{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T04:26:40Z","timestamp":1772080000317,"version":"3.50.1"},"reference-count":34,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2018,9,21]],"date-time":"2018-09-21T00:00:00Z","timestamp":1537488000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Ophthalmologica"],"published-print":{"date-parts":[[2019,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>To investigate whether the peripheral thinning and shrinking of the iris as induced with Argon laser peripheral iridoplasty (<jats:styled-content style=\"fixed-case\">ALPI<\/jats:styled-content>) has an effect on intraocular pressure (<jats:styled-content style=\"fixed-case\">IOP<\/jats:styled-content>), angle structure and 3\u2010D anterior segment (AS) morphology in Caucasians with chronic primary angle\u2010closure (<jats:styled-content style=\"fixed-case\">PAC<\/jats:styled-content>) and primary angle\u2010closure glaucoma (<jats:styled-content style=\"fixed-case\">PACG<\/jats:styled-content>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Twenty\u2010four eyes of 24 patients (age 67.7\u00a0\u00b1\u00a08.9\u00a0years; seven males; 17 females) diagnosed with <jats:styled-content style=\"fixed-case\">PAC<\/jats:styled-content> (<jats:italic>n<\/jats:italic>\u00a0=\u00a010) or <jats:styled-content style=\"fixed-case\">PACG<\/jats:styled-content> (<jats:italic>n<\/jats:italic>\u00a0=\u00a014) were assigned for <jats:styled-content style=\"fixed-case\">ALPI<\/jats:styled-content> prior to laser peripheral iridotomy (<jats:styled-content style=\"fixed-case\">LPI<\/jats:styled-content>) and consecutively enrolled in this prospective interventional study. Intraocular pressure (<jats:styled-content style=\"fixed-case\">IOP<\/jats:styled-content>) was measured with Goldmann applanation tonometry, angle structure with gonioscopy using the Shaffer grading system and AS morphology with the Pentacam rotating Scheimpflug camera prior to and 3\u00a0months after <jats:styled-content style=\"fixed-case\">ALPI<\/jats:styled-content>. Intraocular pressure (<jats:styled-content style=\"fixed-case\">IOP<\/jats:styled-content>)\u2010lowering medication was not changed during follow\u2010up.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Intraocular pressure (<jats:styled-content style=\"fixed-case\">IOP<\/jats:styled-content>) changed statistically significantly from 18.8\u00a0\u00b1\u00a03.6 to 14.7\u00a0\u00b1\u00a03.1\u00a0mmHg (p\u00a0&lt;\u00a00.001). Gonioscopy showed a statistically significant angle widening in all four quadrants: nasally from Shaffer 1.04\u00a0\u00b1\u00a00.98 to 2.54\u00a0\u00b1\u00a01.1 (p\u00a0&lt;\u00a00.001), superiorly from 0.39\u00a0\u00b1\u00a00.66 to 1.58\u00a0\u00b1\u00a01.21 (p\u00a0&lt;\u00a00.001), temporally from 0.87\u00a0\u00b1\u00a01.01 to 2.17\u00a0\u00b1\u00a01.24 (p\u00a0=\u00a00.001) and inferiorly from 1.22\u00a0\u00b1\u00a00.74 to 2.75\u00a0\u00b1\u00a00.9 (p\u00a0&lt;\u00a00.001). Pentacam parameters like anterior chamber depth, volume and angle did not increase statistically significantly.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Argon laser peripheral iridoplasty (<jats:styled-content style=\"fixed-case\">ALPI<\/jats:styled-content>) is a safe and effective procedure for reducing appositional angle\u2010closure and thus <jats:styled-content style=\"fixed-case\">IOP<\/jats:styled-content> in nonacute <jats:styled-content style=\"fixed-case\">PAC<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">PACG<\/jats:styled-content> patients.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aos.13878","type":"journal-article","created":{"date-parts":[[2018,9,22]],"date-time":"2018-09-22T01:16:11Z","timestamp":1537578971000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Argon laser peripheral iridoplasty for chronic primary angle\u2010closure and angle\u2010closure glaucoma in caucasians"],"prefix":"10.1111","volume":"97","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4400-6004","authenticated-orcid":false,"given":"Karin R","family":"Pillunat","sequence":"first","affiliation":[{"name":"Department of Ophthalmology Medical Faculty Carl Gustav Carus Technische Universit\u00e4t Dresden Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eberhard","family":"Spoerl","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology Medical Faculty Carl Gustav Carus Technische Universit\u00e4t Dresden Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Johanna","family":"Orphal","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology Medical Faculty Carl Gustav Carus Technische Universit\u00e4t Dresden Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lutz E","family":"Pillunat","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology Medical Faculty Carl Gustav Carus Technische Universit\u00e4t Dresden Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,9,21]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2009.10.030"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(16)30956-4"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1159\/000267854"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(00)00022-1"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjophthalmol-2016-308720"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0039-6257(05)80022-0"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjophthalmol-2011-301189"},{"key":"e_1_2_5_9_1","unstructured":"FosterPJ(2006):Angle closure and angle closure glaucoma. 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