{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,21]],"date-time":"2026-01-21T20:20:23Z","timestamp":1769026823217,"version":"3.49.0"},"reference-count":27,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2018,3,25]],"date-time":"2018-03-25T00:00:00Z","timestamp":1521936000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Japan National Society for the Prevention of Blindness and Japan Ophthalmologists Association"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Ophthalmologica"],"published-print":{"date-parts":[[2018,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purposes<\/jats:title><jats:p>To assess <jats:italic>\u03b2<\/jats:italic>\u2010zone of peripapillary atrophy (<jats:italic>\u03b2<\/jats:italic>\u2010PPA) and its relationship between systemic and ocular factors, especially glaucoma, in a Japanese population.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Fundus photographs obtained from 2129 normal, 84 primary open\u2010angle glaucoma (POAG) and 10 primary angle closure glaucoma subjects from 3021 participants aged 40\u00a0years or older in the Tajimi Study were analysed planimetrically. If both eyes of a subject met inclusion criteria, one eye was randomly chosen.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The presence rates of <jats:italic>\u03b2<\/jats:italic>\u2010PPA were 54.7 and 77.4% (p\u00a0&lt;\u00a00.001) and <jats:italic>\u03b2<\/jats:italic>\u2010PPA area averaged 0.67 and 1.06\u00a0mm<jats:sup>2<\/jats:sup> (p\u00a0&lt;\u00a00.001), in normal and POAG eyes, respectively. Myopia was closely related to disc ovality and <jats:italic>\u03b2<\/jats:italic>\u2010PPA. In normal eyes, logistic analysis showed that the presence of <jats:italic>\u03b2<\/jats:italic>\u2010PPA was correlated with older age, female gender, myopic refraction, thicker central corneal thickness (CCT), greater disc ovality and disc centre to fovea (disc\u2010fovea) distance and lower intraocular pressure (IOP) (p\u00a0=\u00a00.039\u00a0~\u00a0&lt;0.001); and multiple regression analysis showed that <jats:italic>\u03b2<\/jats:italic>\u2010PPA area was correlated with older age, myopic refraction, greater disc area and ovality, disc\u2010fovea distance and lower IOP (p\u00a0=\u00a00.004\u00a0~\u00a0&lt;0.001) after adjusting other factors.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The presence and size of <jats:italic>\u03b2<\/jats:italic>\u2010PPA in normal eyes were correlated with older age, greater disc ovality and disc\u2010fovea distance and lower IOP. Further, its presence was associated with female gender, thicker CCT and its size with greater disc area. <jats:italic>\u03b2<\/jats:italic>\u2010zone of peripapillary atrophy (<jats:italic>\u03b2<\/jats:italic>\u2010PPA) was also associated with POAG. These results provide reference data of the <jats:italic>\u03b2<\/jats:italic>\u2010PPA in a Japanese population and possibly indicate clinical importance of <jats:italic>\u03b2<\/jats:italic>\u2010PPA in glaucoma clinic.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aos.13702","type":"journal-article","created":{"date-parts":[[2018,3,25]],"date-time":"2018-03-25T15:19:53Z","timestamp":1521991193000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Beta\u2010peripapillary atrophy of the optic disc and its determinants in Japanese eyes: a population\u2010based study"],"prefix":"10.1111","volume":"96","author":[{"given":"Naomi","family":"Mataki","sequence":"first","affiliation":[{"name":"Department of Ophthalmology University of Tokyo Graduate School of Medicine Tokyo Japan"},{"name":"Kanto Central Hospital of the Mutual Aid Association of Public School Teachers Setagaya Tokyo Japan"},{"name":"Tajimi Iwase Eye Clinic Tajimi 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