{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T14:43:43Z","timestamp":1740149023626,"version":"3.37.3"},"reference-count":25,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2018,12,3]],"date-time":"2018-12-03T00:00:00Z","timestamp":1543795200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100001818","name":"Research to Prevent Blindness","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100001818","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Ophthalmologica"],"published-print":{"date-parts":[[2019,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>To compare visual acuity outcomes of cataract surgery between patients with and without non\u2010glaucomatous optic neuropathies.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Retrospective case\u2010control study of patients with and without optic neuropathies who underwent cataract surgery from 2010 to 2017. For all eyes, the last preoperative best corrected visual acuity (<jats:styled-content style=\"fixed-case\">BCVA<\/jats:styled-content>) and first <jats:styled-content style=\"fixed-case\">BCVA<\/jats:styled-content> greater than 1\u00a0month postoperatively (to ensure sustained refractive stabilization) were recorded in logarithm of the minimum angle of resolution (log<jats:styled-content style=\"fixed-case\">MAR<\/jats:styled-content>) units.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Thirty patients (42 eyes) with optic neuropathies and 30 control patients (42 eyes) underwent uncomplicated cataract surgery. The mean age at surgery was significantly younger in the optic neuropathy group (64 versus 71.2\u00a0years, p<jats:italic>\u00a0<\/jats:italic>&lt;<jats:italic>\u00a0<\/jats:italic>0.01). The mean improvement in visual acuity in the optic neuropathy group was 0.4\u00a0\u00b1\u00a00.6 log<jats:styled-content style=\"fixed-case\">MAR<\/jats:styled-content> units (roughly 4 Snellen lines) from 0.7\u00a0\u00b1\u00a00.8 units preoperatively to 0.3\u00a0\u00b1\u00a00.5 postoperatively. Between the cases and controls, there was no significant difference in preoperative <jats:styled-content style=\"fixed-case\">BCVA<\/jats:styled-content> (p\u00a0=\u00a00.48), postoperative <jats:styled-content style=\"fixed-case\">BCVA<\/jats:styled-content> (p\u00a0=\u00a00.42), or the mean improvement in <jats:styled-content style=\"fixed-case\">BCVA<\/jats:styled-content> (p\u00a0=\u00a00.82). When stratified by optic neuropathy subtype, patients with optic neuropathies secondary to multiple sclerosis (<jats:italic>n<\/jats:italic>\u00a0=\u00a012) or non\u2010arteritic ischaemic optic neuropathy (<jats:italic>n<\/jats:italic>\u00a0=\u00a011) had significant improvement in <jats:styled-content style=\"fixed-case\">BCVA<\/jats:styled-content> postoperatively (p\u00a0&lt;\u00a00.01 and p\u00a0=\u00a00.03, respectively).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Contrary to what may be expected from such a severe ocular comorbidity, our data suggest that the mean <jats:styled-content style=\"fixed-case\">BCVA<\/jats:styled-content> improvement after cataract surgery in patients with non\u2010glaucomatous optic neuropathies was comparable to that of control patients. Cataract surgery may be performed in patients with both optic neuropathies and advanced cataracts with a reasonable preoperative expectation that visual acuity improvement can be significant.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aos.13959","type":"journal-article","created":{"date-parts":[[2018,12,4]],"date-time":"2018-12-04T06:04:10Z","timestamp":1543903450000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Visual acuity after cataract surgery in patients with optic neuropathies"],"prefix":"10.1111","volume":"97","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1887-7519","authenticated-orcid":false,"given":"Sahil","family":"Aggarwal","sequence":"first","affiliation":[{"name":"University of California Irvine School of Medicine Irvine CA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Darren K.","family":"Knight","sequence":"additional","affiliation":[{"name":"Gavin Herbert Eye Institute 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