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At 5\u00a0years, IGF\u2010binding protein 3 and blood pressure were also measured. A detailed ophthalmological examination including ocular dimensions, fundus morphology, visual fields, visual evoked potentials and perceptual visual dysfunction was performed. Children born to preeclamptic mothers (<jats:italic>n<\/jats:italic>\u00a0=\u00a024) were compared to children with non\u2010preeclamptic mothers (<jats:italic>n<\/jats:italic>\u00a0=\u00a054).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Children exposed to preeclampsia had lower weight (p\u00a0=\u00a00.0002, mean difference \u22121.46, 95% CI \u22122.09; \u22120.83), length (p\u00a0=\u00a00.013, \u22121.10, 95% CI \u22121.92; \u22120.23) and IGF\u2010I levels (p\u00a0=\u00a00.0002, \u221226.0, 95% CI \u221236.0; \u221216.1) at birth compared to non\u2010exposed children. At 5\u00a0years of age, the preeclamptic group had larger optic cup areas (p\u00a0=\u00a00.0006, 0.32, 95% CI 0.15; 0.46, in right eye, p\u00a0=\u00a00.049, 0.18, 95% CI 0.001; 0.35, in left eye). There was no significant difference between the groups regarding other ophthalmological findings or blood pressure. Children with reduced eye motility had lower neonatal IGF\u2010I levels (p\u00a0=\u00a00.033, 15.5, 95% CI 1.1; 30.3).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Preeclampsia was shown to affect growth and IGF\u2010I levels, confirming previous studies. Children exposed to preeclampsia were shown to have larger optic cup areas. Furthermore, lower neonatal IGF\u2010I levels were seen in preterm children with reduced eye motility at 5\u00a0years of age.<\/jats:p><\/jats:sec>","DOI":"10.1111\/aos.14455","type":"journal-article","created":{"date-parts":[[2020,4,30]],"date-time":"2020-04-30T19:09:13Z","timestamp":1588273753000},"page":"671-678","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Ocular findings and growth in 5\u2010year\u2010old preterm children born to mothers with preeclampsia"],"prefix":"10.1111","volume":"98","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7784-0521","authenticated-orcid":false,"given":"Alexandra","family":"Lind","sequence":"first","affiliation":[{"name":"Department of Clinical Neuroscience Institute of Neuroscience and Physiology Sahlgrenska Academy University of Gothenburg Gothenburg 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