{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,6]],"date-time":"2026-07-06T23:38:56Z","timestamp":1783381136183,"version":"3.54.6"},"reference-count":27,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2018,10,3]],"date-time":"2018-10-03T00:00:00Z","timestamp":1538524800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Hospital Sacro Cuore - Don Calabria"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Ophthalmologica"],"published-print":{"date-parts":[[2019,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>To describe the change in the retinal morphology after full macular translocation (<jats:styled-content style=\"fixed-case\">FMT<\/jats:styled-content>) for exudative age\u2010related macular degeneration (<jats:styled-content style=\"fixed-case\">AMD<\/jats:styled-content>) and identify predictive factors for the visual outcome.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>All patients who underwent <jats:styled-content style=\"fixed-case\">FMT<\/jats:styled-content> from December 2008 through July 2013 were selected. Exclusion criteria were <jats:styled-content style=\"fixed-case\">FMT<\/jats:styled-content> for other disease than <jats:styled-content style=\"fixed-case\">AMD<\/jats:styled-content>, age &lt;60\u00a0years, &lt;12\u00a0months of follow\u2010up or no available images. Spectral domain optical coherence tomography, fundus autofluorescence, fluorangiography and indocyanine green angiography were evaluated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In total, 51 patients were included with a mean follow\u2010up of 30\u00a0months. The presence of the external limiting membrane (<jats:styled-content style=\"fixed-case\">ELM<\/jats:styled-content>) was a significant predictor for a favourable visual outcome 1\u00a0year after <jats:styled-content style=\"fixed-case\">FMT<\/jats:styled-content> (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>\u00a0=\u00a0\u22120.30). Other significant predictive factors were the absence of intraretinal fluid (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>\u00a0=\u00a00.28) and the mixed choroidal neovascularization type (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>\u00a0=\u00a0\u22120.47), whereas nonresponders (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>\u00a0=\u00a00.41) and fibrotic lesions (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>\u00a0=\u00a00.35) were less likely to have a good visual function after surgery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Full macular translocation (<jats:styled-content style=\"fixed-case\">FMT<\/jats:styled-content>), that permits to relocate the diseased macula onto an area of unaffected retinal pigment epithelial and choroid, can restore the anatomy and visual function in some patients with <jats:styled-content style=\"fixed-case\">AMD<\/jats:styled-content> when the outer retina layers are not irreversibly damaged. The presence of the <jats:styled-content style=\"fixed-case\">ELM<\/jats:styled-content> seems to be the most reliable factor in predicting the functional outcome.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aos.13880","type":"journal-article","created":{"date-parts":[[2018,10,5]],"date-time":"2018-10-05T18:33:59Z","timestamp":1538764439000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Morphological changes in the diseased retina on a healthy choroid\u2010retinal pigment epithelial complex after full macular translocation for exudative age\u2010related macular degeneration"],"prefix":"10.1111","volume":"97","author":[{"given":"Saskia Helena Margaretha","family":"van Romunde","sequence":"first","affiliation":[{"name":"Sacrocuore Hospital Negrar Verona 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