{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T02:35:01Z","timestamp":1780626901703,"version":"3.54.1"},"reference-count":18,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2019,9,8]],"date-time":"2019-09-08T00:00:00Z","timestamp":1567900800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Silm\u00e4s\u00e4\u00e4ti\u00f6, Helsinki, Finland"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Ophthalmologica"],"published-print":{"date-parts":[[2020,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>To study the effect of glaucoma drainage implant (<jats:styled-content style=\"fixed-case\">GDI<\/jats:styled-content>) surgery on corneal topography during the first postoperative year.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Twenty\u2010one adult glaucoma patients were implanted with a Molteno3 or a Baerveldt 250 <jats:styled-content style=\"fixed-case\">GDI<\/jats:styled-content>. Corneal topography measurements were taken preoperatively and at 6 and 12\u00a0months after surgery. Untreated opposite eyes served as controls.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In the surgical group, the mean\u00a0\u00b1\u00a0<jats:styled-content style=\"fixed-case\">SD<\/jats:styled-content> simulated average keratometry values were 44.36\u00a0\u00b1\u00a01.69 D, 44.08\u00a0\u00b1\u00a01.29 D (p\u00a0=\u00a00.266) and 44.15\u00a0\u00b1\u00a01.32 D (p\u00a0=\u00a00.554) before and 6 and 12\u00a0months after surgery, respectively. The corresponding simulated keratometry astigmatism values were 1.11\u00a0\u00b1\u00a01.11 D, 1.20\u00a0\u00b1\u00a01.01 D (p\u00a0=\u00a00.687) and 1.16\u00a0\u00b1\u00a00.71 D (p\u00a0=\u00a00.177). Posterior astigmatism and posterior average keratometry remained unchanged after <jats:styled-content style=\"fixed-case\">GDI<\/jats:styled-content> surgery as well. The mean\u00a0\u00b1\u00a0<jats:styled-content style=\"fixed-case\">SD<\/jats:styled-content> central corneal thickness (<jats:styled-content style=\"fixed-case\">CCT<\/jats:styled-content>) was 530\u00a0\u00b1\u00a046\u00a0<jats:italic>\u03bc<\/jats:italic>m, 535\u00a0\u00b1\u00a056\u00a0<jats:italic>\u03bc<\/jats:italic>m (p\u00a0=\u00a00.049) and 536\u00a0\u00b1\u00a045\u00a0<jats:italic>\u03bc<\/jats:italic>m (p\u00a0=\u00a00.080) at 0, 6 and 12\u00a0months, respectively. A trend towards increased corneal thickness (<jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content>) in response to <jats:styled-content style=\"fixed-case\">GDI<\/jats:styled-content> surgery was also seen in both the average peripheral and the tube\u2010quadrant peripheral <jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content> values. At 12\u00a0months postoperatively, the mean endothelial cell density (<jats:styled-content style=\"fixed-case\">ECD<\/jats:styled-content>) had decreased by 8% centrally and by 9% peripherally. Corneal topography parameters, <jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">ECD<\/jats:styled-content> did not significantly change in the control group during follow\u2010up.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Glaucoma drainage implant (GDI) surgery did not significantly alter corneal keratometry parameters and thus seems to be an astigmatically neutral procedure. However a slight, although seemingly transient, increase in <jats:styled-content style=\"fixed-case\">CCT<\/jats:styled-content> was observed after <jats:styled-content style=\"fixed-case\">GDI<\/jats:styled-content> implantation.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aos.14247","type":"journal-article","created":{"date-parts":[[2019,9,8]],"date-time":"2019-09-08T14:00:23Z","timestamp":1567951223000},"page":"305-309","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Effect of glaucoma drainage implant surgery on corneal topography: a prospective study"],"prefix":"10.1111","volume":"98","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3166-4582","authenticated-orcid":false,"given":"Riku","family":"Koivusalo","sequence":"first","affiliation":[{"name":"Department of Ophthalmology P\u00e4ij\u00e4t\u2010H\u00e4me Central Hospital Lahti 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