{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,18]],"date-time":"2026-07-18T00:49:47Z","timestamp":1784335787389,"version":"3.55.0"},"reference-count":31,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2018,10,3]],"date-time":"2018-10-03T00:00:00Z","timestamp":1538524800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Ophthalmologica"],"published-print":{"date-parts":[[2019,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>A descriptive study on visual fields, as part of a 50\u2010year follow\u2010up of high myopia in an unselected cohort\u2010based Danish sample, now aged 66\u00a0years.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In a Copenhagen 1948 birth cohort (<jats:italic>n\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>9243), 39 individuals aged 14\u00a0years were identified with myopia of at least \u22126\u00a0D, and with regular clinical follow\u2010ups since then. In 2002 (<jats:italic>n\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>34, age 54\u00a0years) and 2008 (<jats:italic>n\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>32, age 60), the individual ambulatory visual field was outlined by kinetic Goldmann large object perimetry (IV or V,4e). At age 66\u00a0years, 28 attended for the 2014\u20132015 follow\u2010up, at which smaller Goldmann objects (<jats:styled-content style=\"fixed-case\">II<\/jats:styled-content> and I,4e) were added, further to identify relative defects.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Repeated <jats:italic>large object<\/jats:italic> perimetry disclosed statistically significant general peripheral narrowing over the 12\u201313\u2010year test period, though slight and without practical implications. Two new cases showing absolute defects were however added to the three already known. The addition of <jats:italic>small Goldmann objects<\/jats:italic> disclosed relative defects in another eight participants, in some to suggest a refraction\u2010related pattern (fundus ectasia; uncorrected high myopia). However, comparing eyes with and without defects, statistical importance could not be attached to the degree of myopia, fundus ectasia or optic disc morphology (<jats:italic>\u03c7<\/jats:italic><jats:sup>2<\/jats:sup>, n.s.).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>(i) Serial large object Goldmann isopters over the \u2018senior\u2019 decade up to age 66 demonstrated a slight general peripheral narrowing by age of visual fields in high myopia. (ii) Overall 42% of the participants had absolute or relative defects (in 5 and 8, respectively), however, without socio\u2010visual consequences when binocular. (iii) Visual field loss by age still appears a minor issue in clinically unselected high myopia.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aos.13820","type":"journal-article","created":{"date-parts":[[2018,10,5]],"date-time":"2018-10-05T18:28:12Z","timestamp":1538764092000},"page":"36-43","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["The Longitudinal Danish High Myopia Study, Cohort 1948: at age 66\u00a0years visual ability is only occasionally affected by visual field defects"],"prefix":"10.1111","volume":"97","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9801-589X","authenticated-orcid":false,"given":"Hans C.","family":"Fledelius","sequence":"first","affiliation":[{"name":"Copenhagen University Eye Departments, Rigshospitalet Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nina","family":"Jacobsen","sequence":"additional","affiliation":[{"name":"Copenhagen University Eye Departments, Rigshospitalet Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao Q.","family":"Li","sequence":"additional","affiliation":[{"name":"Copenhagen University Eye Departments, Rigshospitalet Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ernst","family":"Goldschmidt","sequence":"additional","affiliation":[{"name":"Danish Myopia Institute Esperg\u00e6rde Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,10,3]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-4-431-66959-3_73"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(00)00497-8"},{"key":"e_1_2_5_4_1","first-page":"680","article-title":"Gesichtsfeldver\u00e4nderungen bei hochgradig Myopen","volume":"145","author":"Blatt N","year":"1964","journal-title":"Klin Monatsbl Augenheilkd"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.08-2135"},{"key":"e_1_2_5_6_1","volume-title":"The myopias: basic science and clinical management","author":"Curtin BJ","year":"1985"},{"key":"e_1_2_5_7_1","first-page":"85","volume-title":"Textbook of ophthalmology","author":"Duke\u2010Elder S","year":"1938"},{"key":"e_1_2_5_8_1","first-page":"3","article-title":"The visual field in normal subjects (thesis)","volume":"169","author":"Egge K","year":"1984","journal-title":"Acta Ophthalmol suppl"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0420.2003.00023.x"},{"key":"e_1_2_5_10_1","first-page":"006","article-title":"F\u00a0\u00d7\u00a0\u03bb\u00a0=\u00a0v. 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