{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,14]],"date-time":"2026-02-14T05:28:54Z","timestamp":1771046934816,"version":"3.50.1"},"reference-count":13,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2018,4,19]],"date-time":"2018-04-19T00:00:00Z","timestamp":1524096000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Ophthalmologica"],"published-print":{"date-parts":[[2018,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>The major goal of this study was to test the hypothesis that in patients with peripheral hypertrophic subepithelial corneal opacification (<jats:styled-content style=\"fixed-case\">PHSCO<\/jats:styled-content>), visualization of corneal vessels is better with optical coherence tomography angiography (<jats:styled-content style=\"fixed-case\">OCTA<\/jats:styled-content>) than with conventional slit lamp microphotography.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients with <jats:styled-content style=\"fixed-case\">PHSCO<\/jats:styled-content> were included in this prospective study. The corneal findings were photographed using a slit lamp camera (Haag Streit <jats:styled-content style=\"fixed-case\">BM<\/jats:styled-content> 900<jats:sup>\u00ae<\/jats:sup>) and visualized with anterior\u2010segment <jats:styled-content style=\"fixed-case\">OCT<\/jats:styled-content> (Optovue <jats:styled-content style=\"fixed-case\">XR<\/jats:styled-content> Avanti, Fremont, California, <jats:styled-content style=\"fixed-case\">USA<\/jats:styled-content>). Additionally, <jats:styled-content style=\"fixed-case\">OCTA<\/jats:styled-content> with the Angiovue Imaging\u2122 System was performed in the area of <jats:styled-content style=\"fixed-case\">PHSCO<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Thirty\u2010four eyes of 19 patients (26% male and 74% female) with <jats:styled-content style=\"fixed-case\">PHSCO<\/jats:styled-content> were included in this study. In 21 eyes, vascularization in the area of <jats:styled-content style=\"fixed-case\">PHSCO<\/jats:styled-content> was visualized with the Angiovue\u2010<jats:styled-content style=\"fixed-case\">OCT<\/jats:styled-content>, whereas only 10 eyes presented vessels in slit lamp photographs.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Optical coherence tomography angiography allows better visualization of corneal neovascularization than slit lamp photography in patients with <jats:styled-content style=\"fixed-case\">PHSCO<\/jats:styled-content>. Corneal opacifications were found predominantly nasally, which was reflected by a local enlargement of corneal thickness.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aos.13800","type":"journal-article","created":{"date-parts":[[2018,4,19]],"date-time":"2018-04-19T15:13:56Z","timestamp":1524150836000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Visualization of corneal vascularization in peripheral hypertrophic subepithelial corneal opacification with <scp>OCT<\/scp> angiography"],"prefix":"10.1111","volume":"96","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8015-846X","authenticated-orcid":false,"given":"Jana C.","family":"Riedl","sequence":"first","affiliation":[{"name":"Department of Ophthalmology University Medical Center Johannes Gutenberg\u2010University Mainz 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