{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T00:44:26Z","timestamp":1787013866989,"version":"build-2736575974"},"reference-count":67,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2018,12,31]],"date-time":"2018-12-31T00:00:00Z","timestamp":1546214400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Ophthalmologica"],"published-print":{"date-parts":[[2019,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>\n                      To review the clinical characteristics and address the aetiology in a group of patients presenting with unilateral retinal pigmentary changes, best described as unilateral pigmentary retinopathy (\n                      <jats:styled-content style=\"fixed-case\">UPR<\/jats:styled-content>\n                      ).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      The cohort of 42 patients was identified retrospectively from the Moorfields Eye Hospital electrophysiology database. All had undergone full\u2010field [electroretinography (\n                      <jats:styled-content style=\"fixed-case\">ERG<\/jats:styled-content>\n                      )] and pattern electroretinography (\n                      <jats:styled-content style=\"fixed-case\">PERG<\/jats:styled-content>\n                      ), with 13 additionally having multifocal ERG (mf\n                      <jats:styled-content style=\"fixed-case\">ERG<\/jats:styled-content>\n                      ). The clinical findings, fundus photographs and fundus autofluorescence (\n                      <jats:styled-content style=\"fixed-case\">AF<\/jats:styled-content>\n                      ) images were reviewed.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      All index eyes showed\n                      <jats:styled-content style=\"fixed-case\">ERG<\/jats:styled-content>\n                      evidence of generalized photoreceptor dysfunction with most showing a similar degree of rod and cone involvement. However, although the fellow eyes all had a normal fundus examination, there were bilateral but asymmetrical\n                      <jats:styled-content style=\"fixed-case\">ERG<\/jats:styled-content>\n                      abnormalities in eight patients and a further four patients had\n                      <jats:styled-content style=\"fixed-case\">PERG<\/jats:styled-content>\n                      evidence of macular dysfunction in the fellow eye. A relevant medical history or the diagnosis of an ophthalmologic entity that might be related to the unilateral fundus changes was ascertained in 15 cases (~36%) including acute zonal occult outer retinopathy, trauma, systemic malignancy or autoimmune disease, retinal vasculitis, presumed pregnancy\u2010related choroidal ischaemia and meningitis. Two patients had a family history of retinitis pigmentosa (\n                      <jats:styled-content style=\"fixed-case\">RP<\/jats:styled-content>\n                      ; 4.8%).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      The underlying aetiology in most cases of UPR cannot accurately be identified, but an heritable cause is unlikely. Aspects of the history clearly suggest an acquired disorder in some patients. Twenty\u2010five patients (60%) with nongenetic\n                      <jats:styled-content style=\"fixed-case\">UPR<\/jats:styled-content>\n                      did not adhere to the pattern of rod greater than cone dysfunction that occurs in RP (rod\u2013cone dystrophy), and the pattern of rod\u00a0&gt;\u00a0cone dysfunction seen in true\n                      <jats:styled-content style=\"fixed-case\">RP<\/jats:styled-content>\n                      is thus not a feature of most patients with\n                      <jats:styled-content style=\"fixed-case\">UPR<\/jats:styled-content>\n                      .\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/aos.13981","type":"journal-article","created":{"date-parts":[[2018,12,31]],"date-time":"2018-12-31T17:40:05Z","timestamp":1546278005000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["Unilateral pigmentary retinopathy: a retrospective case series"],"prefix":"10.1111","volume":"97","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0777-436X","authenticated-orcid":false,"given":"Marie\u2010H\u00e9l\u00e8ne","family":"Errera","sequence":"first","affiliation":[{"name":"Moorfields Eye Hospital London UK"},{"name":"Quinze\u2010Vingts National Ophthalmology Hospital DHU Sight Restore. CIC 1423 Sorbonne\u2010Universit\u00e9s UPMC Universit\u00e9 Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anthony G.","family":"Robson","sequence":"additional","affiliation":[{"name":"Moorfields Eye Hospital London UK"},{"name":"Institute of Ophthalmology University College London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tracey","family":"Wong","sequence":"additional","affiliation":[{"name":"Moorfields Eye