{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T15:36:13Z","timestamp":1782228973764,"version":"3.54.5"},"reference-count":13,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2019,11,15]],"date-time":"2019-11-15T00:00:00Z","timestamp":1573776000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001826","name":"ZonMw","doi-asserted-by":"publisher","award":["842005004"],"award-info":[{"award-number":["842005004"]}],"id":[{"id":"10.13039\/501100001826","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010378","name":"Stichting Wetenschappelijk Onderzoek Oogziekenhuis","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100010378","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Ophthalmologica"],"published-print":{"date-parts":[[2020,6]]},"abstract":"Abstract<\/jats:title>Purpose<\/jats:title>Although the Baerveldt glaucoma implant (BGI<\/jats:styled-content>) initially was reserved for refractory glaucoma, its role in the surgical management of glaucoma has shifted towards a primary treatment choice. We performed a randomized prospective study to compare BGI<\/jats:styled-content> surgery and trabeculectomy (TE<\/jats:styled-content>) in patients without previous ocular surgery.<\/jats:p><\/jats:sec>Methods<\/jats:title>We included 119 glaucoma patients without previous ocular surgery. One eye of each subject was randomized to either a BGI<\/jats:styled-content> or TE<\/jats:styled-content>. Follow\u2010up visits were at 1\u00a0day, 2\u00a0weeks, 6\u00a0weeks, 3\u00a0months, 6\u00a0months and 1, 2, 3, 4 and 5\u00a0years postoperatively. Primary outcomes were intraocular pressure (IOP<\/jats:styled-content>) and failure rate. Secondary outcomes were medication, anterior chamber laser flare value and complications.<\/jats:p><\/jats:sec>Results<\/jats:title>After 5\u00a0years, an IOP<\/jats:styled-content> of 12.7\u00a0\u00b1\u00a03.9\u00a0mmHg (mean\u00a0\u00b1\u00a0SD<\/jats:styled-content>) was achieved in the TE<\/jats:styled-content> group and 12.9\u00a0\u00b1\u00a03.9\u00a0mmHg in the BGI<\/jats:styled-content> group. We found no statistically significant difference in failure rate between the groups (p\u00a0=\u00a00.72). More BGI<\/jats:styled-content> patients needed additional medication to control their IOP<\/jats:styled-content> (85%; 1.9\u00a0\u00b1\u00a01.2 types of glaucoma medication) compared to the TE<\/jats:styled-content> patients (57%; 0.5\u00a0\u00b1\u00a00.9 types of glaucoma medication). Diplopia was significantly more present in the BGI<\/jats:styled-content> group than in the TE<\/jats:styled-content> group (27% versus 4%; p\u00a0<\u00a00.001). The self\u2010limiting complication rate was similar in both groups.<\/jats:p><\/jats:sec>Conclusions<\/jats:title>Our study demonstrates that, in the long term, the final IOP<\/jats:styled-content> and failure rate are similar after TE<\/jats:styled-content> and BGI<\/jats:styled-content> surgery. However, the need for additional medication after BGI<\/jats:styled-content> surgery is higher than after TE<\/jats:styled-content>. Also, the increased risk of developing diplopia after BGI<\/jats:styled-content> surgery must be taken into consideration.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aos.14265","type":"journal-article","created":{"date-parts":[[2019,11,15]],"date-time":"2019-11-15T10:35:42Z","timestamp":1573814142000},"page":"400-407","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":25,"title":["Primary baerveldt versus trabeculectomy study after 5\u00a0years of follow\u2010up"],"prefix":"10.1111","volume":"98","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7437-5716","authenticated-orcid":false,"given":"Esma","family":"Islamaj","sequence":"first","affiliation":[{"name":"Rotterdam Eye Hospital Rotterdam Ophthalmic Institute Rotterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0058-3643","authenticated-orcid":false,"given":"Ren\u00e9 J.","family":"Wubbels","sequence":"additional","affiliation":[{"name":"Rotterdam Eye Hospital Rotterdam Ophthalmic Institute Rotterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter W. T.","family":"de Waard","sequence":"additional","affiliation":[{"name":"Glaucoma Department Rotterdam Eye Hospital Rotterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,11,15]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.5041\/RMMJ.10345"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2011.10.026"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2018.02.003"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.119.12.1763"},{"key":"e_1_2_5_6_1","first-page":"344","article-title":"A reconsideration of anterior chamber flare and its clinical relevance for children with chronic anterior uveitis (an American Ophthalmological Society thesis)","volume":"105","author":"Holland G","year":"2007","journal-title":"Trans Am Ophthalmol Soc"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1167\/tvst.7.5.7"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/aos.13658"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1001\/archophthalmol.2011.221"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/aos.13920"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2015.11.017"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1089\/jop.2016.0128"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2011.01.052"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9394(03)00239-3"}],"container-title":["Acta Ophthalmologica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Faos.14265","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/aos.14265","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/aos.14265","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/aos.14265","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,6]],"date-time":"2023-09-06T04:03:17Z","timestamp":1693972997000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/aos.14265"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,11,15]]},"references-count":13,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2020,6]]}},"alternative-id":["10.1111\/aos.14265"],"URL":"https:\/\/doi.org\/10.1111\/aos.14265","archive":["Portico"],"relation":{},"ISSN":["1755-375X","1755-3768"],"issn-type":[{"value":"1755-375X","type":"print"},{"value":"1755-3768","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,11,15]]},"assertion":[{"value":"2019-06-24","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-09-06","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-11-15","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}