{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T03:06:28Z","timestamp":1790996788193,"version":"4.1.0"},"reference-count":32,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2019,6,18]],"date-time":"2019-06-18T00:00:00Z","timestamp":1560816000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100008723","name":"Suomen L\u00e4\u00e4ketieteen S\u00e4\u00e4ti\u00f6","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008723","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007417","name":"Paulon S\u00e4\u00e4ti\u00f6","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100007417","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Ophthalmologica"],"published-print":{"date-parts":[[2020,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>To compare the efficacy, safety and tolerability of a single perioperative subconjunctival injection of triamcinolone acetonide (TA) with steroid drops for the prevention of macular oedema and ocular inflammation after cataract surgery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This prospective non\u2010randomized controlled clinical trial analysed 101 eyes of 101 patients having an elective cataract surgery at Kymenlaakso Central Hospital, Kotka, Finland. Fifty eyes received conventional postoperative care with dexamethasone 1\u00a0mg\/ml eye drops (DEX), and 51 eyes received a perioperative 20\u00a0mg subconjunctival injection of TA. None of the eyes received postoperative topical antibiotic prophylaxis. The main outcome measures were aqueous flare, central retinal thickness (CRT), corrected distance visual acuity (CDVA) and intraocular pressure (IOP) measured at 7, 28 and 90\u00a0days after surgery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Central retinal thickness (CRT) increased in DEX but not in TA\u2010treated eyes at 7\u00a0days (+1.2\u00a0\u00b1\u00a020.1\u00a0<jats:italic>\u03bc<\/jats:italic>m and \u22129.2\u00a0\u00b1\u00a024.8\u00a0<jats:italic>\u03bc<\/jats:italic>m, p<jats:italic>\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.031), at 28\u00a0days (+23.8\u00a0\u00b1\u00a062.6\u00a0<jats:italic>\u03bc<\/jats:italic>m and \u22123.3\u00a0\u00b1\u00a027.7\u00a0<jats:italic>\u03bc<\/jats:italic>m, p<jats:italic>\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.008) and at 90\u00a0days (+8.5\u00a0\u00b1\u00a024.4\u00a0<jats:italic>\u03bc<\/jats:italic>m and \u22125.5\u00a0\u00b1\u00a033.4\u00a0<jats:italic>\u03bc<\/jats:italic>m, p<jats:italic>\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.026). Aqueous flare increased from baseline in both groups but remained higher in DEX eyes at 90\u00a0days (+3.3\u00a0\u00b1\u00a09.9 photons\/ms and \u22120.2\u00a0\u00b1\u00a06.6 photons\/ms, p<jats:italic>\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.021). Corrected distance visual acuity (CDVA) and IOP changes were similar, and ocular tolerance was good in both groups. No serious adverse events were observed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Perioperative subconjunctival TA was effective in preventing ocular inflammation and macular oedema after cataract surgery. Subconjunctival TA combined with intracameral cefuroxime provides a noteworthy option for dropless postoperative care in modern cataract surgery.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aos.14175","type":"journal-article","created":{"date-parts":[[2019,6,18]],"date-time":"2019-06-18T07:29:56Z","timestamp":1560842996000},"page":"36-42","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":57,"title":["Perioperative subconjunctival triamcinolone acetonide injection for prevention of inflammation and macular oedema after cataract surgery"],"prefix":"10.1111","volume":"98","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4371-9456","authenticated-orcid":false,"given":"Juha\u2010Matti","family":"Lindholm","sequence":"first","affiliation":[{"name":"Helsinki Retina Research Group University of Helsinki Helsinki Finland"},{"name":"Department of Ophthalmology Helsinki University Hospital Helsinki 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