{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,22]],"date-time":"2026-03-22T03:33:15Z","timestamp":1774150395151,"version":"3.50.1"},"reference-count":32,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2020,3,12]],"date-time":"2020-03-12T00:00:00Z","timestamp":1583971200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Ophthalmologica"],"published-print":{"date-parts":[[2020,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>To report the prevalence of pseudoexfoliation (PEX) syndrome and glaucoma associated with PEX (PEX\u2010G) and their relating factors of them in a south\u2010western island of Japan.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A population\u2010based survey of all residents aged\u00a0\u2265\u00a040\u00a0years was conducted in Kumejima, Okinawa, Japan, and 3762 subjects (participation rate, 81.2%) underwent detailed ophthalmic examinations. Presence of PEX material on the lens capsule, iris surface and\/or pupillary margin was determined by slit\u2010lamp biomicroscopy. Glaucoma was diagnosed according to the criteria of the International Society of Geographical and Epidemiological Ophthalmology.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In subjects aged\u00a0\u2265\u00a040\u00a0years, prevalence rates of PEX syndrome, PEX without glaucoma and PEX\u2010G in at least one eye were 1.5% (95% confidence interval [CI]: 1.0\u20131.9%), 1.3% (95% CI: 0.9\u20131.7%) and 0.1% (95% CI: 0.0\u20130.2%), respectively, excluding eyes after cataract surgery; and 2.8% (95% CI: 2.3\u20133.3%), 2.2% (95% CI: 1.8\u20132.6 %) and 0.4% (95% CI: 0.2\u20130.6%), respectively, including eyes after cataract surgery. Cataract surgery had been performed in 61% of subjects with PEX in at least one eye; presence of PEX showed no significant effects on the intraocular pressure (IOP). A multivariate analysis showed that PEX was associated with older age (p\u00a0&lt;\u00a00.0001, odds ratio: 1.10 [95% CI: 1.07\u20131.13]) and working outdoors (p\u00a0=\u00a00.0395, odds ratio: 2.18 [95% CI: 0.99\u20134.82]).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The prevalence rates of PEX syndrome and PEX\u2010G in a south\u2010western island of Japan were reported. PEX showed no significant effect on IOP, and age and working outdoors were significantly related with PEX.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aos.14396","type":"journal-article","created":{"date-parts":[[2020,3,12]],"date-time":"2020-03-12T07:24:30Z","timestamp":1583997870000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Pseudoexfoliation syndrome and relating factors in a rural Japanese population: the Kumejima Study"],"prefix":"10.1111","volume":"98","author":[{"given":"Yoshikuni","family":"Arakaki","sequence":"first","affiliation":[{"name":"Department of Ophthalmology Graduate School of Medicine University of the Ryukyus Okinawa Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shoichi","family":"Sawaguchi","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology Graduate School of Medicine University of the Ryukyus Okinawa Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aiko","family":"Iwase","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology Tajimi Iwase Eye Clinic Gifu Tajimi Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3278-9662","authenticated-orcid":false,"given":"Atsuo","family":"Tomidokoro","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology Higashi\u2010Nakano Eye Clinic Tokyo Japan"},{"name":"Department of Ophthalmology University of Tokyo Graduate School of Medicine Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Makoto","family":"Araie","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology University of Tokyo Graduate School of Medicine Tokyo Japan"},{"name":"Kanto General Hospital of The Mutual Aid Association of Public School Teachers Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,3,12]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.2008.141523"},{"key":"e_1_2_4_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.exer.2016.11.011"},{"key":"e_1_2_4_4_1","volume-title":"Automated static perimetry","author":"Anderson DR","year":"1999"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0420.2007.01051.x"},{"key":"e_1_2_4_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1755-3768.1974.tb01753.x"},{"key":"e_1_2_4_7_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.86.2.238"},{"key":"e_1_2_4_8_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.2003.020016"},{"key":"e_1_2_4_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10038-005-0322-0"},{"key":"e_1_2_4_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(04)00665-7"},{"key":"e_1_2_4_11_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0076770"},{"key":"e_1_2_4_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0420.1997.tb00640.x"},{"key":"e_1_2_4_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1755-3768.1978.tb05685.x"},{"key":"e_1_2_4_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9394(02)02271-7"},{"key":"e_1_2_4_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1442-9071.2011.02696.x"},{"key":"e_1_2_4_16_1","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.117.10.1319"},{"key":"e_1_2_4_17_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.ijg.0000185436.15675.b3"},{"key":"e_1_2_4_18_1","first-page":"951","article-title":"Pseudoexfoliation syndrome for the comprehensive ophthalmologist","volume":"105","author":"Naumann GO","year":"1998","journal-title":"Intraocular and systemic manifestations. 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