{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T12:33:25Z","timestamp":1790253205121,"version":"4.1.0"},"reference-count":65,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2018,10,11]],"date-time":"2018-10-11T00:00:00Z","timestamp":1539216000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Ophthalmologica"],"published-print":{"date-parts":[[2018,12]]},"abstract":"Abstract<\/jats:title>\n \n Purpose<\/jats:title>\n \n Diabetic retinopathy (\n DR<\/jats:styled-content>\n ) is among the leading causes of visual loss in the working\u2010age population. It is generally accepted that screening of\n DR<\/jats:styled-content>\n is cost\u2010effective and can detect\n DR<\/jats:styled-content>\n before it becomes sight\u2010threatening to allow timely treatment.\n <\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n A group of retinal specialists was formed by the Danish Ophthalmological Society with the aim to formulate contemporary evidence\u2010based guidelines for screening of\n DR<\/jats:styled-content>\n in order to implement these in the Danish screening system.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n We hereby present evidence for\n DR<\/jats:styled-content>\n \u2010screening regarding (1) classification of\n DR<\/jats:styled-content>\n , (2) examination techniques, (3) screening intervals and (4) automated screening. It is our recommendation that the International Clinical Retinopathy Disease Severity Scale should be used to classify\n DR<\/jats:styled-content>\n . As a minimum, mydriatic two\u2010field disc\u2010 and macular\u2010centred images are required. In the case of suspected clinically significant diabetic macular oedema, supplementary optical coherence tomography can increase the diagnostic accuracy. There is solid evidence to support a flexible, individualized screening regimen. In particular, it is possible to prolong screening intervals to 24\u201348\u00a0months for patients with no or mild nonproliferative diabetic retinopathy (\n NPDR<\/jats:styled-content>\n ), but it is also possible to use extended intervals of 12\u201324\u00a0months for patients with moderate\n NPDR<\/jats:styled-content>\n given that these are well\u2010regulated regarding glycaemic control (HbA1c\u00a0\u2264\u00a053\u00a0mmol\/mol) and blood pressure (\u2264130\/80\u00a0mmHg). Automated screening of\n DR<\/jats:styled-content>\n is encouraging but is not ready for implementation at present.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n \n Danish evidenced\u2010based guidelines for screening of\n DR<\/jats:styled-content>\n support high\u2010quality imaging and allow flexible, individualized screening intervals with a potential for extension to patients with low risk of\n DR<\/jats:styled-content>\n progression.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/aos.13936","type":"journal-article","created":{"date-parts":[[2018,10,12]],"date-time":"2018-10-12T01:40:17Z","timestamp":1539308417000},"page":"763-769","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":76,"title":["Evidence\u2010based Danish guidelines for screening of diabetic retinopathy"],"prefix":"10.1111","volume":"96","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5019-0736","authenticated-orcid":false,"given":"Jakob","family":"Grauslund","sequence":"first","affiliation":[{"name":"Danish Ophthalmological Society Copenhagen Denmark"},{"name":"Department of Ophthalmology Odense University Hospital Odense Denmark"},{"name":"Department of Clinical Research University of Southern Denmark Odense Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nis","family":"Andersen","sequence":"additional","affiliation":[{"name":"Danish Ophthalmological Society Copenhagen Denmark"},{"name":"Organization of Danish Ophthalmologists Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jens","family":"Andresen","sequence":"additional","affiliation":[{"name":"Danish Ophthalmological Society Copenhagen Denmark"},{"name":"Organization of Danish Ophthalmologists Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Per","family":"Flesner","sequence":"additional","affiliation":[{"name":"Danish Ophthalmological Society Copenhagen Denmark"},{"name":"Organization of Danish Ophthalmologists Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Per","family":"Haamann","sequence":"additional","affiliation":[{"name":"Danish Ophthalmological Society Copenhagen Denmark"},{"name":"Organization of Danish Ophthalmologists Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5906-7670","authenticated-orcid":false,"given":"Steffen","family":"Heegaard","sequence":"additional","affiliation":[{"name":"Danish Ophthalmological Society Copenhagen Denmark"},{"name":"Department of Ophthalmology Rigshospitalet\u2010Glostrup Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Larsen","sequence":"additional","affiliation":[{"name":"Danish Ophthalmological Society Copenhagen Denmark"},{"name":"Department of Ophthalmology Rigshospitalet\u2010Glostrup Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caroline Schmidt","family":"Laugesen","sequence":"additional","affiliation":[{"name":"Danish Ophthalmological Society Copenhagen Denmark"},{"name":"Department of Ophthalmology Zealand University Hospital Roskilde Roskilde Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katja","family":"Schielke","sequence":"additional","affiliation":[{"name":"Danish Ophthalmological Society Copenhagen Denmark"},{"name":"Department of Ophthalmology Aalborg University Hospital Aalborg Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jesper","family":"Skov","sequence":"additional","affiliation":[{"name":"Danish Ophthalmological Society Copenhagen Denmark"},{"name":"Organization of Danish Ophthalmologists Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0409-2534","authenticated-orcid":false,"given":"Toke","family":"Bek","sequence":"additional","affiliation":[{"name":"Danish Ophthalmological Society Copenhagen Denmark"},{"name":"Department of Ophthalmology Aarhus University Hospital Aarhus Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,10,11]]},"reference":[{"key":"e_1_2_11_2_1","unstructured":"AAO. 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