{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T13:11:12Z","timestamp":1773321072324,"version":"3.50.1"},"reference-count":21,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2019,2,28]],"date-time":"2019-02-28T00:00:00Z","timestamp":1551312000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001700","name":"Ministry of Education, Culture, Sports, Science and Technology","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001700","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Ophthalmologica"],"published-print":{"date-parts":[[2019,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>To measure retinal oxygen saturation (<jats:styled-content style=\"fixed-case\">SO<\/jats:styled-content><jats:sub>2<\/jats:sub>) in eyes with branch retinal vein occlusion (<jats:styled-content style=\"fixed-case\">BRVO<\/jats:styled-content>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Retinal oximetry was performed using the Oxymap T1 retinal oximeter in 50 eyes (50 patients) with resolved <jats:styled-content style=\"fixed-case\">BRVO<\/jats:styled-content>. <jats:styled-content style=\"fixed-case\">SO<\/jats:styled-content><jats:sub>2<\/jats:sub> was calculated in each major retinal artery and vein in four quadrants. The superior or inferior hemisphere with <jats:styled-content style=\"fixed-case\">BRVO<\/jats:styled-content> was categorized as the affected hemisphere and the other as the unaffected hemisphere.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Oxymap T1 allowed us to measure <jats:styled-content style=\"fixed-case\">SO<\/jats:styled-content><jats:sub>2<\/jats:sub> in major retinal vessels. Both arterial and venous <jats:styled-content style=\"fixed-case\">SO<\/jats:styled-content><jats:sub>2<\/jats:sub> in the affected hemisphere were significantly higher than those in the unaffected hemisphere. However, there was no significant difference in arteriovenous (A\u2010V) difference in <jats:styled-content style=\"fixed-case\">SO<\/jats:styled-content><jats:sub>2<\/jats:sub> between the affected and unaffected hemispheres. Of the 50 included eyes, 32 had non\u2010ischemic <jats:styled-content style=\"fixed-case\">BRVO<\/jats:styled-content> and 18 had ischemic <jats:styled-content style=\"fixed-case\">BRVO<\/jats:styled-content>. In the affected hemisphere, arterial <jats:styled-content style=\"fixed-case\">SO<\/jats:styled-content><jats:sub>2<\/jats:sub> was significantly higher in ischemic <jats:styled-content style=\"fixed-case\">BRVO<\/jats:styled-content> (106.9\u00a0\u00b1\u00a08.8%) than in non\u2010ischemic <jats:styled-content style=\"fixed-case\">BRVO<\/jats:styled-content> (101.3\u00a0\u00b1\u00a09.2%, p\u00a0=\u00a00.044). There were no significant differences in venous <jats:styled-content style=\"fixed-case\">SO<\/jats:styled-content><jats:sub>2<\/jats:sub> between non\u2010ischemic and ischemic <jats:styled-content style=\"fixed-case\">BRVO<\/jats:styled-content>. Consequently, the A\u2010V difference in <jats:styled-content style=\"fixed-case\">SO<\/jats:styled-content><jats:sub>2<\/jats:sub> was significantly higher in ischemic <jats:styled-content style=\"fixed-case\">BRVO<\/jats:styled-content> (51.9\u00a0\u00b1\u00a013.9%) than in non\u2010ischemic <jats:styled-content style=\"fixed-case\">BRVO<\/jats:styled-content> (43.4\u00a0\u00b1\u00a011.5%, p\u00a0=\u00a00.028). In multiple regression analysis, the type of perfusion (non\u2010ischemic or ischemic) had associations with arterial <jats:styled-content style=\"fixed-case\">SO<\/jats:styled-content><jats:sub>2<\/jats:sub> (<jats:italic>\u03b2\u00a0=\u00a00<\/jats:italic>.365, p\u00a0=\u00a00.013) and with A\u2010V differences in <jats:styled-content style=\"fixed-case\">SO<\/jats:styled-content><jats:sub>2<\/jats:sub> in the affected hemisphere (<jats:italic>\u03b2\u00a0=\u00a00<\/jats:italic>.406, p\u00a0=\u00a00.006).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>In ischemic <jats:styled-content style=\"fixed-case\">BRVO<\/jats:styled-content>, arterial <jats:styled-content style=\"fixed-case\">SO<\/jats:styled-content><jats:sub>2<\/jats:sub> and the A\u2010V difference in <jats:styled-content style=\"fixed-case\">SO<\/jats:styled-content><jats:sub>2<\/jats:sub> in the affected hemisphere were significantly higher than in non\u2010ischemic <jats:styled-content style=\"fixed-case\">BRVO<\/jats:styled-content>.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aos.14070","type":"journal-article","created":{"date-parts":[[2019,2,28]],"date-time":"2019-02-28T11:18:23Z","timestamp":1551352703000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Retinal oximetry in branch retinal vein occlusion"],"prefix":"10.1111","volume":"97","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8433-7473","authenticated-orcid":false,"given":"Rie","family":"Osaka","sequence":"first","affiliation":[{"name":"Department of Ophthalmology Kagawa University Faculty of Medicine Miki Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuki","family":"Nakano","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology Kagawa University Faculty of Medicine Miki 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