Hospital London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philip G.","family":"Hykin","sequence":"additional","affiliation":[{"name":"Moorfields Eye Hospital London UK"},{"name":"Institute of Ophthalmology University College London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bishwanath","family":"Pal","sequence":"additional","affiliation":[{"name":"Moorfields Eye Hospital London UK"},{"name":"Institute of Ophthalmology University College London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mandeep S.","family":"Sagoo","sequence":"additional","affiliation":[{"name":"Moorfields Eye Hospital London UK"},{"name":"Institute of Ophthalmology University College London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos E.","family":"Pavesio","sequence":"additional","affiliation":[{"name":"Moorfields Eye Hospital London UK"},{"name":"Institute of Ophthalmology University College London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anthony T.","family":"Moore","sequence":"additional","affiliation":[{"name":"Moorfields Eye Hospital London UK"},{"name":"Institute of Ophthalmology University College London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew R.","family":"Webster","sequence":"additional","affiliation":[{"name":"Moorfields Eye Hospital London UK"},{"name":"Institute of Ophthalmology University College London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert E.","family":"MacLaren","sequence":"additional","affiliation":[{"name":"Oxford University Hospitals NHS Foundation Trust UK. Nuffield Department of Clinical Neurosciences John Radcliffe Hospital Oxford UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Graham E.","family":"Holder","sequence":"additional","affiliation":[{"name":"Moorfields Eye Hospital London UK"},{"name":"Institute of Ophthalmology University College London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,12,31]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10633-012-9353-y"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9394(14)74652-5"},{"key":"e_1_2_5_4_1","first-page":"1659","article-title":"Retinitis pigmentosa. The Friedenwald lecture","volume":"34","author":"Berson EL","year":"1993","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(99)90064-7"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/IAE.0b013e3181af0d57"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1159\/000308531"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.autrev.2014.01.039"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.1973.01000050023005"},{"key":"e_1_2_5_10_1","first-page":"909","article-title":"Molecular genetics of retinitis pigmentosa in two Romani (Gypsy) families","volume":"12","author":"Chakarova CF","year":"2006","journal-title":"Mol Vis"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00417-006-0313-7"},{"key":"e_1_2_5_12_1","first-page":"325","article-title":"Atypical retinitis pigmentosa: a report of three cases","volume":"24","author":"Contestabile MT","year":"1992","journal-title":"Ann Ophthalmol"},{"key":"e_1_2_5_13_1","first-page":"224","article-title":"Unilateral retinitis pigmentosa","volume":"66","author":"Cordier J","year":"1966","journal-title":"Bull Soc Ophtalmol Fr"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.04-1482"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.2147\/OPTH.S5130"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1038\/eye.2008.59"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.2004.042416"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.1159\/000301252"},{"key":"e_1_2_5_19_1","first-page":"79","article-title":"Acute zonal occult outer retinopathy. Donders Lecture: the Netherlands Ophthalmological Society, Maastricht, Holland, June 19, 1992","volume":"13","author":"Gass JD","year":"1993","journal-title":"J Clin Neuroophthalmol"},{"key":"e_1_2_5_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9394(02)01640-9"},{"key":"e_1_2_5_21_1","doi-asserted-by":"publisher","DOI":"10.1159\/000308911"},{"key":"e_1_2_5_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0420.2004.00362.x"},{"key":"e_1_2_5_23_1","doi-asserted-by":"publisher","DOI":"10.1186\/1750-1172-1-40"},{"key":"e_1_2_5_24_1","first-page":"226","volume-title":"Retinitis pigmentosa","author":"Heckenlively JR","year":"1988"},{"key":"e_1_2_5_25_1","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.118.11.1525"},{"key":"e_1_2_5_26_1","doi-asserted-by":"publisher","DOI":"10.7551\/mitpress\/5557.003.0077"},{"key":"e_1_2_5_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1350-9462(00)00030-6"},{"key":"e_1_2_5_28_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10633-007-9053-1"},{"key":"e_1_2_5_29_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10633-011-9296-8"},{"key":"e_1_2_5_30_1","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.1962.00960020456012"},{"key":"e_1_2_5_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/0014-4835(89)90009-2"},{"key":"e_1_2_5_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(95)30891-3"},{"key":"e_1_2_5_33_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00417-009-1253-9"},{"key":"e_1_2_5_34_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2003-812555"},{"key":"e_1_2_5_35_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.35.2.98"},{"key":"e_1_2_5_36_1","first-page":"489","article-title":"Two