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Clinical data including intraocular pressure (<jats:styled-content style=\"fixed-case\">IOP<\/jats:styled-content>), visual acuity (<jats:styled-content style=\"fixed-case\">VA<\/jats:styled-content>), number of topical glaucoma medications, use of oral acetazolamide, retreatments and complications during a 2\u2010year follow\u2010up were registered. Global success was defined as <jats:styled-content style=\"fixed-case\">IOP<\/jats:styled-content> 6\u201318\u00a0mmHg with or without glaucoma medication.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Three hundred patients underwent <jats:styled-content style=\"fixed-case\">TCP<\/jats:styled-content> during the time period. Mean <jats:styled-content style=\"fixed-case\">IOP<\/jats:styled-content> at baseline was 29.3\u00a0\u00b1\u00a011.0 (mean\u00a0\u00b1\u00a0standard deviation) mmHg (<jats:italic>n\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>297) with a mean reduction of 11.5 (\u00b112.0) mmHg at 1\u00a0year (<jats:italic>n\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>258; p\u00a0&lt;\u00a00.001) and 12.6 (\u00b112.0) mmHg at 2\u2010year follow\u2010up (<jats:italic>n\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>245; p\u00a0&lt;\u00a00.001). Global success at 2\u00a0years was 64%, achieved by a mean of 1.2 treatments (<jats:italic>n\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>257). The number of topical glaucoma medications at baseline was 3.1 (\u00b11.0; <jats:italic>n\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>296) and was reduced by 0.9 (\u00b11.0) medications at 2\u00a0years (<jats:italic>n\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>244; p\u00a0&lt;\u00a00.001). Use of oral acetazolamide decreased from 30% (<jats:italic>n\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>90) at baseline to 5.3% (<jats:italic>n\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>13) at 2\u00a0years. In eyes with Snellen <jats:styled-content style=\"fixed-case\">VA<\/jats:styled-content>\u00a0\u2265\u00a00.1, the mean <jats:styled-content style=\"fixed-case\">VA<\/jats:styled-content> at baseline was 0.55 (\u00b10.3) logarithm of the minimum angle of resolution (logMAR; <jats:italic>n\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>132) and 1.1 (\u00b10.9) log<jats:styled-content style=\"fixed-case\">MAR<\/jats:styled-content> (<jats:italic>n\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>76) at 2\u00a0years (p\u00a0&lt;\u00a00.001). No cases of phthisis bulbi were found.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This study displays a substantial and long\u2010term reduction of <jats:styled-content style=\"fixed-case\">IOP<\/jats:styled-content> following <jats:styled-content style=\"fixed-case\">TCP<\/jats:styled-content> with a decrease in topical and oral glaucoma medications. The treatment appears to be safe but the decrease in <jats:styled-content style=\"fixed-case\">VA<\/jats:styled-content> during follow\u2010up is a concern that needs further evaluation.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aos.14125","type":"journal-article","created":{"date-parts":[[2019,4,26]],"date-time":"2019-04-26T11:45:39Z","timestamp":1556279139000},"page":"764-770","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Efficacy and safety of transscleral cyclophotocoagulation in Swedish glaucoma patients"],"prefix":"10.1111","volume":"97","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4102-2455","authenticated-orcid":false,"given":"Erika","family":"Rasmuson","sequence":"first","affiliation":[{"name":"Department of Clinical Sciences Ophthalmology Ume\u00e5 University Ume\u00e5 Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christina","family":"Lind\u00e9n","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences Ophthalmology Ume\u00e5 University Ume\u00e5 Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bj\u00f6rn","family":"Lundberg","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences Ophthalmology Ume\u00e5 University Ume\u00e5 Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gauti","family":"J\u00f3hannesson","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences Ophthalmology Ume\u00e5 University Ume\u00e5 Sweden"},{"name":"Wallenberg Center for Molecular Medicine Ume\u00e5 University Ume\u00e5 Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,4,26]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.eye.6702345"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0420.2007.00992.x"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0420.2007.00980.x"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.119.3.345"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1755-3768.2008.01248.x"},{"key":"e_1_2_5_7_1","doi-asserted-by":"crossref","unstructured":"European Glaucoma Society(2017):Terminology and Guidelines for Glaucoma 4th Edition \u2010 Chapter 3: Treatment principles and options. 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