{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T09:22:04Z","timestamp":1775035324267,"version":"3.50.1"},"reference-count":35,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2018,8,29]],"date-time":"2018-08-29T00:00:00Z","timestamp":1535500800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Ophthalmologica"],"published-print":{"date-parts":[[2018,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>To temporally study the healing of conjunctival autografts in consecutive patients following pterygium surgery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A case\u2010cohort observational study. Thirty\u2010two eyes of 28 patients who underwent pterygium surgery were included. All eyes had pterygium excision with conjunctival autografts. Twenty\u2010seven eyes of 24 patients underwent excision of primary pterygium while five eyes of four patients had surgery for recurrent pterygium. All grafts were attached using fibrin glue. Mitomycin\u2010C 0.04% was used intraoperatively in 25 eyes. All eyes were followed up at 1, 2, 4, 8, 12\u00a0weeks and 6\u00a0months postoperatively. Photographs were taken at each visit to monitor graft vessels, re\u2010perfusion and healing. Main outcome measures were graft loss; re\u2010perfusion of grafts and appearance and resolution of oedema, transudation and haemorrhage; approximation of graft edges to host bed and changes at donor site.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>No graft tissue was lost. In all eyes, healing of autografts started with graft swelling due to oedema and transudation followed by re\u2010perfusion injury, which manifested as swelling, variable vessels calibre, patchy or diffuse haemorrhage occurring within first week and resolving by fourth postoperative week. Graft vessels anastomose with vessels in surrounding conjunctiva and underlying episclera to re\u2010establish blood circulation. Retraction of graft edges from surrounding conjunctiva was uncommon with rapid epithelialization of exposed (epi)sclera.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Conjunctival autografts in pterygium surgery follow a consistent healing pattern dominated by re\u2010perfusion injury in early postoperative days. This produces dramatic changes in the autograft for which patients should be counselled before surgery. Conjunctival autografts are not at risk of falling off, losing epithelial cover or undergoing necrosis.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aos.13794","type":"journal-article","created":{"date-parts":[[2018,8,30]],"date-time":"2018-08-30T06:41:36Z","timestamp":1535611296000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Healing of autologous conjunctival grafts in pterygium surgery"],"prefix":"10.1111","volume":"96","author":[{"given":"Noha","family":"Ghoz","sequence":"first","affiliation":[{"name":"Academic Section\u00a0of Ophthalmology Division of Clinical Neuroscience University of Nottingham Nottingham UK"},{"name":"Department of Ophthalmology Nottingham University Hospitals NHS Trust Nottingham 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