{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T04:33:01Z","timestamp":1789187581371,"version":"build-2803163510"},"reference-count":44,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2019,11,26]],"date-time":"2019-11-26T00:00:00Z","timestamp":1574726400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Ophthalmologica"],"published-print":{"date-parts":[[2020,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>This study examines aniseikonia, Aniseikonia tolerance range (<jats:styled-content style=\"fixed-case\">ATR<\/jats:styled-content>), anisometropia and patient\u2010reported outcomes (<jats:styled-content style=\"fixed-case\">PRO<\/jats:styled-content>) in an anisometropic population compared with a non\u2010anisometropic population. The relationship between anisometropia and aniseikonia is determined, and the correlations between aniseikonia, anisometropia and <jats:styled-content style=\"fixed-case\">ATR<\/jats:styled-content> versus <jats:styled-content style=\"fixed-case\">PRO<\/jats:styled-content> are described.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>One hundred and twenty\u2010three patients with <jats:styled-content style=\"fixed-case\">IOL<\/jats:styled-content>\u2010induced anisometropia \u22651 dioptre (D) (the anisometropic group) and 17 patients who had <jats:styled-content style=\"fixed-case\">IOL<\/jats:styled-content>\u2010induced anisometropia &lt;1 D (the control group) were included. Best corrected visual acuity, aniseikonia, <jats:styled-content style=\"fixed-case\">ATR<\/jats:styled-content> and stereoacuity were examined, and two questionnaires were completed: convergence insufficiency symptom survey (<jats:styled-content style=\"fixed-case\">CISS<\/jats:styled-content>) and Visual Function Questionnaire (<jats:styled-content style=\"fixed-case\">VFQ<\/jats:styled-content>\u201039).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>One hundred and thirteen patients had anisometropia &gt;1 and &lt;3 D, and 10 patients had anisometropia &gt;3 D. There was no difference in <jats:styled-content style=\"fixed-case\">PRO<\/jats:styled-content> between the control group and the anisometropic group (Mann\u2013Whitney, p\u2010values <jats:styled-content style=\"fixed-case\">VFQ<\/jats:styled-content>: 0.96, <jats:styled-content style=\"fixed-case\">CISS<\/jats:styled-content>: 0.06). There was no correlation between anisometropia and <jats:styled-content style=\"fixed-case\">PRO<\/jats:styled-content> (Spearman's rank correlation test p\u2010values: <jats:styled-content style=\"fixed-case\">VFQ<\/jats:styled-content>: 0.54, <jats:styled-content style=\"fixed-case\">CISS<\/jats:styled-content>: 0.57). Patients with low <jats:styled-content style=\"fixed-case\">ATR<\/jats:styled-content> were more sensitive towards anisometropia and had lower <jats:styled-content style=\"fixed-case\">PRO<\/jats:styled-content> than patients with high <jats:styled-content style=\"fixed-case\">ATR<\/jats:styled-content> (Mann\u2013Whitney, p\u2010values: <jats:styled-content style=\"fixed-case\">VFQ<\/jats:styled-content>: 0.0008, <jats:styled-content style=\"fixed-case\">CISS<\/jats:styled-content>: 0.11). A large tolerance of aniseikonia was observed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>No correlation between <jats:styled-content style=\"fixed-case\">PRO<\/jats:styled-content> and anisometropia or aniseikonia was found. Patients with low <jats:styled-content style=\"fixed-case\">ATR<\/jats:styled-content> are at risk of visual complaints if they are exposed to <jats:styled-content style=\"fixed-case\">IOL<\/jats:styled-content>\u2010induced anisometropia. <jats:styled-content style=\"fixed-case\">ATR<\/jats:styled-content> might be a future screening tool in cataract patients.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aos.14310","type":"journal-article","created":{"date-parts":[[2019,11,27]],"date-time":"2019-11-27T05:20:06Z","timestamp":1574832006000},"page":"418-426","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":38,"title":["The tolerance of anisometropia"],"prefix":"10.1111","volume":"98","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8543-2843","authenticated-orcid":false,"given":"Therese Gr\u00f8nh\u00f8j","family":"Krarup","sequence":"first","affiliation":[{"name":"Department of Ophthalmology Rigshospitalet\u2010Glostrup Glostrup Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1680-4949","authenticated-orcid":false,"given":"Ivan","family":"Nisted","sequence":"additional","affiliation":[{"name":"Faculty of Health Institute for Clinical Medicine Aarhus N Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ulrik","family":"Christensen","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology Rigshospitalet\u2010Glostrup Glostrup Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1054-1460","authenticated-orcid":false,"given":"Jens Folke","family":"Kiilgaard","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology Rigshospitalet\u2010Glostrup Glostrup Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Morten","family":"la Cour","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology Rigshospitalet\u2010Glostrup Glostrup Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,11,26]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1444-0938.1944.tb00177.x"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1167\/10.2.23"},{"key":"e_1_2_6_4_1","first-page":"213","article-title":"[Aniseikonia. 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