{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T06:37:22Z","timestamp":1787726242672,"version":"build-2784847793"},"reference-count":30,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2019,11,26]],"date-time":"2019-11-26T00:00:00Z","timestamp":1574726400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Ophthalmologica"],"published-print":{"date-parts":[[2020,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>To examine ciliary muscle (CM) dimensions <jats:italic>in vivo<\/jats:italic> by swept\u2010source optical coherence tomography (SS\u2010OCT) in a large healthy population. To assess the reproducibility of CM measurements and correlations with different parameters.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In this cross\u2010sectional study, the following CM measurements were made in 495 eyes of 495 subjects in the temporal and nasal quadrants: length (CML), area (CMA) and thickness at distances of 1000\u00a0\u03bcm (CMT1), 2000\u00a0\u03bcm (CMT2) and 3000\u00a0\u03bcm (CMT3) from the scleral spur using the SS\u2010OCT DRI\u2010Triton<jats:sup>\u00ae<\/jats:sup> (Topcon, Tokyo, Japan). These dimensions were then assessed for correlations with the factors age, gender, refractive error, anterior chamber angle (ACA) and intraocular pressure (IOP). The reproducibility of CM measurements was determined in 85 of the participants.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Mean age was 41.4\u00a0\u00b1\u00a017.5\u00a0years (range 5\u201383). The following means were recorded as follows: CML\u00a0=\u00a04.57\u00a0\u00b1\u00a00.73\u00a0mm (range 2.16\u20136.97), CMA\u00a0=\u00a01.35\u00a0\u00b1\u00a00.31\u00a0mm<jats:sup>2<\/jats:sup> (2.04\u20135.45), CMT1\u00a0=\u00a0558\u00a0\u00b1\u00a098\u00a0\u03bcm (299\u2013891), CMT2\u00a0=\u00a0366\u00a0\u00b1\u00a0100\u00a0\u03bcm (89\u2013629) and CMT3\u00a0=\u00a0210\u00a0\u00b1\u00a075\u00a0\u03bcm (36\u2013655). Negative correlation was detected between CML\/CMA and age (<jats:italic>R<\/jats:italic>\u00a0=\u00a0\u22120.516\/<jats:italic>R<\/jats:italic>\u00a0=\u00a0\u22120.404; p\u00a0&lt;\u00a00.001) and refractive error (<jats:italic>R<\/jats:italic>\u00a0=\u00a0\u22120.519\/<jats:italic>R<\/jats:italic>\u00a0=\u00a0\u22120.538; p\u00a0&lt;\u00a00.001). No gender differences were observed (p\u00a0\u2265\u00a00.150). Both CML and CMA were correlated with ACA (<jats:italic>R<\/jats:italic>\u00a0=\u00a00.498 and 0.546; p\u00a0&lt;\u00a00.001) and slightly with IOP (<jats:italic>R<\/jats:italic>\u00a0=\u00a0\u22120.175; p\u00a0&lt;\u00a00.001). The reproducibility of the CM measurements was excellent (intraclass correlation coefficient \u22650.878).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Swept\u2010source optical coherence tomography is a valid tool for <jats:italic>in vivo<\/jats:italic> CM measurements. Our data indicate a larger CM in myopes and its diminishing size with age.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aos.14304","type":"journal-article","created":{"date-parts":[[2019,11,27]],"date-time":"2019-11-27T05:22:50Z","timestamp":1574832170000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Ciliary muscle dimensions by swept\u2010source optical coherence tomography and correlation study in a large population"],"prefix":"10.1111","volume":"98","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8745-3464","authenticated-orcid":false,"given":"Jos\u00e9 Ignacio","family":"Fern\u00e1ndez\u2010Vigo","sequence":"first","affiliation":[{"name":"Department of Ophthalmology Hospital Cl\u00ednico San Carlos Instituto de Investigaci\u00f3n Sanitaria (IdISSC) Madrid Spain"},{"name":"Centro Internacional de Oftalmolog\u00eda Avanzada Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hang","family":"Shi","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology Hospital Cl\u00ednico San Carlos Instituto de Investigaci\u00f3n Sanitaria (IdISSC) Madrid Spain"},{"name":"Centro Internacional de Oftalmolog\u00eda Avanzada Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bachar","family":"Kudsieh","sequence":"additional","affiliation":[{"name":"Centro Internacional de Oftalmolog\u00eda Avanzada Madrid Spain"},{"name":"Department of Ophthalmology Hospital Puerta de Hierro Majadahonda Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pedro","family":"Arriola\u2010Villalobos","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology Hospital Cl\u00ednico San Carlos Instituto de Investigaci\u00f3n Sanitaria (IdISSC) Madrid Spain"},{"name":"Centro Internacional de Oftalmolog\u00eda Avanzada Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luc\u00eda","family":"De\u2010Pablo G\u00f3mez\u2010de\u2010Lia\u00f1o","sequence":"additional","affiliation":[{"name":"Centro Internacional de Oftalmolog\u00eda Avanzada Madrid Spain"},{"name":"Department of Ophthalmology Hospital 12 de Octubre Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juli\u00e1n","family":"Garc\u00eda\u2010Feij\u00f3o","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology Hospital Cl\u00ednico San Carlos Instituto de Investigaci\u00f3n Sanitaria (IdISSC) Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 \u00c1ngel","family":"Fern\u00e1ndez\u2010Vigo","sequence":"additional","affiliation":[{"name":"Centro Internacional de Oftalmolog\u00eda Avanzada Madrid Spain"},{"name":"Department of Ophthalmology Universidad de Extremadura Badajoz Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,11,26]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.1992.01080180074031"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.preteyeres.2018.04.002"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.11-7313"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.08-2008"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.exer.2016.07.007"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.optom.2018.01.001"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00417-017-3663-4"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(99)00502-3"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006324-200106000-00014"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9394(99)00353-0"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/OPX.0b013e3182044b94"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/IJG.0b013e318285fede"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/OPX.0000000000000070"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clae.2015.05.007"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00417-018-4085-7"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1038\/eye.2008.178"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00417-017-3809-4"},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2005.01.047"},{"key":"e_1_2_5_20_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006324-200004000-00013"},{"key":"e_1_2_5_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/ceo.12057"},{"key":"e_1_2_5_22_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.13-11658"},{"key":"e_1_2_5_23_1","doi-asserted-by":"publisher","DOI":"10.1364\/BOE.7.001351"},{"key":"e_1_2_5_24_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.10-5787"},{"key":"e_1_2_5_25_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.10-6447"},{"key":"e_1_2_5_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.preteyeres.2004.11.001"},{"key":"e_1_2_5_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2018.07.017"},{"key":"e_1_2_5_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/0047-6374(92)90057-K"},{"key":"e_1_2_5_29_1","doi-asserted-by":"publisher","DOI":"10.1364\/BOE.9.005100"},{"key":"e_1_2_5_30_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.16-19558"},{"key":"e_1_2_5_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2013.10.035"}],"container-title":["Acta Ophthalmologica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/aos.14304","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/aos.14304","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/aos.14304","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,6]],"date-time":"2023-09-06T04:03:46Z","timestamp":1693973026000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/aos.14304"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,11,26]]},"references-count":30,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2020,6]]}},"alternative-id":["10.1111\/aos.14304"],"URL":"https:\/\/doi.org\/10.1111\/aos.14304","archive":["Portico"],"relation":{},"ISSN":["1755-375X","1755-3768"],"issn-type":[{"value":"1755-375X","type":"print"},{"value":"1755-3768","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,11,26]]},"assertion":[{"value":"2019-06-04","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-10-31","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-11-26","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}