/jats:styled-content>\u201036) questionnaire.<\/jats:p><\/jats:sec>Results<\/jats:title>A total of 237 DM<\/jats:styled-content>1 patients were included. Mean age at inclusion was 34\u00a0years (range, 4\u201375\u00a0years), and mean diabetes duration was 19\u00a0years (range, 5\u00a0months\u201363\u00a0years). A total of 145 patients (61%) had DR<\/jats:styled-content>. Sixty\u2010two patients (26%) had mild, 39 (16%) moderate and 13 (5%) severe nonproliferative DR<\/jats:styled-content>, while 31 (13%) had proliferative DR<\/jats:styled-content>. The prevalence of DMO<\/jats:styled-content> was 8%. The most important risk factors predicting severity of DR<\/jats:styled-content> were diabetes duration (p\u00a0<\/jats:italic><\u00a0<\/jats:italic>0.0001) and HbA1c level (p\u00a0<\/jats:italic><\u00a0<\/jats:italic>0.0001). Neuropathy (p\u00a0<\/jats:italic>=\u00a0<\/jats:italic>0.006), nephropathy (p\u00a0<\/jats:italic>=\u00a0<\/jats:italic>0.004) and male gender (p\u00a0<\/jats:italic>=\u00a0<\/jats:italic>0.02) were also significant predictors of DR<\/jats:styled-content>. Compared to normative SF<\/jats:styled-content>\u201036 data, there was a linear trend of decreasing HRQ<\/jats:styled-content>oL with increasing severity of DR<\/jats:styled-content> that was statistically significant for the four physical dimension scores.<\/jats:p><\/jats:sec>Conclusion<\/jats:title>The prevalence of DR<\/jats:styled-content> in DM<\/jats:styled-content>1 was largely within the range of previous reports. Diabetes duration, HbA1c level, neuropathy, nephropathy and male gender were all significant predictors of DR<\/jats:styled-content> severity. The patients with more severe DR<\/jats:styled-content> had lower HRQ<\/jats:styled-content>oL.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aos.13654","type":"journal-article","created":{"date-parts":[[2018,1,25]],"date-time":"2018-01-25T14:58:44Z","timestamp":1516892324000},"page":"465-474","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":32,"title":["Diabetic retinopathy in type 1 diabetes patients in Western Norway"],"prefix":"10.1111","volume":"96","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1227-7843","authenticated-orcid":false,"given":"Ragnhild W.","family":"Jansson","sequence":"first","affiliation":[{"name":"Department of Clinical Medicine Section\u00a0of Ophthalmology University of Bergen Bergen Norway"},{"name":"Department of Ophthalmology Haukeland University Hospital Bergen Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karl Ove","family":"Hufthammer","sequence":"additional","affiliation":[{"name":"Centre for Clinical Research Haukeland University Hospital Bergen Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4783-2974","authenticated-orcid":false,"given":"J\u00f8rgen","family":"Krohn","sequence":"additional","affiliation":[{"name":"Department of Clinical Medicine Section\u00a0of Ophthalmology University of Bergen Bergen Norway"},{"name":"Department of Ophthalmology Haukeland University Hospital Bergen Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,1,25]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfp709"},{"issue":"1","key":"e_1_2_5_3_1","doi-asserted-by":"crossref","first-page":"S39","DOI":"10.2337\/dc16-S008","article-title":"Glycemic targets Sec. 5. 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