cases of unilateral pigmentary degeneration","volume":"72","author":"Kandori F","year":"1968","journal-title":"Nippon Ganka Gakkai Zasshi"},{"key":"e_1_2_5_37_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.48.9.471"},{"key":"e_1_2_5_38_1","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.120.5.567"},{"key":"e_1_2_5_39_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.85.1.110a"},{"key":"e_1_2_5_40_1","doi-asserted-by":"publisher","DOI":"10.1097\/IAE.0b013e31822059ae"},{"key":"e_1_2_5_41_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2008-1050226"},{"key":"e_1_2_5_42_1","first-page":"141","volume-title":"Developmental abnormalities of the eye","author":"Mann I","year":"1957"},{"key":"e_1_2_5_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yexmp.2007.10.006"},{"key":"e_1_2_5_44_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(83)34587-5"},{"key":"e_1_2_5_45_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10633-008-9155-4"},{"key":"e_1_2_5_46_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.survophthal.2010.07.004"},{"key":"e_1_2_5_47_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaophthalmol.2014.1683"},{"key":"e_1_2_5_48_1","doi-asserted-by":"publisher","DOI":"10.1001\/archophthalmol.2011.171"},{"key":"e_1_2_5_49_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2007.11.018"},{"key":"e_1_2_5_50_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.60.5.354"},{"key":"e_1_2_5_51_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1237758"},{"key":"e_1_2_5_52_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00417-005-1186-x"},{"key":"e_1_2_5_53_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.11-7892"},{"key":"e_1_2_5_54_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(78)35596-2"},{"key":"e_1_2_5_55_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.02-1278"},{"key":"e_1_2_5_56_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.2005.071357"},{"key":"e_1_2_5_57_1","doi-asserted-by":"publisher","DOI":"10.1097\/IAE.0b013e318206d155"},{"key":"e_1_2_5_58_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9394(89)90274-2"},{"key":"e_1_2_5_59_1","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2017-222045"},{"key":"e_1_2_5_60_1","doi-asserted-by":"publisher","DOI":"10.1159\/000027324"},{"key":"e_1_2_5_61_1","first-page":"172","article-title":"Chloroquine retinopathy and unilateral sectoral pigmentary degeneration of the retina","volume":"163","author":"Thaler A","year":"1973","journal-title":"Klin Monatsbl Augenheilkd"},{"key":"e_1_2_5_62_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2008-1057427"},{"key":"e_1_2_5_63_1","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.125.2.259"},{"key":"e_1_2_5_64_1","first-page":"401","article-title":"The ocular toxicity of cephaloridine \u2010 A clinical and experimental study","volume":"3","author":"Turut P","year":"1980","journal-title":"J Fr Ophtalmol"},{"key":"e_1_2_5_65_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2012.12.008"},{"key":"e_1_2_5_66_1","first-page":"335","volume-title":"Retina","author":"Weleber R","year":"1994"},{"key":"e_1_2_5_67_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2004.12.104"},{"key":"e_1_2_5_68_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa013452"}],"container-title":["Acta Ophthalmologica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Faos.13981","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/aos.13981","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/aos.13981","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/aos.13981","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,10]],"date-time":"2023-09-10T00:56:43Z","timestamp":1694307403000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/aos.13981"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,12,31]]},"references-count":67,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2019,6]]}},"alternative-id":["10.1111\/aos.13981"],"URL":"https:\/\/doi.org\/10.1111\/aos.13981","archive":["Portico"],"relation":{},"ISSN":["1755-375X","1755-3768"],"issn-type":[{"value":"1755-375X","type":"print"},{"value":"1755-3768","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,12,31]]},"assertion":[{"value":"2018-03-31","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-11-01","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-12-31","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}